| NCT06435221 | Safety Study of Cytisinicline in Adult Combustible and/or E-cigarette Smokers | ACTIVE_NOT_RECRUITING | PHASE3 | 2024-05-28 | 2025-12-31 | 2025-12-31 |
| NCT05981768 | Study to Evaluate Effect of Food on Bioavailability of Single 3 mg Tablet and Pharmacokinetics (PK) of Multiple 3 mg Doses in Healthy Adult Smokers | COMPLETED | PHASE1 | 2023-08-08 | 2023-09-21 | 2023-09-21 |
| NCT05631938 | Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics of a Single 3 mg Cytisinicline Dose | COMPLETED | PHASE1 | 2023-01-10 | 2023-09-04 | 2023-09-04 |
| NCT05566288 | Study to Evaluate Electrocardiographic Effects of Therapeutic & Supratherapeutic Doses of Cytisinicline in Healthy Smokers | COMPLETED | PHASE1 | 2022-10-17 | 2022-12-23 | 2022-12-23 |
| NCT05431387 | A Study of Cytisinicline for Vaping Cessation in Adult Smokers | COMPLETED | PHASE2 | 2022-07-13 | 2023-02-28 | 2023-02-28 |
| NCT05206370 | A Second Study of Cytisinicline for Smoking Cessation in Adult Smokers | COMPLETED | PHASE3 | 2022-01-20 | 2023-03-21 | 2023-03-21 |
| NCT04576949 | A Study of Cytisinicline for Smoking Cessation in Adult Smokers | COMPLETED | PHASE3 | 2020-10-13 | 2021-12-23 | 2021-12-23 |
| NCT03848208 | A Single Dose-escalation Study of Cytisine in Adult Smokers | COMPLETED | PHASE1 | 2019-02-28 | 2019-09-12 | 2019-09-12 |
| NCT03709823 | Trial of Cytisine in Adult Smokers | COMPLETED | PHASE2 | 2018-11-13 | 2019-04-23 | 2019-04-23 |
| NCT03509948 | A Study in Healthy Smokers to Investigate the Effect of Food on the Bioavailability of Cytisine in a New Formulation | COMPLETED | PHASE1 | 2018-04-27 | 2018-06-12 | 2018-06-10 |
| NCT03303911 | A Pharmacokinetic and Pharmacodynamic Evaluation of Cytisine in Healthy Smokers | TERMINATED | PHASE1, PHASE2 | 2017-10-06 | 2018-10-05 | 2018-10-05 |
| NCT03268343 | A Study in Healthy Volunteers to Investigate the Effect of Food on the Bioavailability of Cytisine | COMPLETED | PHASE1 | 2017-08-08 | 2017-09-01 | 2017-08-26 |
| NCT01874561 | Thorough QT/QTc (Corrected QT Interval) Study to Evaluate the Effect of Custirsen on Cardiac Repolarization | COMPLETED | PHASE1 | 2013-05 | 2014-01 | 2013-12 |
| NCT01630733 | A Multinational, Randomized, Open-Label Study of Custirsen In Patients With Advanced or Metastatic (Stage IV) Non-Small Cell Lung Cancer | UNKNOWN | PHASE3 | 2012-09 | 2017-07 | 2017-07 |
| NCT01578655 | Comparison of Cabazitaxel/Prednisone Alone or in Combination With Custirsen for 2nd Line Chemotherapy in Prostate Cancer | COMPLETED | PHASE3 | 2012-08 | 2016-07 | 2016-07 |
| NCT01497470 | A Clinical Study in Cancer Patients to Investigate the Potential Impact of Custirsen, on the Blood Levels of the Chemotherapeutic Drug, Paclitaxel, When Given Together as Part of a Treatment Regimen | COMPLETED | PHASE1 | 2012-04 | 2013-10 | 2013-07 |
| NCT01454089 | A Phase 2 Study Comparing Chemotherapy in Combination With OGX-427 or Placebo in Patients With Bladder Cancer | COMPLETED | PHASE2 | 2011-10 | 2014-11 | 2014-11 |
| NCT01188187 | Comparison of Docetaxel/Prednisone to Docetaxel/Prednisone in Combination With OGX-011 in Men With Prostate Cancer | COMPLETED | PHASE3 | 2010-11 | 2014-06 | 2014-02 |
| NCT01083615 | A Study Evaluating the Pain Palliation Benefit of Adding Custirsen to Docetaxel Retreatment or Cabazitaxel as Second Line Therapy in Men With Metastatic Castrate Resistant Prostate Cancer (mCRPC) | TERMINATED | PHASE3 | 2010-03 | 2013-03 | 2013-03 |
| NCT00487786 | Safety Study of an Antisense Product in Prostate, Ovarian, NSCL, Breast or Bladder Cancer | COMPLETED | PHASE1 | 2007-06 | 2011-10 | 2011-06 |
| NCT00385177 | Phase 1 Dose Escalation Study of SN2310 Injectable Emulsion in Patients With Advanced Solid Tumors | COMPLETED | PHASE1 | 2006-09 | 2009-05 | 2008-12 |
| NCT00327340 | Evaluation of Safety and Feasibility of OGX-011 in Combination With 2nd-line Chemotherapy in Patients With HRPC | COMPLETED | PHASE2 | 2006-07 | 2010-10 | 2010-10 |
| NCT00251095 | Comparison of Safety and Efficacy of TOCOSOL(R) Paclitaxel Versus Taxol(R) for Treatment of Metastatic Breast Cancer | TERMINATED | PHASE3 | 2005-09 | 2007-09 | 2007-09 |
| NCT00138658 | A Study of OGX-011/Gemcitabine/Platinum-Based Regimen in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) | COMPLETED | PHASE1, PHASE2 | 2004-11 | 2010-03 | 2010-03 |
| NCT00096668 | Evaluation of Safety and Efficacy of TOCOSOL(R) Paclitaxel as Initial Treatment for Metastatic Breast Cancer | COMPLETED | PHASE2 | 2004-10 | 2007-09 | 2007-09 |
| NCT00077688 | TOCOSOL(TM) Paclitaxel in Metastatic or Locally Advanced Unresectable Transitional Cell Carcinoma of the Urothelium | COMPLETED | PHASE2 | 2003-11 | 2007-09 | |
| NCT00034164 | Safety and Efficacy of S-8184 in Second Line Treatment of Relapsed Stage IIIB or IV Non Small Cell Lung Cancer | COMPLETED | PHASE2 | 2002-04 | 2007-09 | 2007-09 |
| NCT00034177 | Safety and Efficacy of S-8184 in Treatment of Locally Advanced, Metastatic, or Recurrent TCC of the Urothelium | COMPLETED | PHASE2 | 2002-04 | 2007-09 | 2007-09 |
| NCT00034190 | Safety and Efficacy of S-8184 in Second Line Treatment of Stage III or IV Colorectal Adenocarcinoma | COMPLETED | PHASE2 | 2002-03 | 2007-09 | 2007-09 |
| NCT00034151 | Safety and Efficacy of S-8184 in Second Line Treatment of Stage III or IV Ovarian Cancer | COMPLETED | PHASE2 | 2002-03 | 2007-09 | 2007-09 |