Clinical Trials - MGNX

NCT IDTitleStatusPhasesStart DateCompletion DatePrimary Completion Date
NCT06730347A Study of Lorigerlimab in Participants With Advanced Solid TumorsRECRUITINGPHASE22025-05-012027-082027-02
NCT06723236A Study of MGC028 in Participants With Advanced Solid TumorsRECRUITINGPHASE12025-02-132027-042026-11
NCT06242470A Study of MGC026 in Participants With Advanced Solid TumorsRECRUITINGPHASE12024-03-062028-102028-05
NCT05848011A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-Resistant Prostate CancerACTIVE_NOT_RECRUITINGPHASE22023-09-282027-092026-09
NCT05551117A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid TumorsCOMPLETEDPHASE22023-06-132025-01-232024-07-04
NCT05261191A Study of MGD020 Alone or Combined With MGD014 in Persons With HIV-1 on Antiretroviral TherapyCOMPLETEDPHASE12022-09-262024-05-292024-05-29
NCT05362773A Study of MGD024 in Patients With Relapsed or Refractory Hematologic MalignanciesRECRUITINGPHASE12022-07-132027-052026-11
NCT05293496A Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid TumorsACTIVE_NOT_RECRUITINGPHASE12022-04-192025-082025-06-24
NCT04634825Enoblituzumab Plus Retifanlimab or Tebotelimab in Head and Neck CancerTERMINATEDPHASE22021-03-172022-07-292022-07-29
NCT04129320Enoblituzumab Plus MGA012 or MGD013 in Squamous Cell Carcinoma of the Head and NeckWITHDRAWNPHASE2, PHASE32019-102022-102020-10
NCT04082364Combination Margetuximab, Retifanlimab, Tebotelimab, and Chemotherapy Phase 2/3 Trial in HER2+ Gastric/GEJ CancerCOMPLETEDPHASE2, PHASE32019-09-302025-03-252024-01-15
NCT03761017MGD019 DART® Protein in Unresectable/Metastatic CancerCOMPLETEDPHASE12018-12-122025-01-272024-08-29
NCT03729596MGC018 With or Without MGA012 in Advanced Solid TumorsTERMINATEDPHASE1, PHASE22018-11-212023-03-182023-03-18
NCT03570918MGD014 in HIV-Infected Individuals on Suppressive Antiretroviral TherapyCOMPLETEDPHASE12018-09-252021-09-282021-09-28
NCT03531632MGD007 Combined With MGA012 in Relapsed/Refractory Metastatic Colorectal CancerCOMPLETEDPHASE1, PHASE22018-06-042020-02-082020-02-08
NCT03406949MGD009/MGA012 Combination in Relapsed/Refractory CancerCOMPLETEDPHASE12018-02-272022-04-272022-04-27
NCT03219268A Study of MGD013 in Patients With Unresectable or Metastatic NeoplasmsCOMPLETEDPHASE12017-08-182023-02-082023-02-08
NCT02982941Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid TumorsCOMPLETEDPHASE12016-122019-05-222019-05-22
NCT02689284Combination Margetuximab and Pembrolizumab for Advanced, Metastatic HER2(+) Gastric or Gastroesophageal Junction CancerCOMPLETEDPHASE1, PHASE22016-012021-012021-01
NCT02628535Safety Study of MGD009 in B7-H3-expressing TumorsTERMINATEDPHASE12015-092019-11-252019-11-25
NCT02492711Margetuximab Plus Chemotherapy vs Trastuzumab Plus Chemotherapy in the Treatment of HER2+ Metastatic Breast CancerCOMPLETEDPHASE32015-08-242022-06-142021-08-11
NCT02475213Safety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory CancerCOMPLETEDPHASE12015-072021-08-182021-08-18
NCT02381314Safety Study of Enoblituzumab (MGA271) in Combination With Ipilimumab in Refractory CancerCOMPLETEDPHASE12015-03-262018-09-262017-11-09
NCT02376036Phase 1 Study of MGD010 in Healthy SubjectsCOMPLETEDPHASE12015-022017-022017-02
NCT02248805Phase 1 Study of MGD007 in Relapsed/Refractory Metastatic Colorectal CarcinomaCOMPLETEDPHASE12014-102018-07-022018-07-02
NCT02152956Flotetuzumab in Primary Induction Failure (PIF) or Early Relapse (ER) Acute Myeloid Leukemia (AML)TERMINATEDPHASE1, PHASE22014-06-092022-07-052022-07-05
NCT01918930Tissue Procurement Substudy for Participants in Study CP-MGA271-01TERMINATEDPHASE12013-072016-102016-10
NCT01828021Phase 2 Study of the Monoclonal Antibody MGAH22 (Margetuximab) in Patients With Relapsed or Refractory Advanced Breast CancerCOMPLETEDPHASE22013-032017-04-142016-12-07
NCT01391143Safety Study of MGA271 in Refractory CancerCOMPLETEDPHASE12011-072019-04-182019-04-18
NCT01189422Subcutaneous Administration of Teplizumab in Adults With Type 1 DiabetesTERMINATEDPHASE12010-082011-022011-02
NCT01148849Safety Study of MGAH22 in HER2-positive CarcinomasCOMPLETEDPHASE12010-072022-06-142022-06-14
NCT00954915Safety Study of the Monoclonal Antibody Teplizumab (MGA031) in Subjects With Moderate or More Severe PsoriasisTERMINATEDPHASE1, PHASE22009-122010-072010-07
NCT00920582Protege Encore Study- Clinical Trial of Teplizumab (MGA031) in Children and Adults With Recent-Onset Type 1 Diabetes MellitusTERMINATEDPHASE32009-092012-072012-04
NCT00927953Treatment of West Nile Virus With MGAWN1TERMINATEDPHASE22009-052011-052011-02
NCT00870818Protege Extension Trial - Long Term Follow Up Trial for Subjects Who Completed the Protege Study (CP-MGA031-01)TERMINATEDNA2009-022011-052011-02
NCT00625586Monoclonal Antibody RAV12 and Gemcitabine in Treating Patients With Metastatic Pancreatic CancerTERMINATEDPHASE22008-04-152009-03-182009-01-21
NCT00515385A Trial to Evaluate the Safety of a Single Intravenous Infusion of MGAWN1 in Healthy AdultsCOMPLETEDPHASE12007-082009-012008-12
NCT00385697The Protégé Study - Clinical Trial of MGA031 in Children and Adults With Recent-Onset Type 1 Diabetes MellitusCOMPLETEDPHASE2, PHASE32006-102011-082010-06
NCT00101972RAV12 in Treating Patients With Metastatic or Recurrent AdenocarcinomaCOMPLETEDPHASE12004-122008-052008-05