Clinical Trials - GRFS

NCT IDTitleStatusPhasesStart DateCompletion DatePrimary Completion Date
NCT04636268FIB Grifols Congenital Deficiency for On-demand Treatment and Surgical ProphylaxisWITHDRAWNPHASE32023-122025-032025-03
NCT05645107A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin LymphomaRECRUITINGPHASE32022-12-262026-062026-05
NCT04722887A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin DeficiencyACTIVE_NOT_RECRUITINGPHASE1, PHASE22021-08-132025-07-172025-07-17
NCT04847141A Study to Evaluate the Safety and Efficacy of C19-IG 20% in SARS-CoV-2 Infected Asymptomatic Ambulatory OutpatientsTERMINATEDPHASE32021-04-282021-12-272021-11-10
NCT04547140Study to Evaluate the Safety and Efficacy of Liquid Alpha1-Proteinase Inhibitor (Human) in Hospitalized Participants With Coronavirus Disease (COVID-19)TERMINATEDPHASE22021-01-292022-01-282021-12-13
NCT04566692A Study to Evaluate IGSC 20% Biweekly Dosing in Treatment-Experienced Participants and Loading/Maintenance Dosing in Treatment-Naïve Participants With Primary ImmunodeficiencyCOMPLETEDPHASE42020-11-242022-07-252022-07-18
NCT04480424Study to Evaluate the Safety and Efficacy of High Dose Intravenous Immune Globulin (IVIG) Plus Standard Medical Treatment (SMT) Versus SMT Alone in Participants in Intensive Care Unit (ICU) With Coronavirus Disease (COVID-19)COMPLETEDPHASE22020-09-172021-10-252021-08-25
NCT04561115A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Immune Globulin (Human) 10% (Gamunex-C) PEG Process (IVIG-PEG) Compared to Gamunex-C in Participants With Primary Humoral ImmunodeficiencyCOMPLETEDPHASE32020-09-022022-03-282022-03-28
NCT04495101Study to Evaluate the Safety and Efficacy of Prolastin in Hospitalized Subjects With COVID-19COMPLETEDPHASE22020-07-292021-06-102021-04-26
NCT04432324Study to Evaluate the Safety and Efficacy of High Dose IVIG in Hospitalized Participants With Coronavirus Disease (COVID-19)COMPLETEDPHASE22020-06-022021-03-032021-03-03
NCT04547127A Study to Evaluate Safety and Efficacy of Convalescent Methylene Blue Treated (MBT) Plasma From Donors Recovered From Coronavirus Disease 2019 (COVID-19)COMPLETEDPHASE22020-04-292021-02-042021-02-04
NCT03814798Study Evaluating IGSC 20% Flexible Dosing in Treatment-Experienced and Treatment-Naive Subjects With Primary ImmunodeficiencyWITHDRAWNPHASE32019-122020-092020-09
NCT03702920Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5%TERMINATEDPHASE32019-02-212025-04-142025-04-14
NCT03461406A Study of Safety and Efficacy of Fibrin Sealant Grifols as an Adjunct to Haemostasis During Surgery in Paediatric ParticipantsCOMPLETEDPHASE32019-01-182022-05-202022-04-15
NCT03451292Effects of Long-Term Administration of Human Albumin in Participants With Decompensated Cirrhosis and AscitesCOMPLETEDPHASE32018-07-242024-05-212024-05-21
NCT03095287Alphanate in Immune Tolerance Induction TherapyTERMINATEDPHASE22018-01-032020-09-182020-09-18
NCT03351933Anti-Hepatitis A Virus, Pharmacokinetics, and Safety of Immune Globulin (Human)COMPLETEDPHASE42017-10-312018-07-192018-04-27
NCT02872142Efficacy and Safety of Plasma Exchange With Albutein® 5% in Participants With Amyotrophic Lateral SclerosisCOMPLETEDPHASE22016-08-292019-08-152019-08-15
NCT02870348Long-term Safety of Alpha1-Proteinase Inhibitor (Human) in Japanese Subjects With Alpha1 Antitrypsin Deficiency (GTI1401-OLE)COMPLETEDPHASE1, PHASE22016-07-292021-02-162021-02-16
NCT02870309Safety and Pharmacokinetics of Alpha-1 MP (Alpha1-proteinase Inhibitor (Human), Modified Process) in Participants With Alpha1-Antitrypsin DeficiencyCOMPLETEDPHASE1, PHASE22016-07-292017-03-152017-03-15
NCT02281500Pharmacokinetics, Efficacy, and Safety of Human Plasma-Derived Fibrinogen (FIB Grifols) in Participants With Congenital AfibrinogenemiaCOMPLETEDPHASE1, PHASE22016-07-222019-11-112019-11-11
NCT02796937Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin DeficiencyENROLLING_BY_INVITATIONPHASE32016-072029-022028-09
NCT02806986Efficacy, Pharmacokinetics, Safety, and Tolerability of IGSC 20% in Subjects With Primary ImmunodeficiencyCOMPLETEDPHASE32016-062019-05-152019-05-15
NCT02604810Safety and Pharmacokinetics of IGSC 20% in Subjects With Primary ImmunodeficiencyCOMPLETEDPHASE32016-012017-122017-09
NCT02473952A Study to Evaluate the Efficacy and Safety of IGIV-C in Symptomatic Subjects With Generalized Myasthenia GravisCOMPLETEDPHASE22015-082018-012018-01
NCT02473965Efficacy and Safety of IGIV-C in Corticosteroid Dependent Patients With Generalized Myasthenia GravisCOMPLETEDPHASE22015-062019-022019-02
NCT02413580A Study to Assess the Efficacy and Safety of IGIV-C in Patients With Myasthenia Gravis ExacerbationsCOMPLETEDPHASE32015-032018-042018-04
NCT02282527A Study to Assess Safety and PK of Liquid Alpha₁-Proteinase Inhibitor (Human) in Treating Alpha₁-Antitrypsin DeficiencyCOMPLETEDPHASE2, PHASE32014-102016-012016-01
NCT02176863Study of the Efficacy and Safety of Immune Globulin Intravenous (Human) Flebogamma® 5% DIF in Patients With Post-polio SyndromeTERMINATEDPHASE2, PHASE32014-09-232022-11-242022-11-24
NCT02037555Safety and Efficacy of Preoperative Antithrombin Supplementation in Patients Undergoing High-Risk Cardiopulmonary BypassCOMPLETEDPHASE22014-06-262018-01-252018-01-25
NCT02093221Study of Human Plasma-Derived Alpha1-Proteinase Inhibitor in Subjects With New-Onset Type 1 Diabetes MellitusTERMINATEDPHASE22014-032017-062017-01
NCT02139657An Open-label, Single-Arm Study to Evaluate the Safety and Rabies Virus Antibody Titers of Intramuscularly Administered Rabies Immune Globulin (Human)COMPLETEDPHASE12014-032014-052014-05
NCT02472665Efficacy and Safety of Fanhdi®, a High-purity Von Willebrand Containing FVIII Concentrate, in Pediatric Patients With Von Willebrand DiseaseRECRUITINGPHASE42013-122026-122025-04
NCT01983241Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD)ACTIVE_NOT_RECRUITINGPHASE32013-112027-012026-08
NCT01684410Safety and Tolerability Trial of Inhaled Alpha1-Proteinase Inhibitor (Human), Hydrophobic Chromatography Process (Alpha-1 HC) in Subjects With Cystic FibrosisCOMPLETEDPHASE22012-082013-102013-10
NCT01465958Pharmacokinetics, Safety, and Tolerability of Subcutaneous GAMUNEX-C in Pediatric Subjects With Primary ImmunodeficiencyCOMPLETEDPHASE42011-112013-102013-10
NCT01201720Effects on Plasma Exchange on Functional Capacity of Serum Albumin, Circulatory Dysfunction, Renal and Cerebral Function in Cirrhotic Patients With "Acute-on-chronic Liver Failure"COMPLETEDNA2011-032013-022013-01
NCT01222117A Study of Intra-thrombus Plasmin (Human) In Acute Peripheral Arterial OcclusionCOMPLETEDPHASE22010-122016-012015-12
NCT01213043Safety and Pharmacokinetics of Alpha-1 Proteinase Inhibitor in Subjects With Alpha1-Antitrypsin DeficiencyCOMPLETEDPHASE22010-112012-012012-01
NCT01014975A Safety and Dose Finding Study of Plasmin (Human) Administered Into the Middle Cerebral Artery of Stroke PatientsCOMPLETEDPHASE1, PHASE22009-112014-022013-11
NCT00968695Effects of Long Term Albumin 20% Administration in Patients With Cirrhosis and Ascites.COMPLETEDPHASE42009-072014-042014-04
NCT00418483A Dose Escalation and Safety Study of Plasmin (Human) In Acute Lower Extremity Native Artery or Bypass Graft OcclusionCOMPLETEDPHASE12007-032010-042010-04
NCT00437671Tetanus Immunization in Subjects With No Immunization History or With Tetanus Antibody Levels Below Protective LevelsTERMINATEDPHASE42007-032007-092007-09
NCT00389324A Trial of the Pharmacokinetics, Safety, and Tolerability of Subcutaneous Gamunex® in Primary ImmunodeficiencyCOMPLETEDPHASE22006-112008-082008-08
NCT00301366The Safety and Tolerability of Alpha-1 Modified Process (MP) In Subjects With Alpha-1-antitrypsin (AAT) DeficiencyCOMPLETEDPHASE32006-062007-032007-03
NCT00295061Comparison of Pharmacokinetic, Safety, Tolerability of Alpha-1 MP and Prolastin In Alpha1-antitrypsin Deficient AdultsCOMPLETEDPHASE32006-052007-022007-02
NCT00220740Immune Globulin Intravenous (IGIV) For Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)COMPLETEDPHASE32004-042006-062006-06
NCT00220805Use of Immune Globulin Intravenous (Human) To Treat Age-Related Macular DegenerationCOMPLETEDPHASE22004-012005-052005-05
NCT00486837Deposition of Inhaled Prolastin in Cystic Fibrosis PatientsCOMPLETEDPHASE22003-122004-062004-06
NCT00263887Alpha-1-Antitrypsin (AAT) To Treat Emphysema In AAT-Deficient Patients (EXACTLE)COMPLETEDPHASE22003-122007-012007-01
NCT00220727Rapid Infusion Of Immune Globulin Intravenous (IGIV) In Patients With ITPCOMPLETEDPHASE22003-072003-102003-10
NCT00220779Immune Globulin Intravenous (IGIV) To Treat Relapsing, Remitting Multiple SclerosisCOMPLETEDPHASE22002-122005-022005-02
NCT00220766Rapid Infusion of Immune Globulin Intravenous (Human) In Primary Immunodeficiency PatientsCOMPLETEDPHASE32002-082004-032002-08