Clinical Trials - GLPG

NCT IDTitleStatusPhasesStart DateCompletion DatePrimary Completion Date
NCT06652633Long-term Follow-up of Participants Treated With Galapagos Chimeric Antigen Receptor (CAR) T-cell TherapiesRECRUITINGPHASE32024-09-092039-072039-07
NCT06043739Relative Bioavailability and Effect of Food Study With an Oral Mini-tablet Formulation of Filgotinib in Healthy SubjectsCOMPLETEDPHASE12023-09-222023-11-122023-10-27
NCT05856448A Study Evaluating the Effects of GLPG3667 Administered As Oral Treatment in Adult Participants with Active Systemic Lupus ErythematosusACTIVE_NOT_RECRUITINGPHASE22023-06-282026-032025-10
NCT05695950A Study Evaluating the Effects of GLPG3667 Given as Oral Treatment for up to 24 Weeks in Adults With DermatomyositisACTIVE_NOT_RECRUITINGPHASE22023-02-272026-042025-10
NCT05479058A Study Evaluating the Effect of Filgotinib Dose De-escalation in Participants With Ulcerative Colitis (UC) in RemissionTERMINATEDPHASE32022-07-262023-10-092023-10-09
NCT05335447Evaluation of Mass Balance and Absolute Bioavailability of GLPG3667COMPLETEDPHASE12022-04-192022-06-032022-06-03
NCT06561425A Study Evaluating the Safety and Efficacy of GLPG5101 (19CP02) in Participants With Non-Hodgkin LymphomaRECRUITINGPHASE1, PHASE22022-03-092029-07-012029-07-01
NCT05272683Drug-drug Interaction Study with GLPG3667 and Itraconazole in Healthy SubjectsCOMPLETEDPHASE12022-02-282022-04-222022-04-01
NCT05030857Drug-drug Interaction and Food-effect Study With GLPG4716 and Midazolam in Healthy SubjectsCOMPLETEDPHASE12021-09-082021-11-132021-11-13
NCT04976270A Study to Evaluate How Well Single and Multiple Doses of GLPG3667 Are Tolerated in Healthy, Adult SubjectsCOMPLETEDPHASE12021-07-202022-01-142022-01-14
NCT04971746Drug-drug Interaction Study with GLPG4716 and Nintedanib and Pirfenidone in Healthy SubjectsCOMPLETEDPHASE12021-07-192022-05-092022-05-09
NCT04907149Evaluation of Mass Balance and Absolute Bioavailability of GLPG3970COMPLETEDPHASE12021-06-072021-07-122021-07-12
NCT04856358A Study to Evaluate How Well Single and Multiple Doses of GLPG3121-modified Release Formulation Are Tolerated in Healthy, Adult SubjectsCOMPLETEDPHASE12021-04-272021-11-082021-11-08
NCT04700280A Study Evaluating the Effects of GLPG3970 Given as an Oral Treatment for 12 Weeks in Adults With Active Primary Sjögren's Syndrome (pSS)TERMINATEDPHASE22021-01-282021-12-272021-10-28
NCT04736927Drug-drug Interaction Study With GLPG3667 and Midazolam in Healthy SubjectsCOMPLETEDPHASE12021-01-152021-02-252021-02-25
NCT04704739Evaluation of Mass Balance and Absolute Bioavailability of GLPG1205COMPLETEDPHASE12021-01-132021-03-102021-03-02
NCT04720183Drug-drug Interaction Study with GLPG3970 and Sulfasalazine in Adult, Healthy SubjectsCOMPLETEDPHASE12021-01-112021-04-232021-04-21
NCT04708184A Study to Assess Relative Bioavailability of and Effect of Food on a New Oral Tablet Formulation of GLPG3970COMPLETEDPHASE12021-01-112021-02-252021-02-25
NCT04700267A Study Evaluating the Effects of GLPG3970 Given as Oral Treatment for 12 Weeks in Adults With Systemic Lupus ErythematosusTERMINATEDPHASE12020-12-282021-10-062021-10-06
NCT04578548A Study to Evaluate the Effects of GLPG2737 in Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)TERMINATEDPHASE22020-11-102023-04-042022-12-14
NCT04653467A Study to Evaluate How Well Single and Multiple Doses of GLPG4399 Are Tolerated in Healthy, Adult SubjectsCOMPLETEDPHASE12020-11-062022-01-102022-01-10
NCT04594928A Study Evaluating the Effects of GLPG3667 Given as an Oral Treatment for 4 Weeks in Adults With Moderate to Severe Plaque PsoriasisCOMPLETEDPHASE12020-10-192021-05-042021-05-04
NCT04577781A Study Evaluating the Effects of GLPG3970 Given as an Oral Treatment for 6 Weeks in Adults With Moderately to Severely Active Rheumatoid Arthritis and an Inadequate Response to MethotrexateCOMPLETEDPHASE22020-10-122021-04-072021-03-26
NCT04577794A Study Evaluating the Effects of GLPG3970 Given as an Oral Treatment for 6 Weeks in Adults With Ulcerative ColitisCOMPLETEDPHASE22020-10-052021-05-312021-05-17
NCT04575818A Study in Healthy Male Volunteers Investigating the Safety, Absorption and Elimination of Single Doses of GLPG4059TERMINATEDPHASE12020-09-162021-04-082021-04-08
NCT04532567A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GLPG1205 in Healthy Japanese and Caucasian Male SubjectsCOMPLETEDPHASE12020-08-182020-12-102020-12-10
NCT04137341A Study in Healthy Volunteers to Compare Different Tablet Formulations of the Test Medicine, GLPG1972, Against the Current Tablet Formulation, and to Assess the Effect Food Has on One of the Test MedicinesCOMPLETEDPHASE12019-10-092019-12-132019-12-13
NCT04097938A Study to Evaluate the Effects of Single and Multiple Oral Doses of GLPG3667COMPLETEDPHASE12019-09-182020-07-062020-03-04
NCT04136327A Study in Healthy Male Volunteers to Test How the Test Medicine GLPG1972 is Taken up by the Body When Given by Mouth and Into the Vein as an InjectionCOMPLETEDPHASE12019-09-132019-10-212019-10-21
NCT04106297A Study to Evaluate the Effects of Single and Multiple Oral Doses of GLPG3970COMPLETEDPHASE12019-09-102021-03-052021-03-05
NCT03976648A Clinical Study to Test Long Term Safety of GLPG1690 for Patients With Systemic SclerosisTERMINATEDPHASE22019-07-182021-04-132021-04-13
NCT03926195Study to Evaluate the Effect of Filgotinib on Semen Parameters in Adult Males With Active Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, or Non-radiographic Axial SpondyloarthritisCOMPLETEDPHASE22019-05-282023-05-102020-08-14
NCT03899909A Study to Evaluate the Effects of a Single and Multiple Oral Doses of GLPG3121 in Adult, Healthy, Male SubjectsCOMPLETEDPHASE12019-03-292019-06-032019-06-03
NCT03864627A Study to Evaluate the Safety and Tolerability of MOR106 Administered Concomitantly With Topical Corticosteroids, in Adult Participants With Moderate to Severe Atopic DermatitisTERMINATEDPHASE22019-03-252020-02-272020-02-27
NCT03800472A Study Investigating the Safety, Absorption and Elimination of GLPG3312, a New Drug in the Treatment of Inflammatory DiseasesCOMPLETEDPHASE12019-01-152020-03-102020-03-10
NCT03798366A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Systemic SclerosisCOMPLETEDPHASE22019-01-142020-06-222020-05-21
NCT03711162A Clinical Study to Test How Effective and Safe GLPG1690 is for Subjects With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of CareTERMINATEDPHASE32018-11-282021-03-302021-03-30
NCT03787186A Study in Healthy Male Volunteers to Look at How the Test Medicine GLPG1690 is Taken up by the Body When Given by Mouth and Into a Vein as an InjectionCOMPLETEDPHASE12018-11-092019-01-172019-01-17
NCT03733444A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of CareTERMINATEDPHASE32018-11-052021-03-302021-03-30
NCT03725852A Clinical Study to Test How Effective and Safe GLPG1205 is for Participants With Idiopathic Pulmonary Fibrosis (IPF)COMPLETEDPHASE22018-09-272020-08-142020-07-21
NCT03595618A Study to Assess Efficacy and Safety of GLPG1972/S201086 in Participants With Knee OsteoarthritisCOMPLETEDPHASE22018-08-142020-07-142020-07-14
NCT03689829A Study to Test Safety, Tolerability, and the Way the Body Absorbs, Distributes, and Gets Rid of a Study Drug Called MOR106, in Healthy Subjects and in Patients With Moderate to Severe Atopic DermatitisTERMINATEDPHASE12018-08-132020-03-022020-03-02
NCT03540524A Study Looking at the Safety, Tolerability and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737 in Patients With Cystic Fibrosis.COMPLETEDPHASE12018-05-312019-03-112019-03-11
NCT03568071A Study to Assess Efficacy, Safety, Tolerability and Pharmacokinetics (PK)/Pharmacodynamics (PD) of MOR106 in Subjects With Moderate to Severe Atopic DermatitisTERMINATEDPHASE22018-04-262020-03-032020-03-03
NCT03515382A Study in Healthy Male Volunteers to Look at How the Test Medicine GLPG1690 is Taken up by the Body When Doses of Itraconazole and Voriconazole Are Given to Healthy VolunteersCOMPLETEDPHASE12018-03-162018-06-012018-06-01
NCT03589313Pharmacokinetics of GLPG3067 in Male Subjects With Cystic Fibrosis.COMPLETEDPHASE12018-02-122018-03-262018-03-26
NCT03474042GLPG2737 on Top of Orkambi in Subjects With Cystic FibrosisCOMPLETEDPHASE22017-11-292018-04-102018-04-10
NCT03320876An Open-label, Long-term Extension Study With Filgotinib in Active Psoriatic Arthritis.TERMINATEDPHASE22017-07-262021-06-302021-06-30
NCT03201445Study to Evaluate the Testicular Safety of Filgotinib in Adult Males With Moderately to Severely Active Inflammatory Bowel DiseaseTERMINATEDPHASE22017-07-112023-10-242020-11-20
NCT03450720Pharmacokinetics of GLPG2737 in Male Subjects With Cystic FibrosisCOMPLETEDPHASE12017-06-282017-08-162017-08-16
NCT03311009A Study With GLPG1972 in Osteoarthritis SubjectsCOMPLETEDPHASE12017-05-152017-10-252017-10-25
NCT03143712Study to Assess Bioavailability of GLPG1690 Given as Oral Capsule or TabletCOMPLETEDPHASE12017-04-182017-06-142017-06-14
NCT03143725Study to Compare Bioavailability of GLPG1972 Given as 2 Different Tablet Formulations Versus an Oral SolutionCOMPLETEDPHASE12017-04-142017-06-062017-06-06
NCT03128606A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG3067 in Healthy Subjects.COMPLETEDPHASE12017-03-282018-02-202018-02-20
NCT03119649A Study to Evaluate Multiple Doses of GLPG2222 in Adult Subjects With Cystic FibrosisCOMPLETEDPHASE22017-03-182017-10-192017-10-19
NCT02914600Filgotinib in Long-Term Extension Study of Adults With Crohn's DiseaseTERMINATEDPHASE32017-03-172023-08-012023-08-01
NCT03101670A Study to Assess Efficacy and Safety of Filgotinib in Active Psoriatic ArthritisCOMPLETEDPHASE22017-03-092018-03-122018-03-12
NCT03117270A Study to Assess Efficacy and Safety of Filgotinib in Ankylosing SpondylitisCOMPLETEDPHASE22017-03-072018-07-022018-07-02
NCT03045523A Study to Evaluate GLPG2222 in Ivacaftor-treated Subjects With Cystic FibrosisCOMPLETEDPHASE22017-012017-08-112017-08-11
NCT03410979A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG2737 in Healthy SubjectsCOMPLETEDPHASE12016-11-252017-08-152017-08-15
NCT03214614A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG2451 in Healthy Male SubjectsCOMPLETEDPHASE12016-11-142017-08-252017-08-25
NCT02914561Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's DiseaseCOMPLETEDPHASE32016-10-312022-11-112022-11-11
NCT03102567This is a Study to Evaluate the Effect of Aging of Multiple Doses of GLPG1205 in Healthy SubjectsCOMPLETEDPHASE12016-10-182017-02-132017-02-13
NCT02851485Bioavailability Study With GLPG1972COMPLETEDPHASE12016-072016-082016-07
NCT02788721A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG2451 in Healthy Female SubjectsCOMPLETEDPHASE12016-04-142017-04-272017-04-27
NCT02739009First in Human of Single and Multiple Doses of MOR106COMPLETEDPHASE12016-042017-08-012017-08-01
NCT02738801Study to Assess Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties of GLPG1690 in Subjects With Idiopathic Pulmonary Fibrosis (IPF)COMPLETEDPHASE22016-032017-05-022017-05-02
NCT02707562Study of GLPG1837 in Subjects With Cystic Fibrosis (G551D Mutation)COMPLETEDPHASE22016-022016-112016-11
NCT02690519Study of GLPG1837 in Subjects With Cystic Fibrosis (S1251N Mutation)COMPLETEDPHASE22016-012016-092016-08
NCT02662452First-in-Human Single and Multiple Dose of GLPG2222COMPLETEDPHASE12016-012016-052016-04
NCT02612246First-in-Human Single and Multiple Dose of GLPG1972COMPLETEDPHASE12015-112016-072016-04
NCT02623296A Drug-drug Interaction Study Between GLPG1205 and a Cocktail of CYP450 Substrates in Healthy Male SubjectsCOMPLETEDPHASE12015-102016-022016-02
NCT02562859Oral Bioavailability of Solid Formulation of GLPG1837 With and Without FoodCOMPLETEDPHASE12015-092015-102015-10
NCT02562950A Phase I, Open Interaction Study Between GLPG1837 and Midazolam in Healthy Male SubjectsCOMPLETEDPHASE12015-092015-102015-10
NCT02337608Efficacy and Safety of GLPG1205 in Subjects With Active Ulcerative ColitisCOMPLETEDPHASE22014-122015-112015-09
NCT02325037First-in-Human Single and Multiple Dose of GLPG1837COMPLETEDPHASE12014-122015-092015-09
NCT02179502First-in-Human Single and Multiple Dose of GLPG1690COMPLETEDPHASE12014-062014-122014-11
NCT02162355Multiple Ascending Dose Study of GLPG0634 in Japanese and Caucasian Healthy SubjectsCOMPLETEDPHASE12014-062014-092014-09
NCT02143856Oral Bioavailability of Solid Formulation of GLPG1205 With and Without FoodCOMPLETEDPHASE12014-052014-072014-07
NCT02084199Study to Evaluate GLPG0634 in Subjects With Renal Impairment Compared to Healthy SubjectsCOMPLETEDPHASE12014-032014-072014-07
NCT02065700Long-term Follow-up Study of GLPG0634 in Active Rheumatoid Arthritis ParticipantsCOMPLETEDPHASE22014-02-252023-01-192023-01-19
NCT02048618Efficacy and Safety of GLPG0634 in Subjects With Active Crohn's DiseaseCOMPLETEDPHASE22014-022016-022015-11
NCT01894516Dose-finding Study of GLPG0634 as Monotherapy in Active Rheumatoid Arthritis (RA) Participants (DARWIN2)COMPLETEDPHASE22013-10-082015-05-292015-03-05
NCT01888874Dose-finding Study of GLPG0634 as add-on to Methotrexate in Active Rheumatoid Arthritis Participants (DARWIN1)COMPLETEDPHASE22013-07-172015-05-142015-02-18
NCT01915667Oral Bioavailability of Two Solid Formulations of GLPG0634COMPLETEDPHASE12013-072013-092013-09
NCT01887106First-in-Human Single and Multiple Dose of GLPG1205COMPLETEDPHASE12013-062013-102013-09
NCT01829321Safety, Efficacy, Pharmacokinetic and Pharmacodynamic Study of GLPG0974 in Subjects With Ulcerative ColitisCOMPLETEDPHASE22013-042014-042014-04
NCT01820806Investigation of the Pharmacokinetics and Metabolism of GLPG0634 in Healthy Male SubjectsCOMPLETEDPHASE12013-032013-042013-04
NCT01798979A Phase I, Open Interaction Study Between GLPG0634 and Midazolam in Healthy SubjectsCOMPLETEDPHASE12013-022013-042013-04
NCT01721980Multiple Ascending Dose Study of GLPG0974 in Healthy SubjectsCOMPLETEDPHASE12012-102013-022013-02
NCT01665924Single and Multiple Dose Pharmacokinetics of GLPG0634 in Elderly Healthy SubjectsCOMPLETEDPHASE12012-072012-102012-09
NCT01668641Dose-ranging Study With GLPG0634 in Methotrexate-refractory Active Rheumatoid Arthritis PatientsCOMPLETEDPHASE22012-052012-102012-09
NCT01580644Bioavailability Study of Prodrug of GLPG0187 in Healthy VolunteersCOMPLETEDPHASE12012-012012-032012-03
NCT01538420GLPG0492 PharmacodynamicsCOMPLETEDPHASE12012-012012-042012-03
NCT01496937First-in-Human Exploratory Single Ascending Dose of GLPG0974COMPLETEDPHASE12011-122012-022012-01
NCT01419990Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Oral Doses of GLPG0634 in Healthy SubjectsCOMPLETEDPHASE12011-082011-102011-10
NCT01397370Multiple Ascending Dose Study of GLPG0492 in Healthy SubjectsCOMPLETEDPHASE12011-072011-122011-12
NCT01384422Safety and Preliminary Efficacy of GLPG0634 in Methotrexate-refractory Active Rheumatoid Arthritis PatientsCOMPLETEDPHASE22011-062011-112011-11
NCT01336244GLPG0778: Multiple Ascending Oral Doses, Pharmacokinetic, Safety, and Pharmacodynamic StudyCOMPLETEDPHASE12011-042011-092011-08
NCT01313598GLPG0187: Safety, Tolerability and Pharmacokinetics in Patients With Solid TumorsCOMPLETEDPHASE12011-032013-062013-05
NCT01278095Oral Bioavailability of GLPG0555 in Different Solid FormulationsCOMPLETEDPHASE12011-012011-032011-02
NCT01278108First-in-Human Single Ascending and Multiple Dose of GLPG0778COMPLETEDPHASE12010-122011-052011-02
NCT01322451Oral Bioavailability of Two Solid Formulations of GLPG0259.COMPLETEDPHASE12010-112011-012010-12
NCT01211249GLPG0259 in Methotrexate-refractory Rheumatoid ArthritisCOMPLETEDPHASE22010-102011-042011-04
NCT01208753Pharmacokinetics/Pharmacodynamics (PK/PD) of Multiple Oral Doses of GLPG0555 in Healthy SubjectsCOMPLETEDPHASE12010-092011-022010-11
NCT01179581First-in-Human Single Ascending and Multiple Dose of GLPG0634COMPLETEDPHASE12010-082011-032011-03
NCT01130818First-in-Human Single Ascending Dose of GLPG0492COMPLETEDPHASE12010-052010-092010-08
NCT01039103Nanocort in Acute Exacerbation of Relapsing-Remitting Multiple Sclerosis (MS)TERMINATEDPHASE22009-122011-112011-11
NCT01023321First-in-Human Single Ascending and Multiple Dose of GLPG0555COMPLETEDPHASE12009-122010-052010-04
NCT01024517GLPG0259 Solid Formulation Bioavailability and Food EffectCOMPLETEDPHASE12009-112010-022009-12
NCT00989703GLPG0259 Multiple Ascending Dose and Methotrexate Drug-drug Interaction (DDI) in Healthy SubjectsCOMPLETEDPHASE12009-092010-012009-11
NCT00928343First-in-Human Single Ascending Subcutaneous (s.c.) Dose and Single Oral Dose of GLPG0187COMPLETEDPHASE12009-062009-122009-11
NCT00905138First-in-Human Single Ascending and Multiple Dose of GLPG0259COMPLETEDPHASE12009-032009-062009-06