| NCT04761198 | A Study of Etigilimab and Nivolumab in Participants With Locally Advanced or Metastatic Tumors | COMPLETED | PHASE1, PHASE2 | 2021-03-23 | 2023-10-30 | 2023-10-30 |
| NCT03636347 | A 12-week Study Treating Participants Who Have alpha1-antitrypsin-related COPD With Alvelestat (MPH966) or Placebo. | COMPLETED | PHASE2 | 2018-10-29 | 2022-03-30 | 2022-03-02 |
| NCT03498170 | The Effect of Itraconazole on BCT197 Exposure in Healthy Male Participants | COMPLETED | PHASE1 | 2018-03-19 | 2018-05-09 | 2018-05-03 |
| NCT03295942 | A Study of OMP-336B11 in Subjects With Locally Advanced or Metastatic Tumors | TERMINATED | PHASE1 | 2017-09-12 | 2019-07-04 | 2019-07-04 |
| NCT03119428 | A Study of OMP-313M32 in Subjects With Locally Advanced or Metastatic Solid Tumors | TERMINATED | PHASE1 | 2017-05-02 | 2019-05-15 | 2019-05-15 |
| NCT03031691 | A Study of Brontictuzumab With Chemotherapy for Subjects With Previously Treated Metastatic Colorectal Cancer | COMPLETED | PHASE1 | 2017-01 | 2017-09 | 2017-05 |
| NCT03030287 | A Phase 1b Study of OMP-305B83 Plus Paclitaxel in Subjects With Ovarian, Peritoneal or Fallopian Tube Cancer | COMPLETED | PHASE1 | 2016-12 | 2020-04 | 2020-04 |
| NCT03035253 | A Study of OMP-305B83 in Subjects With Metastatic Colorectal Cancer | TERMINATED | PHASE1 | 2016-12 | 2018-12 | 2018-09 |
| NCT02908074 | A 6 Month Safety Extension Study of MBGS205 | COMPLETED | PHASE2 | 2016-11-15 | 2018-11-21 | 2018-09-08 |
| NCT02926326 | The Effect of Azithromycin on BCT197 Exposure in Healthy Male Volunteers | COMPLETED | PHASE1 | 2016-09 | 2016-10 | 2016-10 |
| NCT02700919 | Efficacy and Safety of BCT197 in Subjects With Acute Respiratory Exacerbations of Chronic Obstructive Pulmonary Disease | COMPLETED | PHASE2 | 2016-08-01 | 2017-11-28 | 2017-11-08 |
| NCT02730169 | Safety and Efficacy of BGS649 in Male Obese Subjects With Hypogonadotropic Hypogonadism | COMPLETED | PHASE2 | 2016-05-12 | 2018-05-19 | 2018-02-15 |
| NCT02722954 | A Phase 1b Study of Demcizumab Plus Pembrolizumab in Locally Advanced or Metastatic Solid Tumors | COMPLETED | PHASE1 | 2016-01 | 2017-05-19 | 2017-05-10 |
| NCT02482441 | A Phase 1a/b Dose Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of OMP-131R10 | COMPLETED | PHASE1 | 2015-07-16 | 2018-03-28 | 2018-01-26 |
| NCT02289898 | Study of Gemcitabine, Abraxane® Plus Placebo Versus Gemcitabine, Abraxane® Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With 1st-Line Metastatic Pancreatic Ductal Adenocarcinoma | COMPLETED | PHASE2 | 2015-04-20 | 2017-09 | 2017-05 |
| NCT02259582 | A Study of Carboplatin, Pemetrexed Plus Placebo vs Carboplatin, Pemetrexed Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With Non-Squamous Non-Small Cell Lung Cancer | COMPLETED | PHASE2 | 2015-02 | 2017-04-07 | 2017-04-07 |
| NCT02298387 | A Phase 1 Study of OMP-305B83 in Subjects With Solid Tumors | COMPLETED | PHASE1 | 2014-12-22 | 2017-09-08 | 2017-05-23 |
| NCT02092363 | Dose Escalation Study of OMP-54F28 in Combination With Paclitaxel and Carboplatin in Patients With Recurrent Platinum-Sensitive Ovarian Cancer | COMPLETED | PHASE1 | 2014-01 | 2017-12 | 2017-10 |
| NCT02069145 | Dose Escalation Study of OMP-54F28 in Combination With Sorafenib in Patients With Hepatocellular Cancer | COMPLETED | PHASE1 | 2014-01 | 2017-07 | 2017-05 |
| NCT02050178 | Dose Escalation Study of OMP-54F28 in Combination With Nab-Paclitaxel and Gemcitabine in Patients With Previously Untreated Stage IV Pancreatic Cancer | COMPLETED | PHASE1 | 2013-11 | 2017-06-15 | 2017-06-15 |
| NCT01973309 | A Study of Vantictumab (OMP-18R5) in Combination With Paclitaxel in Locally Recurrent or Metastatic Breast Cancer | COMPLETED | PHASE1 | 2013-09 | 2017-12 | 2017-06 |
| NCT02005315 | A Study of Vantictumab (OMP-18R5) in Combination With Nab-Paclitaxel and Gemcitabine in Previously Untreated Stage IV Pancreatic Cancer | COMPLETED | PHASE1 | 2013-09 | 2017-11 | 2017-10 |
| NCT01957007 | A Study of Vantictumab (OMP-18R5) in Combination With Docetaxel in Patients With Previously Treated NSCLC | COMPLETED | PHASE1 | 2013-09 | 2017-06 | 2016-12 |
| NCT01952249 | A Study of Demcizumab Plus Paclitaxel in Subjects With Platinum Resistant Ovarian | TERMINATED | PHASE1 | 2013-08-05 | 2016-07-12 | 2016-05-10 |
| NCT01778439 | A Dose Escalation Study of OMP-52M51 in Subjects With Solid Tumors | COMPLETED | PHASE1 | 2013-02 | 2016-07 | 2016-07 |
| NCT01647828 | A Phase 1b/2 Study of OMP-59R5 (Tarextumab) in Combination With Nab-Paclitaxel and Gemcitabine in Subjects With Previously Untreated Stage IV Pancreatic Cancer | COMPLETED | PHASE1, PHASE2 | 2012-10 | 2016-04 | 2016-04 |
| NCT01703572 | A Dose Escalation Study of OMP-52M51 in Subjects With Lymphoid Malignancies | COMPLETED | PHASE1 | 2012-10 | 2016-01 | 2016-01 |
| NCT01608867 | A Dose Escalation Study of OMP-54F28 in Subjects With Solid Tumors | COMPLETED | PHASE1 | 2012-06 | 2017-06 | 2016-08 |
| NCT01859741 | A Phase 1b/2 Study of OMP-59R5 (Tarextumab) in Combination With Etoposide and Platinum Therapy | TERMINATED | PHASE1, PHASE2 | 2012-01-07 | 2017-05-08 | 2017-04-18 |
| NCT01336959 | Safety & Efficacy of BCT197 in Patients Undergoing Cardiac Surgery | TERMINATED | PHASE2 | 2011-09 | 2013-11 | 2013-11 |
| NCT01345201 | A Dose Escalation Study of OMP-18R5 in Subjects With Solid Tumors | COMPLETED | PHASE1 | 2011-05 | 2014-05 | 2014-05 |
| NCT01332097 | Safety & Efficacy of BCT197A2201 in COPD Patients Presenting With an Exacerbation | COMPLETED | PHASE2 | 2011-03 | 2013-05 | 2013-05 |
| NCT01277146 | A Dose Escalation Study of OMP-59R5 in Subjects With Solid Tumors | COMPLETED | PHASE1 | 2010-12 | 2013-05 | 2013-03 |
| NCT01189942 | A Study of FOLFIRI Plus OMP-21M18 as 1st or 2nd-line Treatment in Subjects With Metastatic Colorectal Cancer | COMPLETED | PHASE1 | 2010-09 | 2011-02 | 2011-02 |
| NCT01189968 | A Study of Carboplatin and Pemetrexed Plus Demcizumab (OMP-21M18) in Subjects With Non-Squamous Non-Small Cell Lung Cancer | COMPLETED | PHASE1 | 2010-09 | 2016-09 | 2016-09 |
| NCT01200862 | Safety and Efficacy of BGS649 in Obese, Hypogonadotropic Hypogonadal Men | TERMINATED | PHASE2 | 2010-08 | 2012-08 | 2012-08 |
| NCT01189929 | A Study of Gemcitabine and Demcizumab (OMP-21M18) With or Without Abraxane® as 1st-line Treatment in Subjects With Locally Advanced or Metastatic Pancreatic Cancer | COMPLETED | PHASE1 | 2010-08 | 2016-12 | 2016-12 |
| NCT01190475 | BGS649 Monotherapy in Moderate to Severe Endometriosis Patients | COMPLETED | PHASE2 | 2010-07 | 2011-09 | 2011-09 |
| NCT01116440 | A Safety & Efficacy Study of BGS649 in Women With Refractory Endometriosis | TERMINATED | PHASE2 | 2010-04-15 | 2012-03-21 | 2011-07 |
| NCT00744562 | A Phase 1 Dose Escalation Study of OMP-21M18 in Subjects With Solid Tumors | COMPLETED | PHASE1 | 2008-08 | 2012-01 | 2011-11 |