| NCT06495918 | Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular Degeneration | ACTIVE_NOT_RECRUITING | PHASE3 | 2024-11-27 | 2027-01-08 | 2027-01-08 |
| NCT06223958 | Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration | ACTIVE_NOT_RECRUITING | PHASE3 | 2024-01-29 | 2027-09-27 | 2026-04-29 |
| NCT05814757 | OTX-DED for the Short-term Treatment of the Symptoms of Dry Eye Disease (DED) | COMPLETED | PHASE2 | 2023-05-11 | 2024-05-22 | 2024-05-22 |
| NCT05695417 | Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-TKI in Subjects With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy | ACTIVE_NOT_RECRUITING | PHASE1 | 2023-01-15 | 2024-12 | 2024-01 |
| NCT05335122 | A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT) | COMPLETED | PHASE2 | 2022-03-16 | 2025-01-24 | 2024-01-24 |
| NCT04989699 | Study Evaluating the Treatment of OTX-TKI for Subjects With Neovascular Age-related Macular Degeneration | COMPLETED | PHASE1 | 2021-07-28 | 2023-12-18 | 2023-02-06 |
| NCT04945824 | A Human Factors Study to Evaluate a Novel Intracanalicular Insertion Device in Healthy Subjects | TERMINATED | EARLY_PHASE1 | 2021-06-01 | 2022-11-01 | 2022-11-01 |
| NCT04747977 | To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Signs and Symptoms of Dry Eye Disease | COMPLETED | PHASE2 | 2021-02-12 | 2021-09-22 | 2021-08-11 |
| NCT04539548 | A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract | COMPLETED | PHASE3 | 2020-09-04 | 2023-12-21 | 2023-12-21 |
| NCT04362670 | Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-CSI in Subjects With Dry Eye Disease. | COMPLETED | PHASE1, PHASE2 | 2020-04-23 | 2021-08-11 | 2021-08-11 |
| NCT04050865 | A Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Allergic Conjunctivitis | COMPLETED | PHASE3 | 2019-08-05 | 2020-02-28 | 2020-02-28 |
| NCT03630315 | CLN-0046: Treatment of AMD Subjects With OTX-TKI | COMPLETED | PHASE1 | 2019-02-18 | 2024-01-10 | 2024-01-10 |
| NCT04061044 | A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert | COMPLETED | PHASE3 | 2018-07-10 | 2020-09-22 | 2020-02-10 |
| NCT04360174 | CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular Hypertension | COMPLETED | PHASE1 | 2018-04-25 | 2021-05-24 | 2021-05-24 |
| NCT02914509 | Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT | COMPLETED | PHASE3 | 2016-11-07 | 2019-03-30 | 2019-03-30 |
| NCT02736175 | OTX-15:003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammation and Pain After Cataract Surgery | COMPLETED | PHASE3 | 2015-10 | 2016-07 | 2016-05 |
| NCT02988882 | OTX-15-002: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis | COMPLETED | PHASE3 | 2015-06 | 2016-04-27 | 2016-04-27 |
| NCT02445326 | OTX-14-007: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis | COMPLETED | PHASE3 | 2015-04 | 2015-09 | 2015-08 |
| NCT02468700 | OTX-14-006: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Dry Eye | COMPLETED | PHASE2 | 2015-01 | 2015-11 | 2015-08 |
| NCT02312544 | Phase 2b Study Evaluating Safety and Efficacy of OTX-TP Compared to Timolol Drops in the Treatment of Subjects With Open Angle Glaucoma or Ocular Hypertension | COMPLETED | PHASE2 | 2014-11 | 2015-12 | 2015-09 |
| NCT02089113 | OTX-14-003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammation and Pain After Cataract Surgery | COMPLETED | PHASE3 | 2014-04 | 2015-03 | 2015-01 |
| NCT02062905 | OTX-14-001: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis | COMPLETED | PHASE2 | 2014-03 | 2014-11 | 2014-08 |
| NCT02034019 | Phase 3 Study Evaluating Safety and Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery | COMPLETED | PHASE3 | 2014-02 | 2015-02 | 2014-12 |
| NCT01845038 | Multi-Arm Feasibility Study Evaluating OTX-TP Compared to Timolol in Treatment of Subjects With Open Angle Glaucoma | COMPLETED | PHASE1 | 2013-04 | 2014-05 | 2014-03 |
| NCT01800175 | Non-Significant Risk Feasibility Study to Assess Retention and Replacement of the OTX Punctum Plug | UNKNOWN | PHASE1 | 2013-02 | | 2016-12 |
| NCT01666210 | Phase II Study Evaluating Safety/Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery | COMPLETED | PHASE2 | 2012-10 | 2013-08 | 2013-08 |
| NCT01498224 | ReSure Sealant Pivotal Study | COMPLETED | PHASE3 | 2011-12 | 2012-11 | 2012-11 |
| NCT00774228 | I-ZIP Ocular Bandage Pivotal Study | COMPLETED | NA | 2008-10 | 2009-08 | 2009-07 |