| NCT ID | Title | Status | Phases | Start Date | Completion Date | Primary Completion Date |
|---|---|---|---|---|---|---|
| NCT07108153 | Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Added to Trikafta | NOT_YET_RECRUITING | PHASE2 | 2025-10 | 2026-07 | 2026-07 |
| NCT07035990 | Safety, Tolerability, and Pharmacokinetics of Multiple Dose Combinations of SION-451 and Complementary Modulators SION-2222 and SION-109 in Healthy Participants. | RECRUITING | PHASE1 | 2025-07-23 | 2026-06 | 2026-06 |