Clinical Trials - XENE

NCT IDTitleStatusPhasesStart DateCompletion DatePrimary Completion Date
NCT07172516A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)RECRUITINGPHASE32025-08-082028-082028-06
NCT07076407A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)RECRUITINGPHASE32025-07-082027-072027-05
NCT06922110An Open-Label Study of Azetukalner in Major Depressive DisorderENROLLING_BY_INVITATIONPHASE32025-03-182027-032027-01
NCT06775379A Randomized Study of Azetukalner Versus Placebo in Major Depressive DisorderRECRUITINGPHASE32024-12-202026-102026-08
NCT05716100A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)RECRUITINGPHASE32023-05-092025-122025-08
NCT05718817An Open-label Study of XEN1101 in EpilepsyENROLLING_BY_INVITATIONPHASE32023-04-252028-092028-07
NCT05667142A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic SeizuresRECRUITINGPHASE32023-02-142027-062027-04
NCT05614063A Randomized Study of XEN1101 Versus Placebo in Focal-Onset SeizuresACTIVE_NOT_RECRUITINGPHASE32022-11-182026-022025-12
NCT05376150A Study to Evaluate the Safety, Tolerability and Efficacy of XEN1101 in Major Depressive DisorderCOMPLETEDPHASE22022-05-192023-10-162023-09-18
NCT04912856An Open-Label Extension of the Study XEN496 (Ezogabine) in Children With KCNQ2-DEETERMINATEDPHASE32021-08-172023-11-172023-11-17
NCT04952467Single-dose Mass Balance Recovery and Metabolite Profile and Identification of 14C-XEN1101COMPLETEDPHASE12021-07-142021-10-042021-10-04
NCT04639310XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic EncephalopathyTERMINATEDPHASE32021-03-292023-05-162023-05-16
NCT03796962A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal EpilepsyACTIVE_NOT_RECRUITINGPHASE22019-01-302028-102021-09-02
NCT03467100Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Oral Doses of XEN901COMPLETEDPHASE12018-02-192018-12-192018-12-19
NCT03468725Safety, Tolerability, Pharmacokinetics and Effects on Transcranial Magnetic Stimulation of Oral Doses of XEN1101COMPLETEDPHASE12018-02-132018-07-312018-07-31
NCT03340220Safety, Tolerability, and Pharmacokinetics (PK) of Single and Multiple Ascending Oral Doses of XEN1101.COMPLETEDPHASE12017-11-132021-11-262021-11-26
NCT02656043A Safety, Tolerability, Efficacy and Exposure Study of XEN801 Topical GelCOMPLETEDPHASE1, PHASE22015-09-172017-03-172017-02-16
NCT01486446Phase 2a, Exploratory Study to Evaluate the Safety, Efficacy, Tolerability and Pharmacokinetics of XPF-002 in Patients With Primary/Inherited ErythromelalgiaCOMPLETEDPHASE1, PHASE22011-122012-052012-04
NCT01195636A Crossover Study to Evaluate the Safety, Tolerability and Efficacy of XPF-002 in Subjects With Postherpetic Neuralgia (PHN)COMPLETEDPHASE22010-082011-032011-03
NCT01090622Study of XPF-001 in the Treatment of Pain From Primary/Inherited Erythromelalgia (IEM)COMPLETEDPHASE1, PHASE22010-042010-092010-08
NCT00954356Safety and Efficacy Study of XPF-001 to Treat Pain Following Wisdom Tooth ExtractionCOMPLETEDPHASE22009-092009-122009-11
NCT00813670Single and Multiple Ascending Dose Safety Study of XPF-001 in Healthy VolunteersCOMPLETEDPHASE12008-112009-072009-05