Clinical Trials - AVIR

NCT IDTitleStatusPhasesStart DateCompletion DatePrimary Completion Date
NCT07037277C-Forward: Efficacy and Safety of BEM/RZR vs SOF/VEL in Subjects With Chronic HCVRECRUITINGPHASE32025-06-022027-032026-12
NCT07007806Drug-drug Interaction Study of Omeprazole and Bemnifosbuvir/RuzasvirCOMPLETEDPHASE12025-05-092025-06-282025-06-28
NCT06911320Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal or Hepatic FunctionRECRUITINGPHASE12025-04-092025-112025-11
NCT06921941Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Digoxin and RosuvastatinCOMPLETEDPHASE12025-04-082025-07-022025-07-02
NCT06868264C-BEYOND: Efficacy and Safety of BEM/RZR vs. SOF/VEL in Subjects With Chronic HCVRECRUITINGPHASE32025-04-072026-122026-09
NCT06356194Drug-drug Interaction Study of Biktarvy and Bemnifosbuvir/RuzasvirCOMPLETEDPHASE12024-04-152024-05-302024-05-30
NCT06204679Pharmacokinetics of Fixed-Dose Combination Tablet of Bemnifosbuvir and RuzasvirCOMPLETEDPHASE12023-12-142024-08-252024-08-25
NCT05904470A Phase 2, Safety and Efficacy of Bemnifosbuvir (BEM) and Ruzasvir (RZR) in Subjects with Chronic HCVCOMPLETEDPHASE22023-05-302025-01-282024-12-09
NCT05905497The Study of Bemnifosbuvir in Healthy Japanese SubjectsCOMPLETEDPHASE12023-04-262023-05-192023-05-19
NCT05905484Study of Bemnifosbuvir on Cardiac Repolarization in Healthy SubjectsCOMPLETEDPHASE12023-04-252023-05-312023-05-31
NCT05724693Study of Bemnifosbuvir in Subjects With Normal and Impaired Hepatic FunctionCOMPLETEDPHASE12023-01-302024-04-232024-04-23
NCT05731843Drug-drug Interaction Study of Ruzasvir and BemnifosbuvirCOMPLETEDPHASE12023-01-302023-03-152023-03-15
NCT05629962SUNRISE-3: Efficacy and Safety of Bemnifosbuvir in High-Risk Outpatients With COVID-19COMPLETEDPHASE32022-11-252024-05-302024-04-25
NCT05618314Study of AT-527 in Subjects With Normal and Impaired Renal FunctionCOMPLETEDPHASE12022-10-172024-06-152024-06-15
NCT05466240Study of AT-752 in Patients With Dengue InfectionTERMINATEDPHASE22022-04-292023-01-192023-01-19
NCT05366439Study of AT-752 in Healthy Subjects in a Dengue Human Challenge ModelTERMINATEDPHASE12022-04-222023-03-162023-03-16
NCT05256732Study of AT-527 in Healthy Subjects Under Fasting Conditions or With a MealCOMPLETEDPHASE12022-02-222022-08-232022-08-23
NCT05154123Drug-drug Interaction Study of Rosuvastatin and AT-527 (R07496998)COMPLETEDPHASE12021-11-162021-12-232021-12-23
NCT05137626Drug-drug Interaction Study of Digoxin and AT-527 (R07496998)COMPLETEDPHASE12021-11-032021-12-122021-12-12
NCT04309734Study of AT-777 in Healthy Subjects and AT-777 in Combination With AT-527 in HCV-Infected SubjectsWITHDRAWNPHASE1, PHASE22021-102022-092022-06
NCT05004415Mass Balance Study of AT-527 in Healthy Adult Male Subjects (R07496998)COMPLETEDPHASE12021-07-282021-08-122021-08-12
NCT04877769Bronchopulmonary PK of AT-527 (R07496998)COMPLETEDPHASE12021-04-252021-08-312021-08-31
NCT04865445Drug-drug Interaction Study of Midazolam and AT-527 (R07496998)COMPLETEDPHASE12021-04-222021-05-152021-05-15
NCT04849299Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998)COMPLETEDPHASE12021-04-182021-05-102021-05-10
NCT04722627Study of AT-752 in Healthy SubjectsCOMPLETEDPHASE12021-03-092021-11-142021-11-14
NCT04784000Effect of Carbamazepine on the Pharmacokinetics (PK) of AT-527COMPLETEDPHASE12021-03-012021-04-102021-04-10
NCT04711187Study of AT-527 in Healthy Subjects (R07496998)COMPLETEDPHASE12020-11-022021-09-152021-09-15
NCT04396106Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (COVID-19) in a Hospital SettingTERMINATEDPHASE22020-05-262022-02-282022-01-10
NCT04019717Study of AT-527 in Combination With Daclatasvir in Subjects With Hepatitis C Virus (HCV) InfectionCOMPLETEDPHASE22019-06-202020-03-232020-01-29
NCT03219957Study of AT-527 in Healthy and HCV-Infected SubjectsCOMPLETEDPHASE12017-07-062018-06-202018-06-20