Clinical Trials - ESPR

NCT IDTitleStatusPhasesStart DateCompletion DatePrimary Completion Date
NCT06021951Milk-Only Lactation Study to Evaluate the Concentration of Bempedoic Acid and Bempedoic Acid/Ezetimibe Fixed Combination Drug Product (FCDP) in the Breast Milk of Healthy Lactating WomenCOMPLETEDPHASE42023-08-042024-03-222024-02-21
NCT05694260A Clinical Study in Children With Heterozygous Familial Hypercholesterolemia (HeFH) Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1)COMPLETEDPHASE22023-01-122025-06-042025-06-04
NCT03531905Bempedoic Acid + Ezetimibe Fixed-Dose Combination (FDC) Study in Patients With Type 2 Diabetes and Elevated LDL-CCOMPLETEDPHASE22018-05-092019-06-182019-06-18
NCT03337308A Study Evaluating the Safety and Efficacy of Bempedoic Acid Plus Ezetimibe Fixed-Dose Combination Compared to Bempedoic Acid, Ezetimibe, and Placebo in Patients Treated With Maximally Tolerated Statin TherapyCOMPLETEDPHASE32017-10-232018-07-182018-06-18
NCT03193047Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg When Added to PCSK9 Inhibitor TherapyCOMPLETEDPHASE22017-04-072018-02-192018-01-29
NCT03067441Assessment of the Long-Term Safety and Efficacy of Bempedoic Acid (CLEAR Harmony OLE)COMPLETEDPHASE32017-02-032019-11-052019-11-05
NCT03051100Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg, Ezetimibe 10mg, and Atorvastatin 20 mg Triplet Therapy in Patients With Elevated LDL-CCOMPLETEDPHASE22017-01-192017-07-052017-06-01
NCT02993406Evaluation of Major Cardiovascular Events in Participants With, or at High Risk for, Cardiovascular Disease Who Are Statin Intolerant Treated With Bempedoic Acid (ETC-1002) or PlaceboCOMPLETEDPHASE32016-12-222022-11-072022-11-07
NCT03001076Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility)COMPLETEDPHASE32016-11-292018-02-122018-01-11
NCT02991118Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular RiskCOMPLETEDPHASE32016-11-182018-08-222018-08-22
NCT02988115Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia and Statin IntolerantCOMPLETEDPHASE32016-11-162018-03-162018-03-16
NCT02666664Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony)COMPLETEDPHASE32016-01-212018-03-282018-02-21
NCT02659397A Study Of Pharmacokinetics, Pharmacodynamics And Safety Of Adding ETC-1002 To Atorvastatin 80 mgCOMPLETEDPHASE22015-122016-072016-07
NCT02178098Evaluation of ETC-1002 in Participants With Hypercholesterolemia and HypertensionCOMPLETEDPHASE22014-06-162015-05-222015-05-22
NCT02072161Evaluation of ETC-1002 vs Placebo in Patients Receiving Ongoing Statin TherapyCOMPLETEDPHASE22014-032015-012015-01
NCT02044627Single Radiolabeled Dose Study to Investigate the Absorption, Metabolism and Excretion of [14C]-ETC-1002COMPLETEDPHASE12013-122014-012014-01
NCT01941836Evaluation of ETC-1002, Ezetimibe, and the Combination in Hypercholesterolemic PatientsCOMPLETEDPHASE22013-092014-112014-10
NCT01779453A Study of the Safety, Pharmacokinetic Drug Interaction and Efficacy of ETC-1002 and Atorvastatin in Subjects With HypercholesterolemiaCOMPLETEDPHASE22012-122013-082013-08
NCT01751984A Study of the Efficacy and Safety of ETC-1002 in Participants With Statin IntoleranceCOMPLETEDPHASE22012-10-042013-05-012013-05-01
NCT01607294A Single Center Study to Evaluate the Efficacy and Safety of ETC 1002 in Subjects With Type 2 DiabetesCOMPLETEDPHASE22012-042012-102012-10
NCT01485146A Multiple Ascending Dose Study of ETC-1002 in Healthy SubjectsCOMPLETEDPHASE12011-10-252012-01-252012-01-25
NCT01262638A Study to Assess the Efficacy and Safety of ETC-1002 in Subjects With Elevated Blood Cholesterol and Either Normal or Elevated TriglyceridesCOMPLETEDPHASE22010-122011-08-232011-08-23
NCT01105598A Multiple Ascending Dose Study of ETC-1002 in Subjects With Mild DyslipidemiaCOMPLETEDPHASE12010-04-202010-10-022010-10-02