Clinical Trials - GERN

NCT IDTitleStatusPhasesStart DateCompletion DatePrimary Completion Date
NCT05371964A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Participants With MyelofibrosisRECRUITINGPHASE12022-05-042028-082027-02
NCT04576156A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor TreatmentRECRUITINGPHASE32021-04-122028-06-302028-06-30
NCT02426086Study to Evaluate Activity of 2 Dose Levels of Imetelstat in Participants With Intermediate-2 or High-Risk Myelofibrosis (MF) Previously Treated With Janus Kinase (JAK) InhibitorCOMPLETEDPHASE22015-08-282020-02-072018-04-26
NCT01731951Imetelstat Sodium in Treating Participants With Primary or Secondary MyelofibrosisCOMPLETEDPHASE22012-10-292018-05-242018-05-24
NCT01243073Open Label Study to Evaluate the Activity of Imetelstat in Patients With Essential Thrombocythemia or Polycythemia VeraCOMPLETEDPHASE22010-122015-042013-10
NCT01242930Open Label Study With Imetelstat to Determine Effect of Imetelstat in Patients w/ Previously Treated Multiple MyelomaCOMPLETEDPHASE22010-112014-112014-11
NCT01256762Imetelstat in Combination With Paclitaxel (With or Without Bevacizumab) in Patients With Locally Recurrent or Metastatic Breast CancerCOMPLETEDPHASE22010-112012-122012-10
NCT01137968Imetelstat as Maintenance Therapy After Initial Induction Chemotherapy in Non-small Cell Lung Cancer (NSCLC)COMPLETEDPHASE22010-052013-092013-09
NCT00732056A Study of GRN163L With Paclitaxel and Bevacizumab to Treat Patients With Locally Recurrent Or Metastatic Breast CancerCOMPLETEDPHASE12008-072012-032011-09
NCT00718601Safety and Dose Study of GRN163L and Velcade to Treat Patients With Refractory or Relapsed MyelomaCOMPLETEDPHASE12008-072011-102011-10
NCT00594126Safety and Dose Study of GRN163L Administered to Treat Patients With Refractory or Relapsed Multiple MyelomaCOMPLETEDPHASE12007-112011-072011-07
NCT00510445Study of GRN163L With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Non Small Cell Lung CancerCOMPLETEDPHASE12007-072011-042011-04
NCT00310895Safety and Dose Study of GRN163L Administered to Patients With Refractory or Relapsed Solid Tumor MalignanciesCOMPLETEDPHASE12006-032013-032013-03
NCT00124189Safety and Dose Study of GRN163L to Treat Patients With Chronic Lymphoproliferative Disease(CLD)COMPLETEDPHASE12005-072013-032013-03