Clinical Trials - FGEN

NCT IDTitleStatusPhasesStart DateCompletion DatePrimary Completion Date
NCT06842498A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)NOT_YET_RECRUITINGPHASE22025-09-152028-03-312028-03-31
NCT04621331Investigating the Efficacy, Safety and PK of Roxadustat (FG-4592) for Treatment of Anemia in Pediatric Patients With CKDWITHDRAWNPHASE32022-05-232022-05-232022-05-23
NCT05301517A Study to Evaluate the Efficacy and Safety of Roxadustat for the Treatment of Anemia in Participants Receiving Chemotherapy Treatment for Non-Myeloid MalignanciesCOMPLETEDPHASE32022-03-162023-04-212023-04-03
NCT04632940Phase 3 Trial of Pamrevlumab or Placebo in Combination With Systemic Corticosteroids in Participants With Ambulatory DMDTERMINATEDPHASE32021-03-032023-12-142023-06-12
NCT04419558Zephyrus II: Efficacy and Safety Study of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)TERMINATEDPHASE32020-09-302023-09-042023-09-04
NCT04371666Phase 3 Trial of Pamrevlumab or Placebo With Systemic Corticosteroids in Participants With Non-ambulatory Duchenne Muscular Dystrophy (DMD)TERMINATEDPHASE32020-08-102023-08-172023-02-13
NCT04484857Study of Roxadustat Conversion in Participants Receiving Stable ESA or as Initial Anemia Treatment in Hemodialysis ParticipantsCOMPLETEDPHASE32020-07-222021-09-172021-07-09
NCT04432298Study of the Efficacy and Safety of Intravenous Pamrevlumab, in Hospitalized Participants With Acute COVID-19 DiseaseTERMINATEDPHASE22020-06-202021-03-222021-03-22
NCT04410198Study of Roxadustat Conversion in Participants Receiving Stable Erythropoiesis-Stimulating Agent (ESA) or as Initial Anemia Treatment in Chronic Dialysis ParticipantsCOMPLETEDPHASE32020-05-262021-10-112021-06-30
NCT04076943Evaluation of Efficacy and Safety of Roxadustat for the Treatment of Chemotherapy Induced AnemiaCOMPLETEDPHASE22019-08-202021-04-232021-03-26
NCT03955146Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)TERMINATEDPHASE32019-06-182023-08-282023-03-20
NCT04059913Evaluate the Efficacy and Safety of Multiple Roxadustat Dosing Regimens for the Treatment of Anemia in Dialysis Participants With Chronic Kidney DiseaseCOMPLETEDPHASE42019-06-112021-12-172021-11-19
NCT03941093Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Participants With Locally Advanced, Unresectable Pancreatic CancerCOMPLETEDPHASE32019-05-102024-06-112024-06-11
NCT03303066Efficacy and Safety of FG-4592 for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome (MDS)COMPLETEDPHASE2, PHASE32018-06-062023-02-082023-01-11
NCT03263091Efficacy and Safety of Roxadustat for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome With Low Red Blood Cell Transfusion BurdenTERMINATEDPHASE32018-01-292023-06-202023-03-09
NCT02606136Trial of Pamrevlumab (FG-3019), in Non-Ambulatory Participants With Duchenne Muscular Dystrophy (DMD)TERMINATEDPHASE22016-01-042023-08-092020-05-07
NCT02652819FG-4592 for Treatment of Anemia in Subjects With Chronic Kidney Disease Not on DialysisCOMPLETEDPHASE32015-122017-06-132017-01-24
NCT02652806FG-4592 for Treatment of Anemia in Subjects With Chronic Kidney DiseaseCOMPLETEDPHASE32015-122017-06-142017-01-24
NCT02273726Study to Evaluate the Efficacy and Safety of Roxadustat in the Treatment of Anemia in Participants With ESRD on Stable DialysisCOMPLETEDPHASE32015-01-152018-09-192018-09-19
NCT02210559A Study of Gemcitabine Plus Nab-paclitaxel With or Without FG-3019 in Participants With Locally Advanced, Unresectable Pancreatic CancerCOMPLETEDPHASE1, PHASE22014-07-312021-12-152021-12-15
NCT02052310Safety and Efficacy Study of Roxadustat (FG-4592) for the Treatment of Anemia in End-Stage Renal Disease (ESRD) Newly Initiated Dialysis ParticipantsCOMPLETEDPHASE32014-02-112018-09-212018-09-21
NCT01890265Evaluate the Safety and Efficacy of FG-3019 (Pamrevlumab) in Participants With Idiopathic Pulmonary Fibrosis (IPF)COMPLETEDPHASE22013-07-302017-11-162017-11-16
NCT01750190A Study of Roxadustat for the Treatment of Anemia in Participants With Chronic Kidney Disease and Not Receiving DialysisCOMPLETEDPHASE32012-11-052018-09-242018-09-24
NCT01630889Open-Label Extension Study for the Long-Term Efficacy and Safety of Roxadustat in Participants With Dialysis and Non-Dialysis Chronic Kidney DiseaseCOMPLETEDPHASE22012-05-182019-12-122019-12-12
NCT01599507Study of FG-4592 in Subjects With Chronic Kidney Disease in ChinaCOMPLETEDPHASE22011-122013-012013-01
NCT01596855Study of FG-4592 in Subjects With End-Stage Renal Disease Receiving Maintenance Hemodialysis in ChinaCOMPLETEDPHASE22011-092013-012013-01
NCT01414075Study of Roxadustat (FG-4592) to Correct Anemia in Newly Initiated Dialysis Participants Not on Erythropoiesis-Stimulating Agent TreatmentCOMPLETEDPHASE22011-07-212013-01-102013-01-10
NCT01262001Safety, Tolerability, and Efficacy Study of Idiopathic Pulmonary FibrosisCOMPLETEDPHASE22011-032017-06-212014-06-26
NCT01244763Study of Roxadustat in Non-Dialysis Chronic Kidney Disease Participants With AnemiaCOMPLETEDPHASE22010-10-292012-06-132012-06-13
NCT01217632A Study of FG-3019 in Subjects With Liver Fibrosis Due to Chronic Hepatitis B InfectionTERMINATEDPHASE22010-082015-062015-06
NCT01147666Study of Roxadustat (FG-4592) in Participants With End-Stage Renal Disease Receiving Maintenance HemodialysisCOMPLETEDPHASE22010-05-172012-10-152012-10-15
NCT01376063Study to Investigate the Interaction Between FG-4592 and Rosiglitazone in Healthy Adult SubjectsCOMPLETEDPHASE12010-032010-062010-05
NCT00913393Study of FibroGen (FG)-3019 in Subjects With Type 2 Diabetes Mellitus and Kidney Disease on ACEi and/or ARB TherapyTERMINATEDPHASE22009-022010-062010-06
NCT01181245A Phase 1 Study of Safety and Bioactivity With FG-3019 in Combination With Gemcitabine and Erlotinib for Subjects With Locally Advanced or Metastatic Pancreatic CancerCOMPLETEDPHASE12008-122014-062014-05
NCT00782561Safety and Pharmacokinetics of FG-3019 in Adolescents and Adults With Focal Segmental Glomerulosclerosis (FSGS)TERMINATEDPHASE12008-042009-06-182009-06-18
NCT00754143Phase 1 Study of FG-3019 in Subjects With Type 1 or Type 2 Diabetes Mellitus and Diabetic NephropathyCOMPLETEDPHASE12008-032009-122009-12
NCT00761657Phase 2 Study of Roxadustat in Participants With Anemia and Chronic Kidney Disease Not Requiring DialysisCOMPLETEDPHASE22006-11-012010-06-212010-06-21
NCT00456053A Randomized Study of the Safety and Efficacy of FG-2216 in Subjects With Renal Anemia Not Requiring Dialysis and Not Receiving Recombinant Human ErythropoietinCOMPLETEDPHASE22005-122007-07
NCT00102297Study of the Safety of FG-3019 in Incipient Nephropathy Due to Type 1 or Type 2 Diabetes MellitusCOMPLETEDPHASE12005-012007-06
NCT00074698Safety and Tolerability Study of FG-3019 in Participants With Idiopathic Pulmonary FibrosisCOMPLETEDPHASE12003-12-082004-05