Clinical Trials - GMAB

NCT IDTitleStatusPhasesStart DateCompletion DatePrimary Completion Date
NCT07166094Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial CancerNOT_YET_RECRUITINGPHASE32025-10-152029-022028-11
NCT06984328Study of the Effectiveness and Safety of Acasunlimab Alone and With Pembrolizumab to Treat Advanced Melanoma of the Skin That Has Returned After Treatment With an Approved Checkpoint Inhibitor Therapy (ABBIL1TY MELANOMA-07)RECRUITINGPHASE22025-07-252029-07-152027-07-15
NCT06619236Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian CancerRECRUITINGPHASE32025-02-072028-04-052027-05-02
NCT06771921A First-in-Human Trial of Safety and Efficacy of GEN1078 in Participants With Solid TumorsTERMINATEDPHASE1, PHASE22025-01-292025-06-112025-06-11
NCT06635824Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)RECRUITINGPHASE32024-11-252029-10-312027-01-31
NCT06685068A Phase 1/2 Study of GEN1286 in Patients With Advanced Solid TumorsRECRUITINGPHASE1, PHASE22024-11-132028-06-292028-05-29
NCT06573294Trial to Assess the Safety and Antitumor Activity of GEN1057 in Malignant Solid TumorsRECRUITINGPHASE12024-08-282026-01-312025-09-30
NCT06508658A Study of Subcutaneously Injected Epcoritamab Plus Oral Lenalidomide Tablets Compared to Intravenously (IV) Infused Rituximab Plus IV Infused Gemcitabine and IV Infused Oxaliplatin in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell LymphomaRECRUITINGPHASE32024-08-132028-012028-01
NCT06391775Trial to Assess the Safety and Preliminary Efficacy of GEN1055 on Malignant Solid Tumors as Monotherapy and as Combination TherapyACTIVE_NOT_RECRUITINGPHASE1, PHASE22024-05-142028-052028-05
NCT06191744Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular LymphomaRECRUITINGPHASE32024-02-052037-112037-11
NCT06171789PRO1107 in Patients With Advanced Solid TumorsTERMINATEDPHASE1, PHASE22024-01-292025-08-182025-08-18
NCT06057038A Safety Trial of GEN1042 in Japanese Subjects With Malignant Solid TumorsACTIVE_NOT_RECRUITINGPHASE12023-11-242026-12-262026-03-26
NCT06046274GEN1046 in Combination With Anticancer Agents for the Treatment of Advanced Endometrial CancerWITHDRAWNPHASE22023-10-012028-06-012028-04-01
NCT06018129A First-in-human Trial of GEN3017 in Hodgkin Lymphoma and Non-Hodgkin LymphomaTERMINATEDPHASE1, PHASE22023-09-212025-02-052025-02-05
NCT05721222Trial of PRO1160 (GEN1160) in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) (PRO1160-001)RECRUITINGPHASE1, PHASE22023-03-152026-12-312026-09-15
NCT05491317A Safety and Antitumor Activity Trial of Immunoradiotherapy Combinations as a Treatment Option for Subjects With Metastatic Solid TumorsACTIVE_NOT_RECRUITINGPHASE1, PHASE22023-03-082025-112025-11
NCT05660967Subcutaneous Epcoritamab With or Without Lenalidomide as First Line Therapy for Diffuse Large B-Cell LymphomaACTIVE_NOT_RECRUITINGPHASE22023-03-062027-07-312026-01-30
NCT05578976A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)ACTIVE_NOT_RECRUITINGPHASE32023-02-082029-122027-06
NCT05579366Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)RECRUITINGPHASE1, PHASE22022-12-072027-092027-06
NCT05586321Study of Safety and Antitumor Activity of GEN1056 in Participants With Advanced Solid TumorsACTIVE_NOT_RECRUITINGPHASE12022-10-242025-10-212025-10-21
NCT05435339A Study to Evaluate Safety, Tolerability, and Preliminary Effect of the GEN1053 Antibody on Malignant Solid Tumors as MonotherapyTERMINATEDPHASE1, PHASE22022-10-042024-05-242024-05-24
NCT05206357Study of the Adverse Events and Change in Disease State of Pediatric Participants (and Young Adults Between the Ages of 18-25) With Relapsed/Refractory Aggressive Mature B-cell Neoplasms Receiving Subcutaneous (SC) Injections of EpcoritamabACTIVE_NOT_RECRUITINGPHASE12022-10-042028-112028-11
NCT05409066Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular LymphomaACTIVE_NOT_RECRUITINGPHASE32022-09-202029-122029-12
NCT05451810A Study to Evaluate Adverse Events of Subcutaneous (SC) Epcoritamab Administered in the Outpatient Setting in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma and Classic Follicular LymphomaACTIVE_NOT_RECRUITINGPHASE22022-08-172027-032027-03
NCT05283720A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin LymphomaRECRUITINGPHASE22022-06-142032-112032-11
NCT05201248A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab As Monotherapy or Combined With Standard of Care Therapies in Adult Participants in China With B-Cell Non-Hodgkin LymphomaACTIVE_NOT_RECRUITINGPHASE1, PHASE22022-03-102025-042025-04
NCT05180474GEN1047 for Solid Tumors - First in Human (FIH) TrialACTIVE_NOT_RECRUITINGPHASE1, PHASE22021-12-132026-03-262026-03-26
NCT05117242Safety and Efficacy Study of GEN1046 as a Single Agent or in Combination With Pembrolizumab for Treatment of Recurrent (Non-small Cell) Lung CancerACTIVE_NOT_RECRUITINGPHASE22021-10-272027-032024-12-02
NCT04937153GEN1046 Safety and PK in Subjects With Advanced Solid MalignanciesCOMPLETEDPHASE12021-06-152024-10-012024-10-01
NCT04824794GEN3014 Trial in Relapsed or Refractory Hematologic MalignanciesTERMINATEDPHASE1, PHASE22021-03-092025-07-312025-06-30
NCT04628494A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)ACTIVE_NOT_RECRUITINGPHASE32021-01-132028-042025-12
NCT04623541Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's SyndromeRECRUITINGPHASE1, PHASE22020-11-252029-082029-06
NCT04663347Safety and Efficacy Trial of Epcoritamab Combinations in Subjects With B-cell Non-Hodgkin Lymphoma (B-NHL)ACTIVE_NOT_RECRUITINGPHASE1, PHASE22020-11-032028-09-302028-09-30
NCT04542824Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (R/R B-NHL)ACTIVE_NOT_RECRUITINGPHASE1, PHASE22020-08-202027-092027-09
NCT04424641A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid TumorsTERMINATEDPHASE1, PHASE22020-07-152021-10-292021-10-29
NCT04358458First-in-Human (FIH) Trial of GEN3009 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin LymphomasTERMINATEDPHASE1, PHASE22020-03-132023-07-282022-11-21
NCT04083599GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid TumorsACTIVE_NOT_RECRUITINGPHASE1, PHASE22019-09-172026-112025-12
NCT03917381GEN1046 Safety Trial in Patients With Malignant Solid TumorsACTIVE_NOT_RECRUITINGPHASE1, PHASE22019-05-142026-022025-04-01
NCT03913741A Trial of Tisotumab Vedotin in Japanese Subjects With Advanced Solid MalignanciesCOMPLETEDPHASE1, PHASE22019-02-272021-10-302020-08-14
NCT03625037First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell LymphomaACTIVE_NOT_RECRUITINGPHASE1, PHASE22018-06-262029-012029-01
NCT03576131GEN1029 (HexaBody®-DR5/DR5) Safety Trial in Patients With Malignant Solid TumorsTERMINATEDPHASE1, PHASE22018-04-302021-10-122021-10-12
NCT02988817Enapotamab Vedotin (HuMax-AXL-ADC) Safety Study in Patients With Solid TumorsCOMPLETEDPHASE1, PHASE22016-11-232021-11-122021-11-12
NCT01054625Zalutumumab Pharmacokinetics (PK) in Squamous Cell Carcinoma of the Head and Neck (SCCHN)COMPLETEDPHASE1, PHASE22010-032011-102011-07
NCT00707655Zalutumumab in Combination With Radiotherapy in Head and Neck Cancer Patients Ineligible for Platinum Based ChemotherapyTERMINATEDPHASE1, PHASE22008-092010-102010-10
NCT00677924Zalutumumab With or Without Irinotecan Chemotherapy in Cetuximab-Refractory Colorectal CancerTERMINATEDPHASE1, PHASE22008-042009-042009-04
NCT00542308Zalutumumab in Non-curable Patients With SCCHNCOMPLETEDPHASE22008-012011-082011-08
NCT00460551Zalutumumab in Combination With Chemo-Radiation in a Certain Type of Lung CancerTERMINATEDPHASE22007-042008-102008-10
NCT00401401Zalutumumab in Combination With Chemotherapy and Radiotherapy in Head and Neck CancerTERMINATEDPHASE1, PHASE22006-122010-102010-10
NCT00382031Zalutumumab in Patients With Non-curable Head and Neck CancerCOMPLETEDPHASE32006-112011-082009-12
NCT00093041Zalutumumab in Head and Neck CancerCOMPLETEDPHASE1, PHASE22003-12-012005-01-122005-01-12
NCT00071084Clinical Trial of HuMax-CD4, a New Drug to Treat Advanced Stage T-Cell Lymphoma in the Skin.COMPLETEDPHASE22003-05-272004-06-292004-06-29
NCT00071071Clinical Trial of HuMax-CD4, a New Drug to Treat Early Stage T-Cell Lymphoma in the Skin.COMPLETEDPHASE22003-04-302004-05-052004-05-05
NCT00042406Trial With HuMax-CD4 in Participants With Rheumatoid Arthritis (RA) Failing Treatment With Methotrexate (MTX) and a TNF-alpha BlockerTERMINATEDPHASE2, PHASE32002-03-042003-03-312003-03-31
NCT01449357Zalutumumab in Non-Small Cell Lung Cancer (NSCLC) Patients Refractory to Tyrosine Kinase InhibitorsWITHDRAWNPHASE2