Clinical Trials - CLDX

NCT IDTitleStatusPhasesStart DateCompletion DatePrimary Completion Date
NCT06727552A Study of Barzolvolimab in Patients With Atopic DermatitisRECRUITINGPHASE22025-01-072027-052026-10
NCT06650761A Phase I Study of CDX-622RECRUITINGPHASE12024-11-012026-042026-04
NCT06455202A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)RECRUITINGPHASE32024-07-192027-042026-10
NCT06445023A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous UrticariaRECRUITINGPHASE32024-07-112027-042026-10
NCT06366750A Study of Barzolvolimab in Patients With Prurigo NodularisRECRUITINGPHASE22024-04-122026-062026-01
NCT05774184A Study of CDX-0159 in Patients With Eosinophilic EsophagitisACTIVE_NOT_RECRUITINGPHASE22023-06-012025-122025-06-04
NCT05788484A Study of CDX-585 in Patients With Advanced MalignanciesCOMPLETEDPHASE12023-05-112025-05-212025-05-21
NCT05405660A Study of CDX-0159 in Patients With Chronic Inducible UrticariaACTIVE_NOT_RECRUITINGPHASE22022-06-282025-092024-06-12
NCT05368285A Phase 2 Study of CDX-0159 in Patients With Chronic Spontaneous UrticariaCOMPLETEDPHASE22022-05-192024-12-202023-09-28
NCT04944862A Study of CDX-0159 in Patients With Prurigo NodularisCOMPLETEDPHASE12021-11-082023-07-312023-07-31
NCT05031624A Phase 1 Study of Subcutaneous CDX-0159 in Healthy SubjectsCOMPLETEDPHASE12021-08-302022-01-142022-01-14
NCT04548869A Single Dose Study of the Safety, Pharmacokinetics and Pharmacodynamics of CDX-0159 in Patients With Cold Contact Urticaria, Symptomatic Dermographism, or Cholinergic UrticariaCOMPLETEDPHASE12020-11-242023-05-122022-12-16
NCT04538794A Study of CDX-0159 in Patients With Chronic Spontaneous UrticariaCOMPLETEDPHASE12020-09-242023-01-172023-01-17
NCT04440943A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced MalignanciesCOMPLETEDPHASE12020-08-042023-04-062023-04-06
NCT04146129A Phase 1 Study of CDX-0159COMPLETEDPHASE12019-10-292020-06-262020-04-06
NCT03254927A Study of CDX-3379 and Cetuximab and in Patients With Advanced Head and Neck Squamous Cell CarcinomaTERMINATEDPHASE22018-03-272020-12-162020-09-16
NCT03329950A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced MalignanciesCOMPLETEDPHASE12017-12-012022-09-132022-09-13
NCT02837991A Dose Escalation, Safety and Activity Study of CDX-014 in Patients With Renal Cell Carcinoma and Ovarian Clear Cell CarcinomaTERMINATEDPHASE12016-062018-11-162018-11-16
NCT02642016A Study to Evaluate the Safety and Pharmacokinetics of CDX-0158 in Adult Patients With Advanced Solid TumorsCOMPLETEDPHASE12015-122019-06-042018-01-30
NCT02543645A Study of Varlilumab and Atezolizumab in Patients With Advanced CancerTERMINATEDPHASE12015-102017-05-222017-04
NCT02473731A Window of Opportunity Study of KTN3379 in Surgically Resectable Head and Neck Cancer PatientsCOMPLETEDPHASE12015-102016-10-102016-09-22
NCT02456701Enhancing Radioiodine Incorporation Into BRAF Mutant Thyroid Cancers With the Combination of Vemurafenib and KTN3379COMPLETEDPHASE12015-062016-10-132016-10-13
NCT02386111A Study of Varlilumab (Anti-CD27) and Sunitinib in Patients With Metastatic Clear Cell Renal Cell CarcinomaTERMINATEDPHASE12015-052017-11-032017-08
NCT02413827A Study of Varlilumab (Anti-CD27) and Ipilimumab and CDX-1401 in Patients With Unresectable Stage III or IV MelanomaTERMINATEDPHASE1, PHASE22015-042016-11-092016-11-02
NCT02335918A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid TumorsCOMPLETEDPHASE1, PHASE22015-012018-12-122018-12-12
NCT02302339A Study of Glembatumumab Vedotin as Monotherapy or in Combination With Immunotherapies in Patients With Advanced MelanomaTERMINATEDPHASE22014-112018-10-032018-06-14
NCT02200380A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant PairsTERMINATEDPHASE22014-072016-04-132016-03
NCT02014909A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of KTN3379 in Adult Subjects With Advanced TumorsCOMPLETEDPHASE12014-012017-06-052017-05-25
NCT01997333Study of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast CancerCOMPLETEDPHASE22013-112018-08-072017-11-30
NCT01791686Clinical Trial of CDX-1135 in Pediatric and Adult Patients With Dense Deposit DiseaseTERMINATEDPHASE12013-012014-032014-03
NCT01498328A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive GlioblastomaCOMPLETEDPHASE22011-122016-05-172015-04
NCT01480479Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed GlioblastomaCOMPLETEDPHASE32011-112016-112016-11
NCT01460134A Study of CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic CancersCOMPLETEDPHASE12011-102017-10-162015-12
NCT01465139A Study to Evaluate CDX-301 (rhuFlt3L) in Healthy VolunteersCOMPLETEDPHASE12011-102013-012012-11
NCT01156753A Study of CDX-011 (CR011-vcMMAE) in Patients With Advanced GPNMB-expressing Breast CancerCOMPLETEDPHASE22010-072012-112012-10
NCT01094496A Study of the CDX-1307 Vaccine Regimen in Patients With Newly Diagnosed Muscle-Invasive Bladder Cancer (The "N-ABLE" Study)TERMINATEDPHASE22010-042011-072011-07
NCT00948961A Study of CDX-1401 in Patients With Malignancies Known to Express NY-ESO-1COMPLETEDPHASE1, PHASE22009-092014-022012-06
NCT00704158Study of CR011-vcMMAE to Treat Locally Advanced or Metastatic Breast CancerCOMPLETEDPHASE1, PHASE22008-062011-062010-11
NCT00458601Phase II Study of Rindopepimut (CDX-110) in Patients With Glioblastoma MultiformeCOMPLETEDPHASE22007-082016-052010-11
NCT00412828A Phase I/II Study of CR011-vcMMAE in Subjects With Unresectable Stage III or Stage IV MelanomaCOMPLETEDPHASE1, PHASE22006-062011-052010-12
NCT00323518A Phase II Controlled Trial of Velafermin for Prevention of Oral MucositisCOMPLETEDPHASE22006-052008-082008-08
NCT00648102Phase I Study of CDX-1307, hCG-B Vaccine, for Patients With Incurable, Locally Advanced or Metastatic Breast, Colorectal, Pancreatic, Bladder or Ovarian CancerCOMPLETEDPHASE12006-012009-122009-05
NCT00104065Safety and Efficacy of CG53135-05 in the Prevention of Oral Mucositis in Patients Receiving Bone Marrow TransplantCOMPLETEDPHASE22005-012005-122005-12
NCT00709462A Study of CDX-1307, in Patients With Incurable Breast, Colorectal, Pancreatic, Ovarian or Bladder Cancer (CDX 1307-01)COMPLETEDPHASE12004-032010-062010-05