Clinical Trials - PLX

NCT IDTitleStatusPhasesStart DateCompletion DatePrimary Completion Date
NCT05745727A Study to Evaluate the Safety, Tolerability, PK, and PD Properties of PRX-115 in Adult Volunteers With Elevated Uric Acid LevelsCOMPLETEDPHASE12023-03-232025-02-062024-08-26
NCT03180840Safety, Efficacy, & PK of PRX-102 in Patients With Fabry Disease Administered Intravenously Every 4 WeeksCOMPLETEDPHASE32017-07-102020-08-012020-08-01
NCT02921620Study to Evaluate the Safety and EffIcacy of PRX-102 on Gastrointestinal Symptoms in Naïve Fabry DiseaseWITHDRAWNPHASE32017-072018-072018-07
NCT03018730Safety and Efficacy of PRX-102 in Patients With Fabry Disease Currently Treated With REPLAGAL® (Agalsidase Alfa)COMPLETEDPHASE32017-05-172020-01-092019-12-17
NCT02768974Open Label Study to Assess Safety, PK and Explore Efficacy of OPRX-106 in Patients With Active Mild to Moderate Ulcerative ColitisUNKNOWNPHASE22016-092017-02
NCT02795676Study of the Safety and Efficacy of PRX-102 Compared to Agalsidase Beta on Renal FunctionCOMPLETEDPHASE32016-062022-072021-10
NCT02722122Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Exploratory Efficacy Parameters of AIR DNase™in Patients With Cystic Fibrosis Previously Treated With Pulmozyme®UNKNOWNPHASE22016-052017-02
NCT02605590Safety, Tolerability and Pharmacokinetics Study of AIR DNAse Administered by Inhalation to Healthy Adult VolunteersCOMPLETEDPHASE12015-122016-022016-02
NCT02107833Study to Evaluate the Safety and Pharmacokinetics of Oral OPRX-106 (TNFR-Fc Fusion Protein) in Healthy VolunteersCOMPLETEDPHASE12014-072014-122014-12
NCT02107846An Open-Label, Dose Escalation Study to Evaluate the Safety and the Pharmacokinetics of Oral PRX-112COMPLETEDPHASE22014-042015-122015-12
NCT01981720Extension Study of PRX-102 for up to 60 MonthsCOMPLETEDPHASE1, PHASE22014-01-162021-11-092020-08-26
NCT01747980Safety and Pharmacokinetics of Oral PRX-112 in Gaucher Disease PatientsCOMPLETEDPHASE12013-032014-032014-01
NCT01678898Dose-ranging Study of PRX-102 in Adult Fabry Disease PatientsCOMPLETEDPHASE1, PHASE22012-102016-03-062016-03-06
NCT01093859An Exploratory Phase 1 Microdose Study of PRX-105COMPLETEDEARLY_PHASE12010-032010-082010-05
NCT00258778Phase I Single Dose-Escalation Safety Study of Human Glucocerebrosidase (prGCD)COMPLETEDPHASE12005-112006-01