| NCT07179380 | Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) | NOT_YET_RECRUITING | PHASE3 | 2025-10-01 | 2028-12-30 | 2028-12-30 |
| NCT07102316 | A Study to Assess the Relative Bioavailability After a Single Inhalation Administration of Treprostinil Palmitil Inhalation Powder (TPIP) Formulation 2 (F2) to TPIP Formulation 3 (F3) in Healthy Participants | RECRUITING | PHASE1 | 2025-08-19 | 2025-11-09 | 2025-11-02 |
| NCT06817382 | A Study to Investigate the Safety and Biodistribution of a Single Intrathecal (IT) Injection of INS1201 in Ambulatory Males With Duchenne Muscular Dystrophy (DMD) | RECRUITING | PHASE1 | 2025-07-22 | 2028-03-31 | 2028-01-31 |
| NCT06685835 | A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa (HS) | RECRUITING | PHASE2 | 2024-12-16 | 2027-01-28 | 2026-05-22 |
| NCT06344728 | A Study to Assess the Relative Bioavailability of Brensocatib Pediatric Oral Solution to Oral Tablets in Healthy Participants | COMPLETED | PHASE1 | 2024-04-30 | 2024-05-24 | 2024-05-24 |
| NCT06178783 | A Study of the Palatability and Acceptability of Different Brensocatib Oral Liquid Formulations in Healthy Participants | COMPLETED | PHASE1 | 2023-12-27 | 2024-01-04 | 2024-01-04 |
| NCT06013241 | A Study of the Efficacy and Safety of Brensocatib in Participants With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) | ACTIVE_NOT_RECRUITING | PHASE2 | 2023-10-30 | 2025-09-25 | 2025-08-29 |
| NCT05965570 | A Study to Investigate Effect of Clarithromycin, a Strong CYP3A4 Inhibitor, on Brensocatib Pharmacokinetics in Healthy Participants | COMPLETED | PHASE1 | 2023-07-28 | 2023-09-22 | 2023-09-22 |
| NCT05649722 | An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) | ACTIVE_NOT_RECRUITING | PHASE2, PHASE3 | 2023-05-11 | 2026-03-14 | 2026-03-14 |
| NCT05826574 | A Study to Assess Pharmacokinetics (PK) of Brensocatib Alone and With Multiple Doses of Rifampin or Esomeprozole in Healthy Participants | COMPLETED | PHASE1 | 2023-05-10 | 2023-07-16 | 2023-07-16 |
| NCT05649748 | An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH) | ACTIVE_NOT_RECRUITING | PHASE2, PHASE3 | 2023-03-07 | 2026-12-31 | 2026-12-31 |
| NCT05176951 | A Study to Evaluate the Safety and Tolerability of Treprostinil Palmitil Inhalation Powder in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease | COMPLETED | PHASE2 | 2022-12-22 | 2024-03-14 | 2024-03-14 |
| NCT05517525 | A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Brensocatib in Participants With Normal Hepatic Function and Participants With Hepatic Impairment | COMPLETED | PHASE1 | 2022-10-04 | 2023-06-01 | 2023-06-01 |
| NCT05147805 | A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Treprostinil Palmitil Inhalation Powder in Participants With Pulmonary Arterial Hypertension | COMPLETED | PHASE2 | 2022-08-24 | 2025-03-27 | 2025-03-27 |
| NCT05355935 | A Study to Investigate the Effects of Brensocatib on QT Interval in Healthy Participants | COMPLETED | PHASE1 | 2022-04-27 | 2022-10-07 | 2022-10-07 |
| NCT04791514 | A Study of Treprostinil Palmitil Inhalation Powder (TPIP) In Pulmonary Arterial Hypertension (PAH) | TERMINATED | PHASE2 | 2022-03-29 | 2022-08-26 | 2022-08-26 |
| NCT05090904 | A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Brensocatib Tablets in Adults With Cystic Fibrosis | COMPLETED | PHASE2 | 2021-11-30 | 2022-11-01 | 2022-11-01 |
| NCT05652257 | A Study of the Absorption, Metabolism, and Excretion of [14C]-Brensocatib Following a Single Oral Administration in Healthy Male Participants | COMPLETED | PHASE1 | 2021-08-13 | 2021-09-14 | 2021-09-14 |
| NCT05673603 | A Study of Brensocatib Following a Single Oral Administration in Participants With or Without Renal Impairment | COMPLETED | PHASE1 | 2021-07-20 | 2023-02-14 | 2023-02-14 |
| NCT04677569 | Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex | ACTIVE_NOT_RECRUITING | PHASE3 | 2021-04-01 | 2026-01-15 | 2025-11-15 |
| NCT04677543 | Validation of Patient Reported Outcome Measures in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex | COMPLETED | PHASE3 | 2020-12-22 | 2023-05-09 | 2023-05-09 |
| NCT04594369 | A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis | COMPLETED | PHASE3 | 2020-12-01 | 2024-10-28 | 2024-10-28 |
| NCT06091579 | A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Treprostinil Palmitil Inhalation Powder (TPIP) in Healthy Participants | COMPLETED | PHASE1 | 2020-09-17 | 2021-01-12 | 2021-01-12 |
| NCT05927597 | A Study of the Safety, Pharmacokinetics, and Pharmacodynamics of INS1007 in Healthy Japanese and Caucasian Participants | COMPLETED | PHASE1 | 2019-01-09 | 2019-08-01 | 2019-08-01 |
| NCT03218917 | Assessment of INS1007 in Participants With Non-Cystic Fibrosis Bronchiectasis | COMPLETED | PHASE2 | 2017-10-31 | 2019-12-12 | 2019-12-12 |
| NCT02628600 | Open-label Safety Extension Study Assessing Safety and Tolerability of LAI in Patients Who Participated in Study INS-212 | COMPLETED | PHASE3 | 2016-02-05 | 2018-10-17 | 2018-10-17 |
| NCT06193031 | A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of C16TR for Inhalation With Tyvaso® Cohort in Healthy Participants | COMPLETED | PHASE1 | 2015-11-17 | 2015-12-18 | 2015-12-18 |
| NCT02344004 | Study to Evaluate Efficacy of LAI When Added to Multi-drug Regimen Compared to Multi-drug Regimen Alone | COMPLETED | PHASE3 | 2015-05-27 | 2019-04-03 | 2018-07-03 |
| NCT01316276 | Extension Study of Liposomal Amikacin for Inhalation in Cystic Fibrosis (CF) Patients With Chronic Pseudomonas Aeruginosa (Pa) Infection | COMPLETED | PHASE3 | 2012-10-05 | 2015-07-16 | 2015-07-16 |
| NCT01315236 | Liposomal Amikacin for Inhalation (LAI) for Nontuberculous Mycobacteria | COMPLETED | PHASE2 | 2012-04-19 | 2015-06-18 | 2014-08-18 |
| NCT01315678 | Study to Evaluate Arikayce™ in CF Patients With Chronic Pseudomonas Aeruginosa Infections | COMPLETED | PHASE3 | 2012-02-29 | 2013-09-18 | 2013-06 |
| NCT03905642 | Study of Dose Escalation of Liposomal Amikacin for Inhalation (ARIKAYCE™) - Extension Phase | COMPLETED | PHASE2 | 2009-01-08 | 2010-11-02 | 2010-11-02 |
| NCT00775138 | Safety and Tolerability Study of 2 Dose Level of Arikayce™ in Patients With Bronchiectasis and Chronic Infection Due to Pseudomonas Aeruginosa. | COMPLETED | PHASE2 | 2008-06-24 | 2009-05-11 | 2009-05-11 |
| NCT00558844 | Safety/Tolerability Study of Arikayce™ in Cystic Fibrosis Patients With Chronic Infection Due to Pseudomonas Aeruginosa | COMPLETED | PHASE1, PHASE2 | 2008-01 | 2009-06 | 2009-06 |
| NCT00577577 | Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-I/rhIGFBP-3) In Myotonic Dystrophy Type 1 | COMPLETED | PHASE2 | 2007-12 | 2008-12-29 | 2008-12-29 |
| NCT00777296 | Multidose Safety and Tolerability Study of Dose Escalation of Liposomal Amikacin for Inhalation (ARIKACE™) | COMPLETED | PHASE1, PHASE2 | 2007-02-22 | 2008-02-27 | 2008-02-27 |
| NCT00102531 | Inhalation SLIT Cisplatin (Liposomal) for the Treatment of Osteosarcoma Metastatic to the Lung | COMPLETED | PHASE1, PHASE2 | 2005-01-12 | 2008-03-17 | 2008-03 |
| NCT05999942 | A Study to Investigate Lung Deposition of Inhaled Amikacin-loaded Liposomes in Healthy Male Participants | COMPLETED | PHASE1 | 2004-06-02 | 2004-06-29 | 2004-06-29 |
| NCT06238856 | Single Dose Escalation Study of TR02 (Sustained Lipid Inhalation Technology [SLIT™] Amikacin) in Participants With Cystic Fibrosis (CF) Having Chronic Infections of Pseudomonas Aeruginosa | COMPLETED | PHASE1 | 2004-05-12 | 2005-02-08 | 2005-02-08 |
| NCT01315691 | Study to Evaluate Arikace™ in CF Patients With Chronic Infection Due to Pseudomonas Aeruginosa | WITHDRAWN | PHASE3 | | | |
| NCT00368173 | IGF-I/IGFBP-3 Therapy in Children and Adolescents With Growth Hormone Insenitivity Syndrome (GHIS) Such as Laron Syndrome | COMPLETED | PHASE2, PHASE3 | | | |
| NCT00351221 | Research Study Using Recombinant Human Insulin-Like Growth Factor-1/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 for Children With Noonan Syndrome | TERMINATED | PHASE2 | | | |