| NCT06977568 | A Study to Evaluate an Intra-Articular Injection of ZILRETTA Versus Triamcinolone Acetonide, Immediate Release in Subjects With Osteoarthritis of the Hip | RECRUITING | PHASE2 | 2025-07-25 | 2026-04 | 2026-04 |
| NCT06884865 | A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee | RECRUITING | PHASE2 | 2025-02-26 | 2032-03 | 2027-03 |
| NCT06340451 | Study to Assess the Efficacy and Safety of Iovera®° System in Subjects With Upper Extremity Spasticity | RECRUITING | PHASE3 | 2024-04-16 | 2026-03 | 2026-03 |
| NCT06271265 | Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery | RECRUITING | PHASE1 | 2024-03-29 | 2027-01 | 2027-01 |
| NCT06269705 | ZILRETTA in Subjects With Shoulder Osteoarthritis | RECRUITING | PHASE3 | 2024-02-05 | 2025-08 | 2025-08 |
| NCT05456490 | Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Pharmacodynamics of Liposomal Bupivacaine 13.3 Administered Via a Single Intrathecal Injection to Healthy Volunteers | COMPLETED | PHASE1 | 2023-04-18 | 2025-02-27 | 2025-02-27 |
| NCT05157841 | Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy | COMPLETED | PHASE3 | 2022-02-15 | 2022-08-17 | 2022-08-17 |
| NCT05139030 | Phase 3 Adductor Canal Block With EXPAREL in Subjects Undergoing Primary Unilateral Total Knee Arthroplasty | COMPLETED | PHASE3 | 2022-01-18 | 2022-07-11 | 2022-07-11 |
| NCT04826328 | Study to Evaluate the Safety and Tolerability of FX301 in Patients Undergoing Bunionectomy | COMPLETED | PHASE1 | 2021-03-15 | 2022-03-30 | 2022-01-11 |
| NCT04518462 | Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity Surgeries | COMPLETED | PHASE3 | 2020-10-20 | 2021-04-05 | 2021-04-05 |
| NCT04191031 | Study to Evaluate Iovera®° in Adult Patients Undergoing Total Knee Arthroplasty | TERMINATED | NA | 2020-09-30 | 2022-07-12 | 2022-05-13 |
| NCT03954639 | Phase 3, Randomized, Double Blinded, Active Controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL Admixed With Bupi vs. Bupi Only Administered as Combined Sciatic and Adductor Canal Nerve Block for Postsurgical Analgesia in Lower Extremity Surgeries | WITHDRAWN | PHASE3 | 2020-06-15 | 2020-09 | 2020-09 |
| NCT04173611 | Evaluation of Safety, Pharmacokinetics and Pharmacodynamics of EXPAREL® Administered Via a Single Intrathecal Injection to Healthy Volunteers | TERMINATED | PHASE1 | 2020-06-08 | 2020-12-07 | 2020-12-07 |
| NCT04119687 | Study to Evaluate the Safety and Tolerability of FX201 in Patients with Osteoarthritis of the Knee | ACTIVE_NOT_RECRUITING | PHASE1 | 2020-03-02 | 2026-11-28 | 2023-11-28 |
| NCT04293809 | Study to Evaluate the Pharmacokinetics and Safety of EXPAREL Administered as a Pectoral Plane Block in Women Undergoing Breast Augmentation | COMPLETED | PHASE1 | 2019-12-19 | 2020-01-29 | 2020-01-15 |
| NCT04160091 | Study to Evaluate the Efficacy and Safety of FX006 in Patients With Glenohumeral Osteoarthritis or Shoulder Adhesive Capsulitis | TERMINATED | PHASE2 | 2019-11-07 | 2020-06-15 | 2020-06-15 |
| NCT03955458 | EXPAREL Facia Iliaca Compartment Block for Intertrochanteric Hip Fracture | WITHDRAWN | PHASE4 | 2019-08-26 | 2020-05 | 2020-05 |
| NCT03927911 | Phase 4 Study in Adult Subjects Undergoing Posterior Lumbar Spine Surgeries | TERMINATED | PHASE4 | 2019-07-31 | 2020-08-04 | 2020-08-04 |
| NCT04065074 | Study to Evaluate a Procedure for Intra-articular Injection of FX006 in Patients With Osteoarthritis of the Hip | COMPLETED | PHASE2 | 2019-07-30 | 2019-12-30 | 2019-10-11 |
| NCT04002089 | Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety, of EXPAREL Administered as Sciatic Nerve Block (In Popliteal Fossa), for Postsurgical Analgesia in Subjects Undergoing Bunionectomy | COMPLETED | PHASE1 | 2019-07-26 | 2019-12-02 | 2019-12-02 |
| NCT03909516 | Evaluate the Iovera° Device in Treating Pain Associated With Anterior Cruciate Ligament Reconstruction | WITHDRAWN | NA | 2019-05-01 | 2019-05-01 | 2019-05-01 |
| NCT03682302 | Multicenter Study for Pediatric Subjects Evaluating Pharmacokinetics and Safety of EXPAREL | COMPLETED | PHASE3 | 2019-04-02 | 2019-09-24 | 2019-08-30 |
| NCT03853694 | Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Undergoing Elective Cesarean Section | COMPLETED | PHASE4 | 2019-03-04 | 2020-01-16 | 2020-01-09 |
| NCT03793010 | Study to Evaluate the Efficacy and Safety of FX006 in Patients With Hip Osteoarthritis | TERMINATED | PHASE3 | 2018-12-12 | 2019-08-07 | 2019-08-07 |
| NCT03688477 | Iovera° to Treat Pain Associated With ACL Reconstruction and Rehabilitation | WITHDRAWN | NA | 2018-10 | 2019-06 | 2019-03 |
| NCT03428984 | Study in Adult Subjects Undergoing Posterolateral Thoracotomy | TERMINATED | PHASE1 | 2018-05-03 | 2018-09-28 | 2018-09-28 |
| NCT03529942 | Study to Evaluate the Effect of FX006 on Synovial Inflammation in Patients With OA of the Knee | COMPLETED | PHASE3 | 2018-04-24 | 2020-03-09 | 2019-11-08 |
| NCT03485014 | Study in Pediatric Subjects Evaluating Pharmacokinetics and Safety of EXPAREL | COMPLETED | PHASE1 | 2018-04-10 | 2019-02-12 | 2019-02-12 |
| NCT03382262 | Study to Compare Exposure of TA Following Administration of FX006 or TAcs in Patients With OA of the Shoulder or Hip | COMPLETED | PHASE2 | 2017-12-18 | 2018-10-09 | 2018-10-09 |
| NCT03378076 | Study to Compare Exposure of TA Following Administration of Either FX006 or TAcs in Patients With Bilateral Knee OA | COMPLETED | PHASE2 | 2017-12-06 | 2018-03-14 | 2018-03-14 |
| NCT03327220 | Treatment With Iovera° for Total Knee Arthroplasty (TKA) Post-Operative Pain | COMPLETED | NA | 2017-11-06 | 2019-03-27 | 2019-03-27 |
| NCT03176459 | Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration Into the TAP vs. Bupivacaine Alone in Subjects Undergoing Elective C-Sections | COMPLETED | PHASE4 | 2017-06-01 | 2018-12-04 | 2018-11-20 |
| NCT03015961 | Phase 4, Controlled Study in Adult Subjects Undergoing Primary, 1-2 Level, Open Lumbar Spinal Fusion Surgery | TERMINATED | PHASE4 | 2017-02-21 | 2017-10-30 | 2017-10-30 |
| NCT03046446 | Study to Assess the Safety of Repeat Administration of FX006 Administered to Patients With Osteoarthritis of the Knee | COMPLETED | PHASE3 | 2017-02-20 | 2018-07-19 | 2018-07-19 |
| NCT02985762 | PK Study of EXPAREL in Subjects Undergoing Open Spinal Fusion or Reconstructive Surgery | COMPLETED | PHASE1 | 2016-12 | 2017-09 | 2017-09 |
| NCT02922582 | Study of Local Administration of DepoTXA for Reduced Postsurgical Bleeding in Subjects Undergoing TKA | TERMINATED | PHASE2 | 2016-10-28 | 2017-11-27 | 2017-11-27 |
| NCT02713178 | Efficacy, Safety, and Pharmacokinetics of Femoral Nerve Block With EXPAREL in Total Knee Arthroplasty | COMPLETED | PHASE3 | 2016-06-03 | 2017-06-30 | 2017-06-30 |
| NCT02713230 | Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block With EXPAREL in Shoulder Surgery | COMPLETED | PHASE3 | 2016-05-09 | 2017-07-07 | 2017-07-07 |
| NCT02713490 | Local Infiltration Analgesia With and Without EXPAREL Following Total Knee Arthroplasty | COMPLETED | PHASE4 | 2016-04-18 | 2017-02-08 | 2017-02-08 |
| NCT02762370 | Study to Assess the Effects of FX006 on Blood Glucose in Patients With OA of the Knee and Type 2 Diabetes | COMPLETED | PHASE2 | 2016-04 | 2016-11 | 2016-10 |
| NCT02637323 | Study to Characterize the PK and Local Extent and Duration of Exposure From FX006 in Patients With OA of the Knee | COMPLETED | PHASE2 | 2015-11 | 2016-09 | 2016-09 |
| NCT02517905 | Evaluation of EXPAREL for Prolonged Postsurgical Analgesia in Subjects Undergoing Third Molar Extraction | COMPLETED | PHASE3 | 2015-08 | 2016-01 | 2016-01 |
| NCT02353754 | Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP in Subjects Undergoing Cesarean Section | TERMINATED | PHASE4 | 2015-05 | 2015-07 | 2015-06 |
| NCT02468583 | Proof of Concept Study Comparing FX006 to Kenalog®-40 in Patients With Post-Traumatic Osteoarthritis of the Knee | TERMINATED | PHASE2 | 2015-02 | 2016-07 | 2016-07 |
| NCT02357459 | Study of FX006 for the Treatment of Pain in Patients With Osteoarthritis of the Knee | COMPLETED | PHASE3 | 2015-01 | 2016-01 | 2016-01 |
| NCT02284113 | A Randomized, Study to Evaluate the Iovera° Device in Treating Pain Associated With Total Knee Arthroplasty | COMPLETED | NA | 2014-12 | 2016-06 | 2016-05 |
| NCT02284386 | Pharmacokinetics and Safety of Bupivacaine HCl Spinal Block and EXPAREL Local Infiltration in Total Knee Arthroplasty | COMPLETED | PHASE4 | 2014-12 | 2015-03 | 2015-03 |
| NCT02260921 | Study to Evaluate the Iovera° Device for Temporary Relief From Knee Pain | COMPLETED | NA | 2014-10-20 | 2016-05-31 | 2016-02 |
| NCT02255500 | EXPAREL Infiltration in Subjects Undergoing Femoral Nerve Block With Bupivacaine HCl for Total Knee Arthroplasty | COMPLETED | PHASE4 | 2014-09 | 2015-03 | 2015-03 |
| NCT02210247 | Safety and Pharmacokinetics Study of Redosing EXPAREL in Healthy Volunteers | COMPLETED | PHASE1 | 2014-08 | 2014-09 | 2014-09 |
| NCT02199574 | Pharmacokinetic Evaluation of EXPAREL in Adults Undergoing Tonsillectomy | COMPLETED | PHASE4 | 2014-08 | 2015-06 | 2015-04 |
| NCT02116972 | Study of FX006 vs Normal Saline in Patients With Osteoarthritis of the Knee | COMPLETED | PHASE2 | 2014-04 | 2015-11 | 2015-11 |
| NCT02003365 | Study to Characterize the Local Duration of Exposure From FX006 in Patients With Osteoarthritis of the Knee | COMPLETED | PHASE2 | 2013-11 | 2014-04 | 2014-04 |
| NCT01950065 | Effectiveness and Safety Study of the Iovera Device for the Temporary Reduction in the Appearance of Forehead Wrinkles | COMPLETED | NA | 2013-09 | 2014-10 | 2014-10 |
| NCT01919190 | EXPAREL Administered by Infiltration Into the TAP for Prolonged Postsurgical Analgesia in Lower Abdominal Surgeries | TERMINATED | PHASE4 | 2013-08 | 2014-02 | 2013-12 |
| NCT01863901 | Study Evaluating Treatment of Upper Limb Spasticity Using the Cryo-Touch III Device | COMPLETED | NA | 2013-04 | 2013-10 | 2013-07 |
| NCT01802411 | Intercostal Nerve Block With Liposome Bupivacaine in Subjects Undergoing Posterolateral Thoracotomy | COMPLETED | PHASE3 | 2012-12 | 2013-06 | 2013-06 |
| NCT02142829 | Pain Control in Bariatric Patients: EXPAREL(R) vs. the On-Q(R) Pain Ball | COMPLETED | PHASE4 | 2012-11 | 2013-03 | 2013-03 |
| NCT01753778 | Study Evaluating Treatment of Forefoot Pain Related to Nerve Entrapment Using the Cryo-Touch III Device | COMPLETED | NA | 2012-11 | 2013-08 | 2013-05 |
| NCT01753765 | Study Evaluating the Treatment of Occipital Neuralgia | COMPLETED | NA | 2012-10 | 2014-07 | 2013-12 |
| NCT01704157 | A Prospective Study Evaluating the Treatment of Knee Osteoarthritis With the Cryo-Touch III Device | COMPLETED | NA | 2012-09 | 2013-07 | 2013-04 |
| NCT01683071 | Femoral Nerve Block With Liposome Bupivacaine for Postsurgical Analgesia Following Total Knee Arthroplasty | COMPLETED | PHASE2, PHASE3 | 2012-09 | 2013-12 | 2013-12 |
| NCT01919606 | EXPAREL Administered Into the TAP for Analgesia in Subjects Undergoing Open Total Abdominal Hysterectomy | TERMINATED | PHASE4 | 2012-08 | 2012-10 | 2012-10 |
| NCT01487200 | Pharmacokinetic and Pharmacodynamic Study of FX006 in Patients With Osteoarthritis of the Knee | COMPLETED | PHASE2 | 2012-07 | 2012-11 | 2012-11 |
| NCT01487161 | Study of FX006 in Patients With Osteoarthritis of the Knee | COMPLETED | PHASE2 | 2012-06 | 2013-04 | 2013-04 |
| NCT01681745 | Probe Configuration and Time-Temperature Dose Ranging for Understanding of Skin Lesion Effects | COMPLETED | NA | 2012-06-01 | 2015-04-01 | 2015-04-01 |
| NCT01507233 | A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302 | TERMINATED | PHASE4 | 2012-05 | 2012-07 | 2012-07 |
| NCT01801124 | EXPAREL Infiltrated Into the TAP for Postoperative Analgesia in Unilateral Abdominal Hernia Repair | COMPLETED | PHASE4 | 2012-04 | 2012-12 | 2012-12 |
| NCT01582490 | Study of EXPAREL in Patients Undergoing Breast Augmentation | COMPLETED | PHASE4 | 2012-04 | 2012-11 | 2012-11 |
| NCT01582477 | TAP-patients With Robotic Assisted Lap Prostatectomy | COMPLETED | PHASE4 | 2012-03 | 2012-07 | 2012-05 |
| NCT01509638 | A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B501 | COMPLETED | PHASE4 | 2012-03 | 2012-10 | 2012-10 |
| NCT01507220 | A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301 | TERMINATED | PHASE4 | 2012-03 | 2012-07 | 2012-07 |
| NCT01509807 | A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B504 | COMPLETED | PHASE4 | 2012-01 | 2012-10 | 2012-10 |
| NCT02058290 | A Health Economic Trial in Adult Patients Undergoing Laparoscopic Colectomy | TERMINATED | PHASE4 | 2011-12 | 2013-02 | 2012-09 |
| NCT01507246 | Adult Patients Undergoing Open Colectomy MA402S23B303 | COMPLETED | PHASE4 | 2011-12 | 2012-08 | 2012-07 |
| NCT01447342 | A Study to Evaluate the Safety and Effectiveness of the Cryo-Touch II Device for the Treatment of Forehead and/or Glabellar Lines | COMPLETED | PHASE2, PHASE3 | 2011-09 | 2012-08 | 2012-01 |
| NCT01379365 | Cryo-Touch III Refinement Study Investigational Plan | COMPLETED | PHASE2, PHASE3 | 2011-06 | 2014-12 | 2014-12 |
| NCT01291914 | Study of FX005 for the Treatment of Pain in Patients With Osteoarthritis of the Knee | COMPLETED | PHASE1, PHASE2 | 2010-12 | 2012-03 | 2012-01 |
| NCT01167140 | Cryo-Touch II for the Treatment of Wrinkles | COMPLETED | PHASE2, PHASE3 | 2010-07 | 2011-04 | 2011-01 |
| NCT00890721 | Study of Pain Control in Hemorrhoidectomy | COMPLETED | PHASE3 | 2009-05 | 2009-11 | 2009-11 |
| NCT00890682 | Study of Postoperative Analgesia in Bunionectomy | COMPLETED | PHASE3 | 2009-04 | 2009-11 | 2009-11 |
| NCT00842062 | Study of the MyoScience Tissue Remodeling Device for Facial Rejuvenation | COMPLETED | PHASE1, PHASE2 | 2009-02 | 2012-01 | 2012-01 |
| NCT00812305 | Hepatic Impairment Study: Pharmacokinetics in Healthy and Hepatically Impaired Subjects | COMPLETED | PHASE1 | 2009-01 | 2009-08 | 2009-08 |
| NCT00807209 | Dose Finding Posterolateral Thoracotomy Study | TERMINATED | PHASE2 | 2008-12 | 2009-02 | 2009-02 |
| NCT00813111 | Phase 3 Study of Local Administration of SKY0402 for Postoperative Analgesia in Subject Undergoing Breast Augmentation | TERMINATED | PHASE3 | 2008-11 | 2009-02 | 2009-02 |
| NCT00806806 | Evaluate the Onset of Action of SKY0402 Following Local Infiltration in Healthy Volunteers | COMPLETED | PHASE1 | 2008-10 | 2009-02 | 2009-02 |
| NCT00744848 | Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy | COMPLETED | PHASE3 | 2008-08 | 2009-02 | 2009-02 |
| NCT00745290 | A Phase 3 Study to Evaluate the Safety and Efficacy of SKY0402 in Subjects Undergoing Total Knee Arthroplasty | COMPLETED | PHASE3 | 2008-08 | 2009-02 | 2009-01 |
| NCT01206608 | Evaluation of the Safety and Efficacy of a Single Dose of SKY0402 in Subjects Undergoing Augmentation Mammoplasty | COMPLETED | PHASE2 | 2008-03 | 2008-12 | 2008-08 |
| NCT00529126 | Phase 2 Dose-Ranging Study of SKY0402 for Prolonged Postoperative Analgesia in Subject Undergoing Hemorrhoidectomy | COMPLETED | PHASE2 | 2007-09 | 2008-07 | 2007-12 |
| NCT00485693 | Dose-Ranging Study for Prolonged Postoperative Analgesia in Subject Undergoing Total Knee Arthroplasty | COMPLETED | PHASE2 | 2007-06 | 2009-08 | 2009-08 |
| NCT00485667 | Phase 1 Thorough QT Study in Young Healthy Volunteers | COMPLETED | PHASE1 | 2007-06 | 2007-08 | 2007-08 |
| NCT00485433 | Dose-ranging Study for Postoperative Analgesia in Subjects Undergoing Primary Unilateral Inguinal Hernia Repair | COMPLETED | PHASE2 | 2007-06 | 2008-08 | 2007-12 |
| NCT01206595 | Safety, Efficacy, and Pharmacokinetics of SKY0402 Administered as a Nerve Block in Subjects Undergoing Bunionectomy | COMPLETED | PHASE2 | 2005-03 | 2006-12 | 2006-03 |
| NCT01203644 | Evaluation of the Safety, Efficacy, and Pharmacokinetics of SKY0402 in Subjects Undergoing Inguinal Hernia Repair | COMPLETED | PHASE2 | 2004-12 | 2006-12 | 2006-01 |
| NCT00029523 | DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor | COMPLETED | PHASE4 | 2001-04 | 2004-11 | |