Clinical Trials - CYCN

NCT IDTitleStatusPhasesStart DateCompletion DatePrimary Completion Date
NCT03892499A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator, Olinciguat (IW-1701), in Healthy VolunteersCOMPLETEDPHASE12019-05-032019-07-032019-06-23
NCT03818295A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Praliciguat in Healthy Male VolunteersCOMPLETEDPHASE12019-03-012019-04-242019-04-24
NCT03795519A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Olinciguat in Healthy Male VolunteersCOMPLETEDPHASE12019-01-172019-02-272019-02-27
NCT03499106A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy VolunteersCOMPLETEDPHASE12018-04-122018-07-062018-07-06
NCT03285178A Study of the Effect of IW-1701 (Olinciguat), a Stimulator of Soluble Guanylate Cyclase (sGC), on Patients With Sickle Cell Disease (SCD)COMPLETEDPHASE22017-12-222020-07-222020-07-22
NCT02931565Study of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Patients With Type I or II AchalasiaTERMINATEDPHASE22017-04-062018-05-012018-05-01
NCT03091920Trial of IW-1973, A Stimulator of Soluble Guanylate Cyclase (sGC) in Patients With Stable Type 2 Diabetes and HypertensionCOMPLETEDPHASE22017-02-282017-08-032017-08-03
NCT02906579A Phase 2 Trial of IW-1973, A Stimulator of Soluble Guanylate Cyclase (sGC), in Patients With Stable Type 2 Diabetes and HypertensionCOMPLETEDPHASE22016-092017-03-172017-03-17
NCT02792998A Trial of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Healthy SubjectsCOMPLETEDPHASE12016-052016-112016-11
NCT02616861Trial of IW-1973 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy VolunteersCOMPLETEDPHASE12015-112016-062016-05
NCT02572349Trial of IW-1701 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy VolunteersCOMPLETEDPHASE12015-102015-122015-12