| NCT06878976 | Open-Label Safety Study of Solriamfetol in Subjects with Binge Eating Disorder | ENROLLING_BY_INVITATION | PHASE3 | 2025-02-20 | 2026-12 | 2026-12 |
| NCT06736509 | An Open-Label Study to Assess the Long-term Safety of AXS-05 in Subjects With Dementia of the Alzheimer's Type, ADVANCE-2 and ACCORD-2 Extension Study | TERMINATED | PHASE3 | 2024-11-21 | 2025-04-25 | 2025-02-17 |
| NCT06568367 | Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN) | RECRUITING | PHASE3 | 2024-08-01 | 2026-12 | 2026-12 |
| NCT06413433 | Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol | RECRUITING | PHASE3 | 2024-04-26 | 2025-12 | 2025-12 |
| NCT06360419 | Progressing TAAR-1, Dopamine, and Norepinephrine in Depression Using Solriamfetol | COMPLETED | PHASE3 | 2024-03-18 | 2025-03-26 | 2024-12-31 |
| NCT06223880 | A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms | RECRUITING | PHASE4 | 2023-12-27 | 2026-03 | 2026-03 |
| NCT05972044 | A Study to Assess the Efficacy and Safety of Solriamfetol in Subjects With ADHD (FOCUS) | COMPLETED | PHASE3 | 2023-07-06 | 2025-03-14 | 2025-02-07 |
| NCT05557409 | A Study to Assess the Efficacy and Safety of AXS-05 in Subjects with Alzheimer's Disease Agitation | COMPLETED | PHASE3 | 2022-09-06 | 2024-12-21 | 2024-11-21 |
| NCT05550207 | Open-Label Study of AXS-07 for the Acute Treatment of Migraine in Adults With a Prior Inadequate Response to an Oral CGRP Inhibitor (EMERGE) | COMPLETED | PHASE3 | 2022-08-31 | 2024-11-27 | 2024-10-16 |
| NCT05113745 | A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects with Narcolepsy (ENCORE) | COMPLETED | PHASE3 | 2021-10-20 | 2024-11-15 | 2024-09-12 |
| NCT05059223 | A Study to Assess the Efficacy and Safety of AXS-12 (Reboxetine) in Patients With Narcolepsy | COMPLETED | PHASE3 | 2021-09-15 | 2024-03-15 | 2024-03-15 |
| NCT05008341 | Evaluate Sunosi® PK in Breast Milk and Plasma of Healthy Postpartum Women Following Single Dose Oral Administration | COMPLETED | PHASE1 | 2021-08-27 | 2022-04-15 | 2022-04-15 |
| NCT04947553 | A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitation | COMPLETED | PHASE3 | 2021-06-17 | 2024-12-21 | 2024-12-03 |
| NCT04789174 | Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study | COMPLETED | PHASE4 | 2021-05-17 | 2022-09-19 | 2022-09-19 |
| NCT04971291 | An Evaluation of AXS-05 for the Treatment of TRD in Treatment-Adherent Patients | UNKNOWN | PHASE2 | 2021-04-14 | 2021-07 | 2021-07 |
| NCT04797715 | Assessing Clinical Outcomes in Alzheimer's Disease Agitation | COMPLETED | PHASE3 | 2020-12-31 | 2022-11-21 | 2022-11-21 |
| NCT04634669 | Open-Label Safety Study of AXS-05 in Subjects With TRD (EVOLVE) | COMPLETED | PHASE2 | 2020-09-23 | 2022-03-04 | 2022-03-04 |
| NCT04608396 | Mechanistic Evaluation of Response in TRD (MERIT) | COMPLETED | PHASE2 | 2020-08-13 | 2021-07-30 | 2021-07-30 |
| NCT04163185 | Initiating Early Control of Migraine Pain and Associated Symptoms | COMPLETED | PHASE3 | 2019-10-08 | 2020-03-23 | 2020-03-23 |
| NCT04039022 | Open-Label Safety Study of AXS-05 in Subjects With Depression | COMPLETED | PHASE3 | 2019-07-08 | 2020-10-23 | 2020-10-23 |
| NCT04068051 | Multimechanistic Treatment Over Time of Migraine Symptoms (MOVEMENT) | COMPLETED | PHASE3 | 2019-07-06 | 2020-09-22 | 2020-09-22 |
| NCT04019704 | A Trial of AXS-05 in Patients With Major Depressive Disorder | COMPLETED | PHASE3 | 2019-06-20 | 2019-12-05 | 2019-11-26 |
| NCT03896009 | Maximizing Outcomes in Treating Acute Migraine | COMPLETED | PHASE3 | 2019-03-04 | 2019-12-10 | 2019-12-10 |
| NCT03881852 | Clinical Outcomes in Narcolepsy and Cataplexy: An Evaluation of Reboxetine Treatment (CONCERT) | COMPLETED | PHASE2 | 2019-01-30 | 2019-11-27 | 2019-11-27 |
| NCT03595579 | Assessing Symptomatic Clinical Episodes in Depression | COMPLETED | PHASE2 | 2018-05-30 | 2019-01-07 | 2019-01-07 |
| NCT03226522 | Addressing Dementia Via Agitation-Centered Evaluation | COMPLETED | PHASE2, PHASE3 | 2017-07-13 | 2020-04-17 | 2020-04-17 |
| NCT02741791 | A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Treatment Resistant Major Depressive Disorder | COMPLETED | PHASE3 | 2016-03 | 2020-03-20 | 2020-03-20 |
| NCT02746068 | A Study to Assess the Efficacy and Safety of AXS-02 in Subjects With Knee OA Associated With Bone Marrow Lesions | UNKNOWN | PHASE3 | 2016-03 | 2020-12 | 2020-12 |
| NCT02504008 | CREATE-1: A Study to Assess the Efficacy and Safety of AXS-02 in Patients With CRPS-1 | UNKNOWN | PHASE3 | 2015-07 | 2019-01 | 2019-01 |