| NCT07134088 | A Study of Subcutaneous Blinatumomab in Children With R/R and and MRD+ B-Cell Precursor Acute Lymphoblastic Leukemia | NOT_YET_RECRUITING | PHASE1, PHASE2 | 2025-11-21 | 2030-06-18 | 2028-12-05 |
| NCT07213674 | A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer | NOT_YET_RECRUITING | PHASE3 | 2025-11-01 | 2032-08-30 | 2028-08-29 |
| NCT07172919 | A Rollover Study Evaluating Sotorasib With or Without Panitumumab in Participants With KRAS p.G12C Mutation | NOT_YET_RECRUITING | PHASE2 | 2025-10-20 | 2027-10-20 | 2027-10-20 |
| NCT07140900 | Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer | RECRUITING | PHASE1 | 2025-10-07 | 2030-03-30 | 2028-03-27 |
| NCT07037758 | A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311) | RECRUITING | PHASE1 | 2025-09-16 | 2031-01-04 | 2028-03-04 |
| NCT06987539 | A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inebilizumab in Children With Generalized Myasthenia Gravis (gMG) | NOT_YET_RECRUITING | PHASE2 | 2025-08-29 | 2030-01-04 | 2030-01-04 |
| NCT07142642 | A Study to Evaluate Pharmacokinetics, Safety, and Tolerability of Teprotumumab (AMG 632) Administered Intravenously in Healthy Chinese Participants | ACTIVE_NOT_RECRUITING | PHASE1 | 2025-08-26 | 2025-11-22 | 2025-11-22 |
| NCT07136012 | OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events | RECRUITING | PHASE3 | 2025-08-22 | 2031-03-19 | 2031-03-19 |
| NCT07005128 | A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC) | RECRUITING | PHASE3 | 2025-08-18 | 2029-07-15 | 2029-01-04 |
| NCT07160257 | A Study to Evaluate the Effect of Maridebart Cafraglutide on Insulin Sensitivity and β-cell Function in Participants With Type 2 Diabetes Mellitus | RECRUITING | PHASE1 | 2025-08-05 | 2026-12-13 | 2026-08-26 |
| NCT07094113 | AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors | RECRUITING | PHASE1 | 2025-07-31 | 2030-09-09 | 2027-09-06 |
| NCT07037433 | Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity | RECRUITING | PHASE3 | 2025-07-25 | 2030-09-29 | 2028-06-30 |
| NCT06570798 | A Phase 2a Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases | RECRUITING | PHASE2 | 2025-07-16 | 2029-06-23 | 2028-09-15 |
| NCT07037459 | Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity | RECRUITING | PHASE3 | 2025-06-25 | 2030-09-29 | 2028-06-30 |
| NCT06987695 | Efficacy and Safety of Maridebart Cafraglutide in Adult Participants in Japan Who Have Obesity Disease | RECRUITING | PHASE3 | 2025-06-13 | 2027-10-19 | 2027-07-26 |
| NCT06588153 | A Study for the Evaluation of Efficacy and Safety of Prolia® in Participants With Glucocorticoid-induced Osteoporosis in Mainland China | RECRUITING | PHASE4 | 2025-05-24 | 2027-05-24 | 2027-05-24 |
| NCT06898957 | Study of Tarlatamab in Combination With YL201 With or Without Anti-programmed Death Ligand 1 (PD-L1) in Participants With Extensive Stage (ES) Small Cell Lung Cancer (SCLC) | RECRUITING | PHASE1 | 2025-05-16 | 2031-05-21 | 2031-05-21 |
| NCT06910709 | Single and Multiple Ascending Dose Study of AMG 378 in Healthy Participants | RECRUITING | PHASE1 | 2025-04-08 | 2028-10-04 | 2028-10-04 |
| NCT06858878 | Efficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight | ACTIVE_NOT_RECRUITING | PHASE3 | 2025-03-17 | 2027-04-25 | 2027-01-30 |
| NCT06858839 | Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight | ACTIVE_NOT_RECRUITING | PHASE3 | 2025-03-12 | 2027-04-27 | 2027-02-01 |
| NCT06745323 | A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects With SCLC | RECRUITING | PHASE2 | 2025-02-26 | 2029-02-13 | 2029-02-13 |
| NCT06747949 | A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) | RECRUITING | PHASE3 | 2025-02-25 | 2029-08-26 | 2029-08-26 |
| NCT06700343 | Comparison Between ABP 692 and Ocrevus® (Ocrelizumab) | RECRUITING | PHASE3 | 2025-01-13 | 2027-12-17 | 2027-01-15 |
| NCT06649006 | Study to Investigate Intravenous Blinatumomab in Japanese Adult Participants With Newly Diagnosed Philadelphia-negative B-precursor Acute Lymphoblastic Leukemia (B-ALL) | ACTIVE_NOT_RECRUITING | PHASE1 | 2025-01-08 | 2025-12-15 | 2025-07-30 |
| NCT06593522 | A Phase 2 Study of AMG 193 in Participants With MTAP-deleted Advanced NSCLC (MTAPESTRY 201) | RECRUITING | PHASE2 | 2024-12-26 | 2029-09-11 | 2027-09-12 |
| NCT06691984 | Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer (XALute) | RECRUITING | PHASE3 | 2024-12-09 | 2029-07-30 | 2028-12-01 |
| NCT06613100 | Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer | RECRUITING | PHASE1 | 2024-11-25 | 2030-01-23 | 2026-09-19 |
| NCT06660173 | A Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM) | ACTIVE_NOT_RECRUITING | PHASE2 | 2024-11-07 | 2026-06-25 | 2025-10-09 |
| NCT06321601 | Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV. | RECRUITING | PHASE3 | 2024-10-22 | 2030-07-20 | 2030-07-20 |
| NCT06637371 | A Phase 1, Randomized, Double-blind, Placebo-controlled Study Evaluating AMG 691 in Healthy Participants and Participants With Mild-to-Moderate Asthma | RECRUITING | PHASE1 | 2024-10-16 | 2026-10-25 | 2026-09-13 |
| NCT06411860 | A Study to Assess the Effect of Olpasiran on QT/QTc Intervals in Healthy Participants | COMPLETED | PHASE1 | 2024-10-10 | 2024-12-11 | 2024-11-29 |
| NCT06598306 | Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308) | RECRUITING | PHASE1 | 2024-10-07 | 2030-03-27 | 2027-02-01 |
| NCT06555796 | Evaluation of Xaluritamig in High-Risk, Biochemically Recurrent, Non-metastatic Castrate-sensitive Prostate Cancer | RECRUITING | PHASE1 | 2024-09-23 | 2029-06-21 | 2026-12-21 |
| NCT06333951 | AMG 193 Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104). | RECRUITING | PHASE1 | 2024-09-17 | 2031-10-27 | 2028-10-27 |
| NCT06430866 | Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab) | RECRUITING | PHASE3 | 2024-09-12 | 2027-03-15 | 2026-03-27 |
| NCT06311721 | A Study to Compare ABP 234 and Keytruda® (Pembrolizumab) in Participants With Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer | RECRUITING | PHASE3 | 2024-09-09 | 2028-05-29 | 2028-02-14 |
| NCT06585462 | Single and Multiple Ascending Dose Study of AMG 513 in Participants With Obesity | RECRUITING | PHASE1 | 2024-09-09 | 2026-07-22 | 2026-07-22 |
| NCT06502977 | Study Evaluating Tarlatamab in Chinese Participants With Advanced Small Cell Lung Cancer After Two or More Prior Lines of Treatment | ACTIVE_NOT_RECRUITING | PHASE2 | 2024-08-27 | 2026-05-11 | 2025-03-28 |
| NCT06976372 | A Study to Evaluate AMG 133 Administered Subcutaneously in Participants With Overweight or Obesity | COMPLETED | PHASE1 | 2024-08-20 | 2024-12-27 | 2024-12-27 |
| NCT06332014 | Evaluation of Efficacy and Safety of Prolia in Subjects of Male Osteoporosis in Mainland China | RECRUITING | PHASE4 | 2024-08-06 | 2027-03-31 | 2027-03-31 |
| NCT06438263 | A Study to Evaluate Bioavailability of Rocatinlimab Autoinjector and Vial in Healthy Participants | COMPLETED | PHASE1 | 2024-08-06 | 2025-05-03 | 2025-05-03 |
| NCT06054113 | Study of Blinatumomab Administration in Chinese Pediatric Participants With Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia (R/R B-ALL) | RECRUITING | PHASE2 | 2024-07-23 | 2027-12-24 | 2026-03-04 |
| NCT06527404 | A Phase 3, Placebo-controlled, Double-blind Study Assessing Rocatinlimab in Prurigo Nodularis | RECRUITING | PHASE3 | 2024-07-18 | 2027-05-14 | 2027-02-22 |
| NCT06252649 | Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation | RECRUITING | PHASE3 | 2024-07-17 | 2031-08-31 | 2028-01-31 |
| NCT06061523 | A Clinical Trial to Evaluate Bioavailability and Effect of Food for Sotorasib in Healthy Participants | WITHDRAWN | PHASE1 | 2024-07-15 | 2024-09-09 | 2024-09-09 |
| NCT06468826 | A Study of Avacopan in Participants With Normal Renal Function and Participants With End-Stage Renal Disease (ESRD) | COMPLETED | PHASE1 | 2024-07-11 | 2024-10-05 | 2024-10-05 |
| NCT06248619 | A Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in Male and Female Adult Participants With Moderate-to-severe Active Thyroid Eye Disease | ACTIVE_NOT_RECRUITING | PHASE3 | 2024-07-05 | 2026-09-29 | 2026-02-10 |
| NCT06211036 | Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and Durvalumab | RECRUITING | PHASE3 | 2024-06-05 | 2028-10-14 | 2027-07-05 |
| NCT06401044 | A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease | RECRUITING | PHASE1 | 2024-05-30 | 2027-08-13 | 2027-02-22 |
| NCT06360354 | A Study Evaluating AMG 193 in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion (MTAPESTRY 103) | RECRUITING | PHASE1 | 2024-05-29 | 2029-02-25 | 2027-02-26 |
| NCT06376045 | A Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe Asthma | RECRUITING | PHASE2 | 2024-05-24 | 2026-10-02 | 2026-08-10 |
| NCT06312020 | A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome | RECRUITING | PHASE2 | 2024-05-09 | 2027-02-09 | 2026-06-02 |
| NCT06352892 | A Study to Evaluate AMG 133 in Chinese Participants With Obesity or Overweight | COMPLETED | PHASE1 | 2024-04-25 | 2024-08-27 | 2024-08-27 |
| NCT05972551 | Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta | RECRUITING | PHASE3 | 2024-04-22 | 2027-08-25 | 2027-06-01 |
| NCT06245408 | A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State | RECRUITING | PHASE3 | 2024-04-08 | 2026-11-03 | 2026-09-02 |
| NCT06224192 | A Study With Self-administered Rocatinlimab in Adolescent and Adult Participants With Moderate-to-severe Atopic Dermatitis | ACTIVE_NOT_RECRUITING | PHASE3 | 2024-04-02 | 2026-03-15 | 2025-04-11 |
| NCT06180278 | Long-term, Open-label, Safety Study of Inebilizumab in Neuromyelitis Optica Spectrum Disorder (NMOSD) | ACTIVE_NOT_RECRUITING | PHASE4 | 2024-04-02 | 2028-06-26 | 2028-06-26 |
| NCT06229145 | A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Gout | ACTIVE_NOT_RECRUITING | PHASE4 | 2024-03-18 | 2026-04-09 | 2025-07-30 |
| NCT06131398 | A Study of AMG 355 Alone and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors | RECRUITING | PHASE1 | 2024-03-07 | 2028-12-22 | 2028-03-02 |
| NCT06117774 | Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC) | RECRUITING | PHASE3 | 2024-02-20 | 2030-03-31 | 2030-03-31 |
| NCT06268860 | A Study to Assess Bioavailability of Rocatinlimab (AMG 451) Vial and Prefilled Syringe in Healthy Participants | COMPLETED | PHASE1 | 2024-02-15 | 2024-08-30 | 2024-08-30 |
| NCT06072482 | A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis | RECRUITING | PHASE4 | 2024-02-07 | 2036-12-31 | 2036-12-31 |
| NCT06104124 | A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity | ACTIVE_NOT_RECRUITING | PHASE3 | 2024-01-24 | 2026-08-19 | 2026-06-18 |
| NCT06214481 | A Study to Evaluate Rocatinlimab (AMG 451) in Healthy Chinese Participants | COMPLETED | PHASE1 | 2024-01-23 | 2024-05-27 | 2024-05-27 |
| NCT05669014 | A Phase 2 Proof of Concept Study to Evaluate the Efficacy and Safety of Daxdilimab in Participants With Dermatomyositis (DM) or Anti-synthetase Inflammatory Myositis (ASIM) | COMPLETED | PHASE2 | 2023-12-04 | 2025-07-02 | 2025-07-02 |
| NCT06122649 | A Study to Investigate Efficacy and Safety of Apremilast 30 mg Twice Daily (BID) in Chinese Participants With Moderate to Severe Plaque-type Psoriasis (PsO) | ACTIVE_NOT_RECRUITING | PHASE3 | 2023-11-27 | 2025-12-07 | 2025-02-28 |
| NCT05920356 | A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202) | RECRUITING | PHASE3 | 2023-11-16 | 2031-06-30 | 2026-06-30 |
| NCT06054555 | A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma | RECRUITING | PHASE3 | 2023-11-02 | 2027-01-25 | 2027-01-25 |
| NCT06079476 | A Study of Romosozumab (EVENITY®) in Postmenopausal Women in India With Osteoporosis at a High Risk of Fracture. | ACTIVE_NOT_RECRUITING | PHASE4 | 2023-10-30 | 2025-10-21 | 2025-10-21 |
| NCT06088199 | A Study of Apremilast in Pediatric Participants in Children With Mild to Moderate Plaque Psoriasis | RECRUITING | PHASE3 | 2023-10-24 | 2026-07-06 | 2026-07-06 |
| NCT05323617 | Efficacy of Romiplostim in Treatment of SAA in Adults Previously Untreated With or Refractory to Immunosuppressive Therapy | WITHDRAWN | PHASE2 | 2023-08-31 | 2025-02-25 | 2025-02-25 |
| NCT04998747 | A Study of Subcutaneous (SC) AMG 701 in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) | WITHDRAWN | PHASE1 | 2023-08-29 | 2025-08-28 | 2025-08-02 |
| NCT04586660 | Study of XGEVA® (Denosumab) in Chinese Adults and Skeletally Mature Adolescents With Giant Cell Tumor of the Bone | ACTIVE_NOT_RECRUITING | PHASE4 | 2023-08-17 | 2028-03-07 | 2028-03-07 |
| NCT05975073 | A Phase 1/2 Study of AMG 193 in Combination With IDE397 in Participants With Advanced Methylthioadenosine Phosphorylase (MTAP)-Null Solid Tumors | ACTIVE_NOT_RECRUITING | PHASE1, PHASE2 | 2023-08-01 | 2026-01-05 | 2026-01-05 |
| NCT05907122 | A Study to Evaluate Similarity of ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Resected Melanoma | ACTIVE_NOT_RECRUITING | PHASE3 | 2023-07-26 | 2025-11-30 | 2025-10-04 |
| NCT05549258 | Study of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum Disorder | RECRUITING | PHASE2 | 2023-07-03 | 2027-04-13 | 2027-04-13 |
| NCT05800964 | Study to Explore the Safety, Tolerability, and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tumors | RECRUITING | PHASE1 | 2023-06-13 | 2028-02-12 | 2027-06-10 |
| NCT05899816 | A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER) | COMPLETED | PHASE3 | 2023-06-07 | 2024-11-14 | 2024-08-26 |
| NCT05891119 | Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis | COMPLETED | EARLY_PHASE1 | 2023-06-03 | 2024-12-26 | 2024-08-21 |
| NCT05882877 | A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD) | ACTIVE_NOT_RECRUITING | PHASE3 | 2023-05-31 | 2027-06-02 | 2027-06-02 |
| NCT05740566 | Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer | ACTIVE_NOT_RECRUITING | PHASE3 | 2023-05-31 | 2028-03-26 | 2025-01-29 |
| NCT05672199 | Long-term Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerative Colitis | TERMINATED | PHASE2 | 2023-04-28 | 2024-10-31 | 2024-10-31 |
| NCT05540665 | Study of Daxdilimab (HZN-7734) in Participants With Active Proliferative Lupus Nephritis (LN) | TERMINATED | PHASE2 | 2023-04-26 | 2024-01-04 | 2024-01-04 |
| NCT05704738 | A Study to Evaluate Rocatinlimab (AMG 451) in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD) | ACTIVE_NOT_RECRUITING | PHASE3 | 2023-04-20 | 2025-11-27 | 2025-09-08 |
| NCT06674941 | A Trial to Investigate Teprotumumab (High-concentration Formulation) Subcutaneous Administration in Healthy Adult Non-Japanese and Japanese Participants | COMPLETED | PHASE1 | 2023-03-24 | 2023-11-14 | 2023-11-14 |
| NCT05767047 | A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic Arthritis | RECRUITING | PHASE3 | 2023-03-23 | 2036-03-17 | 2036-03-17 |
| NCT03904069 | Study Evaluating the Safety, Tolerability, and Efficacy of FLT3 CAR-T AMG 553 in FLT3-positive Relapsed/Refractory AML | WITHDRAWN | PHASE1 | 2023-03-13 | 2030-08-07 | 2030-08-07 |
| NCT05317078 | A Phase 1 Safety, Tolerability, and Pharmacokinetics Study of AMG 794 With Claudin 6-positive Non-small Cell Lung Cancer, Epithelial Ovarian Cancer, and Other Malignant Solid Tumor Indications | TERMINATED | PHASE1 | 2023-02-28 | 2024-04-01 | 2023-12-19 |
| NCT05724199 | A Study Assessing Rocatinlimab in Combination With Topical Corticosteroid and/or Topical Calcineurin Inhibitors in Adult Participants With Moderate-to-severe Atopic Dermatitis (AD) | COMPLETED | PHASE3 | 2023-02-21 | 2024-12-04 | 2024-09-15 |
| NCT05633355 | A Study to Assess the Safety, Tolerability, and Efficacy of Rocatinlimab in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD) | COMPLETED | PHASE3 | 2023-01-30 | 2025-07-31 | 2025-07-31 |
| NCT05565560 | A Study to Assess the Efficacy and Safety of Apremilast in Japanese Pediatric Participants With Moderate to Severe Plaque Psoriasis | ACTIVE_NOT_RECRUITING | PHASE3 | 2023-01-25 | 2026-09-06 | 2025-11-25 |
| NCT05704725 | A Study to Evaluate ABP 938 and Aflibercept (Eylea®) in Participants With Chorioretinal Vascular Disease (CVD) | COMPLETED | PHASE3 | 2023-01-23 | 2023-03-24 | 2023-02-17 |
| NCT05669599 | Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity, With or Without Type 2 Diabetes Mellitus | ACTIVE_NOT_RECRUITING | PHASE2 | 2023-01-18 | 2026-01-02 | 2024-10-08 |
| NCT05591222 | Study of Daxdilimab (HZN-7734) in Participants With Moderate-to-Severe Primary Discoid Lupus Erythematosus | TERMINATED | PHASE2 | 2022-12-29 | 2025-05-08 | 2025-05-08 |
| NCT05581303 | Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial | ACTIVE_NOT_RECRUITING | PHASE3 | 2022-12-14 | 2026-12-29 | 2026-12-29 |
| NCT05651711 | A Study Assessing Rocatinlimab (AMG 451) Monotherapy in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon) | COMPLETED | PHASE3 | 2022-12-14 | 2024-08-27 | 2024-06-05 |
| NCT05209152 | AMG 176 With Azacitidine in Subjects With Myelodysplastic Syndrome /Chronic Myelomonocytic Leukemia | TERMINATED | PHASE1 | 2022-11-14 | 2023-12-19 | 2023-12-19 |
| NCT04781543 | A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis | TERMINATED | PHASE2 | 2022-11-04 | 2025-02-24 | 2025-02-24 |
| NCT05626751 | An Open-label Extension Trial of HZNP-HZN-825-301 in Adult Participants With Diffuse Cutaneous Systemic Sclerosis (Diffuse Cutaneous SSc) | TERMINATED | PHASE2 | 2022-11-04 | 2025-02-24 | 2025-02-24 |
| NCT05284747 | EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction | ACTIVE_NOT_RECRUITING | PHASE4 | 2022-10-26 | 2027-05-29 | 2027-05-29 |
| NCT05325866 | A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression | ACTIVE_NOT_RECRUITING | PHASE1, PHASE2 | 2022-09-23 | 2026-02-06 | 2026-02-06 |
| NCT05481411 | A Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Various Degrees of Hepatic Impairment | COMPLETED | PHASE1 | 2022-09-13 | 2023-05-31 | 2023-04-05 |
| NCT05489614 | A Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Normal Renal Function and Participants With Various Degrees of Renal Impairment | COMPLETED | PHASE1 | 2022-09-13 | 2023-12-19 | 2023-10-24 |
| NCT05361395 | First-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects With Extensive Stage Small Cell Lung Cancer (ES-SCLC) | ACTIVE_NOT_RECRUITING | PHASE1 | 2022-08-24 | 2028-08-28 | 2028-08-28 |
| NCT05406115 | Single and Multiple Ascending Dose Study to Evaluate AMG 786 in Healthy Participants and Participants With Obesity | COMPLETED | PHASE1 | 2022-07-26 | 2023-08-21 | 2023-08-21 |
| NCT06389578 | A Study of TEPEZZA® Treatment in Participants With Thyroid Eye Disease | COMPLETED | PHASE1 | 2022-07-14 | 2023-09-12 | 2023-02-28 |
| NCT05497557 | A Study to Evaluate the Impact of Omeprazole on the Pharmacokinetics of Sotorasib Co-administered With an Acidic Beverage in Healthy Volunteers | COMPLETED | PHASE1 | 2022-07-14 | 2022-09-08 | 2022-09-08 |
| NCT06207682 | Effect of Repeated Oral Doses of Avacopan on the Pharmacokinetics (PK) of a Single Dose of Simvastatin | COMPLETED | PHASE1 | 2022-06-28 | 2022-08-11 | 2022-08-11 |
| NCT05430854 | Study of Daxdilimab (HZN-7734) for the Treatment of Systemic Lupus Erythematosus in an Open-label Extension Study | TERMINATED | PHASE2 | 2022-06-01 | 2023-10-31 | 2023-10-31 |
| NCT05398445 | A Study Evaluating Rocatinlimab in Moderate-to-severe Atopic Dermatitis (ROCKET-IGNITE) | COMPLETED | PHASE3 | 2022-05-31 | 2025-01-13 | 2024-11-28 |
| NCT05322577 | A Study Evaluating Bemarituzumab in Combination With Other Anti-cancer Therapies in Subjects With Previously Untreated Advanced Gastric or Gastroesophageal Junction Cancer. | ACTIVE_NOT_RECRUITING | PHASE1, PHASE2 | 2022-05-17 | 2028-03-12 | 2026-01-15 |
| NCT05368103 | Study of DAXDILIMAB for the Treatment of Moderate-to-Severe Alopecia Areata | COMPLETED | PHASE2 | 2022-04-27 | 2024-01-26 | 2023-08-07 |
| NCT05198934 | Sotorasib and Panitumumab Versus Investigator's Choice for Participants With Kirsten Rat Sarcoma (KRAS) p.G12C Mutation | ACTIVE_NOT_RECRUITING | PHASE3 | 2022-04-19 | 2025-12-31 | 2025-07-16 |
| NCT05378529 | A Cross-sectional Study of Lipoprotein(a) Levels in Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD) | COMPLETED | NA | 2022-04-19 | 2023-12-30 | 2023-12-30 |
| NCT05267470 | A Study of Bemarituzumab Monotherapy and Combination With Other Anti-cancer Therapy in SqNSCLC With FGFR2b Overexpression (FORTITUDE-201) | TERMINATED | PHASE1 | 2022-03-29 | 2024-05-28 | 2024-05-28 |
| NCT05327491 | A Study in Healthy Volunteers to Compare the Pharmacokinetics of Sotorasib Administered as 1 or 2 Tablets | COMPLETED | PHASE1 | 2022-03-21 | 2022-07-17 | 2022-07-17 |
| NCT04804553 | Apremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis | RECRUITING | PHASE3 | 2022-03-17 | 2028-12-29 | 2028-03-21 |
| NCT05111626 | Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab for FGFR2b Overexpressed Untreated Advanced Gastric and Gastroesophageal Junction Cancer. | ACTIVE_NOT_RECRUITING | PHASE3 | 2022-03-14 | 2027-01-29 | 2026-01-29 |
| NCT05174065 | Phase 3, Randomized Study of Apremilast in Japanese Participants With Palmoplantar Pustulosis (PPP) | COMPLETED | PHASE3 | 2022-03-08 | 2024-06-01 | 2023-08-19 |
| NCT05052801 | Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression | ACTIVE_NOT_RECRUITING | PHASE3 | 2022-03-07 | 2026-06-20 | 2025-06-20 |
| NCT05094336 | A Study of AMG 193 in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY 101) | RECRUITING | PHASE1, PHASE2 | 2022-02-01 | 2028-11-27 | 2026-12-30 |
| NCT04987307 | Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerative Colitis | TERMINATED | PHASE2 | 2022-01-31 | 2024-10-22 | 2024-10-22 |
| NCT04933695 | A Study of Sotorasib (AMG 510) in Participants With Stage IV NSCLC Whose Tumors Harbor a KRAS p.G12C Mutation in Need of First-line Treatment | COMPLETED | PHASE2 | 2022-01-28 | 2025-05-27 | 2025-05-27 |
| NCT05060016 | A Phase 2 Study of Tarlatamab in Patients With Small Cell Lung Cancer (SCLC) | ACTIVE_NOT_RECRUITING | PHASE2 | 2021-12-01 | 2027-04-30 | 2026-04-30 |
| NCT04478994 | A Study With TEPEZZA in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc) | TERMINATED | PHASE1 | 2021-11-17 | 2022-12-08 | 2022-11-29 |
| NCT04994717 | Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia | RECRUITING | PHASE3 | 2021-11-02 | 2031-09-30 | 2027-06-24 |
| NCT05073315 | A Comparative Study Between ABP 501 and Humira® in Participants With Moderate to Severe Plaque Psoriasis | COMPLETED | PHASE3 | 2021-10-04 | 2022-12-19 | 2022-12-19 |
| NCT04885998 | AMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC) | COMPLETED | PHASE1 | 2021-09-27 | 2024-09-11 | 2023-07-12 |
| NCT05002998 | TEPEZZA® (Teprotumumab-trbw) Post-Marketing Requirement Study | ACTIVE_NOT_RECRUITING | PHASE4 | 2021-09-16 | 2026-01-05 | 2026-01-05 |
| NCT05056246 | Study of AMG 133 Administered Subcutaneously in Healthy Japanese and Caucasian Participants | COMPLETED | PHASE1 | 2021-09-10 | 2022-04-08 | 2022-04-08 |
| NCT04528082 | Apremilast Pediatric Study in Children With Active Oral Ulcers Associated With Behçet's Disease | RECRUITING | PHASE3 | 2021-09-09 | 2030-12-17 | 2030-02-07 |
| NCT04583735 | A Study Evaluating TEPEZZA® Treatment in Patients With Chronic (Inactive) Thyroid Eye Disease | COMPLETED | PHASE4 | 2021-09-02 | 2023-10-12 | 2023-03-17 |
| NCT04822298 | Study of AMG 160 in Subjects With Non-Small Cell Lung Cancer | TERMINATED | PHASE1 | 2021-08-31 | 2022-01-26 | 2021-12-08 |
| NCT04506086 | Feasibility Study to Evaluate Outpatient Blinatumomab in Subjects With Minimal Residual Disease (MRD) of B-precursor Acute Lymphoblastic Leukemia (ALL) | TERMINATED | PHASE4 | 2021-08-26 | 2024-09-16 | 2024-07-04 |
| NCT05032066 | A Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects With Idiopathic Pulmonary Fibrosis | TERMINATED | PHASE2 | 2021-08-25 | 2025-01-02 | 2024-07-22 |
| NCT05045638 | Effect of Coadministration of Sotorasib on the Pharmacokinetics of Rosuvastatin in Healthy Participants | COMPLETED | PHASE1 | 2021-08-20 | 2021-10-10 | 2021-10-10 |
| NCT05048784 | A Study to Compare the Pharmacokinetics of Two Different Tablets of Sotorasib in Healthy Participants | COMPLETED | PHASE1 | 2021-08-16 | 2022-02-18 | 2022-02-18 |
| NCT04987333 | Study of Efavaleukin Alfa in Healthy Chinese, Japanese, and Caucasian Participants | COMPLETED | PHASE1 | 2021-08-09 | 2022-10-03 | 2022-10-03 |
| NCT04987320 | A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Olpasiran in Chinese Participants With Elevated Serum Lipoprotein(a) | COMPLETED | PHASE1 | 2021-07-28 | 2022-03-18 | 2021-11-12 |
| NCT05909852 | A Study Comparing the Pharmacokinetics (PK) of ABP 501 40 mg/0.4 mL (ABP 501-HCF) and ABP 501 40 mg/0.8 ml (ABP 501-LCF) in Healthy Adult Participants | COMPLETED | PHASE1 | 2021-07-23 | 2021-11-24 | 2021-11-24 |
| NCT04948099 | A Study of Single and Multiple Ascending Doses of VIB1116 in Rheumatic Diseases | COMPLETED | PHASE1 | 2021-07-06 | 2023-07-03 | 2023-07-03 |
| NCT04825678 | A Study to Evaluate Treatment Satisfaction With Erenumab in Participants With Migraine | COMPLETED | PHASE4 | 2021-06-11 | 2023-09-28 | 2023-09-28 |
| NCT04702737 | A Study of AMG 757 in Participants With Neuroendocrine Prostate Cancer | COMPLETED | PHASE1 | 2021-06-10 | 2024-07-22 | 2024-07-22 |
| NCT04925934 | Study of VIB7734 for the Treatment of Moderate to Severely Active SLE | COMPLETED | PHASE2 | 2021-05-28 | 2023-06-09 | 2023-05-16 |
| NCT04857606 | Single Ascending Dose of AMG 609 in Participants With Non-alcoholic Fatty Liver Disease | COMPLETED | PHASE1 | 2021-05-24 | 2023-07-19 | 2023-07-19 |
| NCT04466917 | A Study of ABP 215 Versus Bevacizumab in Chinese Subjects With Advanced Non-Squamous Non-Small Cell Lung Cancer | WITHDRAWN | PHASE3 | 2021-05-15 | 2022-11-13 | 2022-11-13 |
| NCT04680637 | Efficacy and Safety of Efavaleukin Alfa in Subjects With Active Systemic Lupus Erythematosus | TERMINATED | PHASE2 | 2021-05-06 | 2023-05-22 | 2023-05-22 |
| NCT04740034 | A Study of AMG 340 in Subjects With Metastatic Castrate-Resistant Prostate Carcinoma | TERMINATED | PHASE1 | 2021-04-29 | 2024-06-24 | 2024-06-24 |
| NCT04727554 | Study of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid Tumors | COMPLETED | PHASE1 | 2021-04-29 | 2023-06-05 | 2023-06-05 |
| NCT04887064 | Pharmacokinetics of Sotorasib in Healthy Participants and Participants With Moderate or Severe Hepatic Impairment | COMPLETED | PHASE1 | 2021-04-22 | 2022-03-09 | 2022-03-09 |
| NCT04833855 | Study to Evaluate Tezepelumab in Adults With Chronic Spontaneous Urticaria | COMPLETED | PHASE2 | 2021-04-15 | 2023-04-13 | 2022-12-20 |
| NCT04761627 | A Study to Investigate Interchangeability of ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis | COMPLETED | PHASE3 | 2021-03-24 | 2023-02-28 | 2023-02-28 |
| NCT04772313 | Pegloticase and Methotrexate Co-administered in Participants With Uncontrolled Gout Who Previously Failed Pegloticase Monotherapy | COMPLETED | PHASE4 | 2021-03-08 | 2023-04-24 | 2022-08-23 |
| NCT04762498 | A Phase 4, Open-label Study of KRYSTEXXA® (Pegloticase) Co-administered With Methotrexate (MTX) in Patients With Uncontrolled Gout (FORWARD OL) | COMPLETED | PHASE4 | 2021-01-26 | 2023-12-20 | 2023-05-18 |
| NCT04545554 | Study to Evaluate Romosozumab in Children and Adolescents With Osteogenesis Imperfecta | COMPLETED | PHASE1 | 2021-01-21 | 2023-03-30 | 2023-03-30 |
| NCT04631601 | Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (mCRPC) | TERMINATED | PHASE1, PHASE2 | 2021-01-15 | 2023-10-23 | 2023-10-23 |
| NCT04521231 | A Study of Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL | RECRUITING | PHASE1, PHASE2 | 2021-01-04 | 2029-05-25 | 2027-12-24 |
| NCT04540497 | A Study of Inebilizumab Efficacy and Safety in IgG4- Related Disease | ACTIVE_NOT_RECRUITING | PHASE3 | 2020-12-04 | 2028-10-31 | 2024-04-09 |
| NCT04590586 | Study of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalized Patients | COMPLETED | PHASE3 | 2020-11-24 | 2021-08-03 | 2021-08-03 |
| NCT04607980 | A Study to Investigate ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis | COMPLETED | PHASE3 | 2020-11-11 | 2022-06-03 | 2022-01-13 |
| NCT04265755 | Biomarker and Genetic Predictors of Erenumab Treatment Response | COMPLETED | PHASE4 | 2020-10-26 | 2023-01-18 | 2023-01-18 |
| NCT04524273 | Myasthenia Gravis Inebilizumab Trial | ACTIVE_NOT_RECRUITING | PHASE3 | 2020-10-15 | 2027-11-29 | 2024-05-28 |
| NCT04511702 | Infusion Duration Study To Assess Tolerability of Pegloticase Administered With a Shorter Infusion Duration in Subjects With Uncontrolled Gout Receiving Methotrexate | COMPLETED | PHASE4 | 2020-10-02 | 2024-03-25 | 2024-01-18 |
| NCT04524455 | Blinatumomab in Combination With AMG 404 for the Treatment of Adults With Relapsed or Refractory B Cell Precursor ALL | COMPLETED | PHASE1 | 2020-10-02 | 2023-01-24 | 2023-01-24 |
| NCT04478695 | Study of AMG 330 in Combination With Pembrolizumab in Adult With Relapsed or Refractory Acute Myeloid Leukemia | TERMINATED | PHASE1 | 2020-09-29 | 2020-10-23 | 2020-10-23 |
| NCT06563856 | A Study of TEPEZZA Subcutaneous Administration in Healthy Adults | COMPLETED | PHASE1 | 2020-09-22 | 2021-05-27 | 2021-05-27 |
| NCT04362748 | Study of AMG 256 in Adult Subjects With Advanced Solid Tumors | COMPLETED | PHASE1 | 2020-09-15 | 2023-09-21 | 2023-09-21 |
| NCT04252742 | Erenumab - Comprehensive Assessment of Efficacy in (High-Frequency) Episodic Migraine | COMPLETED | PHASE4 | 2020-09-15 | 2023-10-26 | 2023-10-26 |
| NCT04478708 | Single and Multiple Ascending Dose Study of AMG 133 in Participants With Obesity | COMPLETED | PHASE1 | 2020-08-07 | 2022-11-18 | 2022-11-18 |
| NCT04191616 | Study of Early Relapsed, Lenalidomide-refractory Subjects Eligible for Carfilzomib Triplet | COMPLETED | PHASE2 | 2020-08-06 | 2024-10-01 | 2022-11-30 |
| NCT04270760 | Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction - DOSE Finding Study | COMPLETED | PHASE2 | 2020-07-28 | 2022-11-08 | 2021-12-27 |
| NCT05599828 | A Study to Evaluate the Impact of Acid-reducing Agents on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants | COMPLETED | PHASE1 | 2020-07-17 | 2020-09-13 | 2020-09-13 |
| NCT04260191 | Study of AMG 910 in Subjects With CLDN18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma | TERMINATED | PHASE1 | 2020-06-29 | 2022-06-02 | 2022-06-02 |
| NCT04270747 | A Study to Understand Effectiveness and Safety of ABP 938 Compared to Aflibercept (Eylea®) in Patients Suffering With Neovascular Age-related Macular Degeneration [Neovascular (Wet) AMD] | COMPLETED | PHASE3 | 2020-06-22 | 2023-01-30 | 2022-07-18 |
| NCT04303780 | Study to Compare AMG 510 "Proposed INN Sotorasib" With Docetaxel in Non Small Cell Lung Cancer (NSCLC) (CodeBreak 200). | ACTIVE_NOT_RECRUITING | PHASE3 | 2020-06-04 | 2026-02-25 | 2022-08-02 |
| NCT04380753 | AMG 510 Ethnic Sensitivity Study (CodeBreaK 105). | ACTIVE_NOT_RECRUITING | PHASE1 | 2020-04-28 | 2026-06-16 | 2021-12-31 |
| NCT05578859 | A Study of the Absorption, Metabolism, and Excretion of [14C]-AMG 510 Following a Single Oral Dose in Healthy Male Subjects | COMPLETED | PHASE1 | 2020-03-11 | 2020-03-24 | 2020-03-24 |
| NCT04292275 | Heart Failure Study to Evaluate Vital Signs and Overcome Low Use of Guideline-Directed Therapy by Remote Monitoring | TERMINATED | NA | 2020-03-06 | 2021-10-01 | 2021-10-01 |
| NCT05571163 | A Study to Evaluate the Relative Bioavailability of AMG 510 Administered as Tablets and as a Water Dispersion in Healthy Participants | COMPLETED | PHASE1 | 2020-03-06 | 2020-06-14 | 2020-06-14 |
| NCT04221542 | Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer | RECRUITING | PHASE1 | 2020-03-04 | 2032-03-04 | 2030-03-05 |
| NCT03937154 | Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Non-small Cell Lung Cancer (NSCLC), Ovarian Cancer, or Breast Cancer | RECRUITING | PHASE3 | 2020-02-26 | 2027-05-20 | 2026-05-20 |
| NCT04058028 | Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE) | COMPLETED | PHASE2 | 2020-02-19 | 2023-07-25 | 2023-07-25 |
| NCT04068181 | Talimogene Laherparepvec With Pembrolizumab in Melanoma Following Progression on Prior Anti-PD-1 Based Therapy (MASTERKEY-115) (Mk-3475-A07/KEYNOTE-A07). | COMPLETED | PHASE2 | 2020-01-22 | 2024-02-26 | 2021-08-19 |
| NCT04117958 | Study of AMG 199 in Subjects With MUC17-Positive Solid Tumors Including Gastric, Gastroesophageal Junction, Colorectal, and Pancreatic Cancers | TERMINATED | PHASE1 | 2020-01-20 | 2023-06-01 | 2023-06-01 |
| NCT05581992 | Study to Evaluate the Drug-drug Interaction Effect of Omeprazole on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants | COMPLETED | PHASE1 | 2020-01-06 | 2020-01-26 | 2020-01-26 |
| NCT04174677 | Safety and Tolerability of Inebilizumab, VIB4920, or the Combination in Highly Sensitized Candidates Awaiting Kidney Transplantation From a Deceased Donor | WITHDRAWN | PHASE2 | 2019-12-27 | 2022-04 | 2021-12 |
| NCT04175613 | A Long-term Extension Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque Psoriasis | ACTIVE_NOT_RECRUITING | PHASE3 | 2019-12-20 | 2025-12-16 | 2025-10-21 |
| NCT03969329 | A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis | RECRUITING | PHASE3 | 2019-12-20 | 2027-06-30 | 2027-06-30 |
| NCT04185883 | Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101) | RECRUITING | PHASE1 | 2019-12-17 | 2027-12-05 | 2026-06-16 |
| NCT04199351 | Single and Multiple Ascending Dose Study of AMG 171 in Subjects With Obesity | TERMINATED | PHASE1 | 2019-12-13 | 2021-09-10 | 2021-09-10 |
| NCT04129164 | A Study to Evaluate the Efficacy and Safety of VIB4920 in Participants With Sjögren's Syndrome | COMPLETED | PHASE2 | 2019-12-09 | 2023-03-10 | 2022-09-01 |
| NCT04163991 | A Study to Evaluate the Safety and Efficacy of VIB4920 in Participants With Rheumatoid Arthritis | COMPLETED | PHASE2 | 2019-12-09 | 2021-12-28 | 2021-12-28 |
| NCT03912337 | Effect of Erenumab-aooe on Disability and Work Productivity in Employed Subjects With Episodic Migraine | TERMINATED | PHASE4 | 2019-12-04 | 2021-07-28 | 2021-07-28 |
| NCT05568082 | A Study to Evaluate the Drug-drug Interaction Effect of Itraconazole on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants | COMPLETED | PHASE1 | 2019-12-03 | 2019-12-17 | 2019-12-17 |
| NCT05581758 | A Study to Assess the Effect of Food on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants | COMPLETED | PHASE1 | 2019-11-14 | 2019-12-09 | 2019-11-25 |
| NCT05550129 | Study to Evaluate the Drug-drug Interactions Between Metformin and AMG 510 in Healthy Participants | COMPLETED | PHASE1 | 2019-11-13 | 2019-11-25 | 2019-11-25 |
| NCT05988034 | A Study to Assess the Effect of Avacopan at Therapeutic and Supratherapeutic Doses on the QT/QTc Interval in Healthy Participants | COMPLETED | PHASE1 | 2019-11-08 | 2020-03-31 | 2020-01-22 |
| NCT05598281 | Study to Evaluate the Effect of AMG 510 on the Pharmacokinetics (PK) of Digoxin in Healthy Participants | COMPLETED | PHASE1 | 2019-11-05 | 2019-11-19 | 2019-11-19 |
| NCT05577624 | A Study to Evaluate the Drug-drug Interaction Effect of Rifampin on the Pharmacokinetics of AMG 510 in Healthy Participants | COMPLETED | PHASE1 | 2019-11-05 | 2019-12-01 | 2019-12-01 |
| NCT04046549 | A Study to Evaluate the Safety and Efficacy of Dual Costimulation Blockade With VIB4920 and Belatacept for Prophylaxis of Allograft Rejection in Adults Receiving a Kidney Transplant | COMPLETED | PHASE2 | 2019-10-30 | 2023-03-22 | 2022-07-18 |
| NCT04057937 | A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Japanese Subjects With Palmoplantar Pustulosis | COMPLETED | PHASE2 | 2019-10-16 | 2021-06-07 | 2021-01-18 |
| NCT03971071 | A Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache | COMPLETED | PHASE4 | 2019-10-07 | 2023-06-13 | 2022-12-01 |
| NCT03362177 | Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Gastrointestinal, Pancreatic, or Colorectal Cancer | COMPLETED | PHASE3 | 2019-09-30 | 2025-01-09 | 2024-01-25 |
| NCT03934684 | Study to Evaluate Safety Tolerability & Efficacy of Kyprolis (Carfilzomib) in Relapsed or Refractory Multiple Myeloma | COMPLETED | PHASE4 | 2019-09-16 | 2025-06-27 | 2023-03-23 |
| NCT04087720 | Study of Pegloticase in Participants With Uncontrolled Gout Who Have Had a Kidney Transplant | COMPLETED | PHASE4 | 2019-09-09 | 2021-09-07 | 2021-07-06 |
| NCT03832998 | Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic Migraine | ACTIVE_NOT_RECRUITING | PHASE3 | 2019-09-05 | 2026-01-09 | 2025-01-08 |
| NCT04139226 | A Study to Evaluate the Safety, Tolerability Pharmacokinetics, and Pharmacodynamics of a New Spray Dried Dispersion (SDD) Formulation of CC-11050 After Single Dose of CC-11050 and to Evaluate the Pharmacokinetics of CC-11050 Under Fasted and Fed Conditions and After Coadministration With Omeprazole | COMPLETED | PHASE1 | 2019-08-28 | 2020-02-27 | 2020-02-27 |
| NCT03836040 | Efficacy and Safety of Erenumab in Pediatric Participants With Episodic Migraine | ACTIVE_NOT_RECRUITING | PHASE3 | 2019-07-19 | 2026-10-13 | 2025-11-19 |
| NCT03930186 | A Phase 3B, Open-label, Single-arm Study of the Efficacy and Safety of Apremilast, in Subjects With Plaque Psoriasis That is Not Adequately Controlled by Topical Therapy | COMPLETED | PHASE3 | 2019-06-17 | 2020-09-25 | 2020-05-08 |
| NCT03994731 | Study of KRYSTEXXA® (Pegloticase) Plus Methotrexate in Participants With Uncontrolled Gout | COMPLETED | PHASE4 | 2019-06-13 | 2022-04-11 | 2021-03-17 |
| NCT03872401 | Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke | COMPLETED | PHASE3 | 2019-06-11 | 2025-07-25 | 2025-07-25 |
| NCT03927144 | Study of Sustained Benefit of AMG334 in Adult Episodic Migraine Patients | COMPLETED | PHASE4 | 2019-05-15 | 2022-09-30 | 2021-10-01 |
| NCT03433755 | Safety and Efficacy of Evolocumab in Addition to Optimal Stable Background Statin Therapy in Chinese Participants With Primary Hypercholesterolemia and Mixed Dyslipidemia | TERMINATED | PHASE3 | 2019-05-09 | 2020-05-09 | 2020-04-24 |
| NCT03859427 | A Study Comparing Once-weekly vs Twice-weekly Carfilzomib in Combination With Lenalidomide and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma | COMPLETED | PHASE3 | 2019-05-08 | 2023-03-31 | 2023-03-31 |
| NCT03633708 | A Study of Etelcalcetide in Pediatric Subjects With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis | RECRUITING | PHASE3 | 2019-04-29 | 2029-01-31 | 2029-01-31 |
| NCT03812224 | A Controlled Trial of Erenumab in Migraine Prevention | COMPLETED | PHASE3 | 2019-04-12 | 2020-11-25 | 2020-03-16 |
| NCT03774875 | A Study of the Impact of Apremilast (CC-10004) on Quality of Life, Efficacy, and Safety in Adults With Manifestations of Plaque Psoriasis and Impaired Quality of Life | COMPLETED | PHASE4 | 2019-03-28 | 2021-11-03 | 2021-02-01 |
| NCT03809663 | A Dose Ranging Placebo-Controlled Double-Blind Study to Evaluate the Safety and Efficacy of Tezepelumab in Atopic Dermatitis | TERMINATED | PHASE2 | 2019-03-15 | 2020-12-22 | 2020-05-12 |
| NCT03721172 | Apremilast as a Direct Treatment for Mild-to-moderate Plaque Psoriasis Versus Placebo: an Analysis of Clinical Safety and Efficacy | COMPLETED | PHASE3 | 2019-03-11 | 2020-07-24 | 2020-03-06 |
| NCT03853109 | AMG 404 in Patients With Advanced Solid Tumors | COMPLETED | PHASE1 | 2019-03-05 | 2023-11-02 | 2022-07-19 |
| NCT03836053 | Assessment of AMG 420 in Subjects With Relapsed and/or Refractory Multiple Myeloma | TERMINATED | PHASE1 | 2019-03-04 | 2022-04-21 | 2022-04-21 |
| NCT03777436 | An Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate to Severe Genital Psoriasis | COMPLETED | PHASE3 | 2019-02-11 | 2022-02-09 | 2021-09-23 |
| NCT03783026 | A Study to Evaluate the Impact of Apremilast on Magnetic Resonance Imaging (MRI) Outcomes in Adults With Psoriatic Arthritis | COMPLETED | PHASE4 | 2019-02-06 | 2022-05-11 | 2021-10-26 |
| NCT03792841 | Safety, Tolerability, Pharmacokinetics, and Efficacy of Acapatamab in Subjects With mCRPC | TERMINATED | PHASE1 | 2019-02-05 | 2023-06-29 | 2023-06-29 |
| NCT05885451 | A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of AMG 592 in Healthy Japanese Participants | COMPLETED | PHASE1 | 2019-01-29 | 2019-04-11 | 2019-04-11 |
| NCT03818607 | A Study Evaluating the Efficacy and Safety of ABP 959 Compared With Eculizumab in Adult Participants With PNH | COMPLETED | PHASE3 | 2019-01-22 | 2022-07-12 | 2022-07-12 |
| NCT03747939 | Efficacy, Safety, and Tolerability Study of Apremilast to Treat Early Oligoarticular Psoriatic Arthritis. | COMPLETED | PHASE4 | 2018-12-31 | 2023-07-05 | 2022-12-19 |
| NCT03852472 | Evaluation of Safety and Efficacy of Avacopan in Subjects With Moderate to Severe Hidradenitis Suppurativa (AURORA) | COMPLETED | PHASE2 | 2018-12-21 | 2021-03-09 | 2021-01-14 |
| NCT03701763 | Efficacy and Safety Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque Psoriasis | COMPLETED | PHASE3 | 2018-12-19 | 2023-03-27 | 2022-04-25 |
| NCT03817424 | A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis | COMPLETED | PHASE1 | 2018-12-13 | 2020-07-20 | 2020-07-20 |
| NCT03757130 | Multiple Ascending Dose Study of AMG 598 in Adults With Obesity | COMPLETED | PHASE1 | 2018-11-26 | 2019-12-16 | 2019-12-16 |
| NCT03570697 | Imaging of Coronary Plaques in Participants Treated With Evolocumab | COMPLETED | PHASE3 | 2018-11-19 | 2021-01-21 | 2020-12-18 |
| NCT03619187 | An Interventional Study to Evaluate the Effect of Ivabradine on Exercise Capacity in Heart Transplant Recipients | WITHDRAWN | PHASE3 | 2018-11-02 | 2020-02-19 | 2020-02-19 |
| NCT03571828 | Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 562 in Subjects With r/r Diffuse Large B-cell Lymphoma, Mantle Cell Lymphoma, or Follicular Lymphoma | TERMINATED | PHASE1 | 2018-10-29 | 2022-01-12 | 2022-01-12 |
| NCT03703908 | A Study of CCX140-B in Subjects With Primary FSGS and Nephrotic Syndrome | TERMINATED | PHASE2 | 2018-10-01 | 2020-06-24 | 2020-06-24 |
| NCT03635957 | Study of Pegloticase (KRYSTEXXA®) Plus Methotrexate in Patients With Uncontrolled Gout | COMPLETED | PHASE4 | 2018-09-26 | 2020-10-26 | 2019-10-23 |
| NCT03541369 | Safety, Tolerability, PK, PD, and Efficacy of AMG 427 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia | TERMINATED | PHASE1 | 2018-09-14 | 2023-02-21 | 2023-02-21 |
| NCT03392064 | A Phase 1 Study Evaluating the Safety, Tolerability and Efficacy of AMG 119 in Subjects With RR SCLC | SUSPENDED | PHASE1 | 2018-09-10 | 2027-01-14 | 2027-01-14 |
| NCT03600883 | A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100) | ACTIVE_NOT_RECRUITING | PHASE1, PHASE2 | 2018-08-27 | 2026-01-31 | 2026-01-31 |
| NCT03465540 | Safety, Tolerability, Pharmacokinetics and Efficacy of AMG 397 in Subjects With Selected Relapsed or Refractory Hematological Malignancies | TERMINATED | PHASE1 | 2018-08-17 | 2019-07-25 | 2019-07-25 |
| NCT03621605 | A Phase1 Study of VIB9600 | TERMINATED | PHASE1 | 2018-08-14 | 2019-04-08 | 2019-04-08 |
| NCT03403374 | Safety and Tolerability of Repatha® (Evolocumab) in Indian Participants With Homozygous Familial Hypercholesterolemia | COMPLETED | PHASE4 | 2018-08-04 | 2019-11-27 | 2019-11-27 |
| NCT03626662 | Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of AMG 890 in Subjects With Elevated Plasma Lipoprotein(a) | COMPLETED | PHASE1 | 2018-07-30 | 2023-04-18 | 2023-04-18 |
| NCT03638128 | Open-label Extension of Study 20130173 of Denosumab in Children and Young Adults With Osteogenesis Imperfecta | TERMINATED | PHASE3 | 2018-07-26 | 2022-03-28 | 2022-03-28 |
| NCT03512353 | A Study of Carfilzomib Plus Dexamethasone in Adults With Relapsed or Refractory Multiple Myeloma at US Community Oncology Centers | TERMINATED | PHASE2 | 2018-07-05 | 2020-01-16 | 2020-01-16 |
| NCT03298412 | Effect of Blinatumomab on Minimal Residual Disease (MRD) in Diffuse Large B-Cell Lymphoma (DLBCL) Subjects Post Autologous Hematopoietic Stem Cell Transplantation (aHSCT) | TERMINATED | PHASE2 | 2018-05-23 | 2019-09-30 | 2019-09-30 |
| NCT03410056 | Safety and Efficacy of Efavaleukin Alfa in Subjects With Active Rheumatoid Arthritis | TERMINATED | PHASE1, PHASE2 | 2018-05-22 | 2020-05-13 | 2019-12-10 |
| NCT03536754 | A Study of CCX140-B in Subjects With FSGS | COMPLETED | PHASE2 | 2018-05-17 | 2020-02-19 | 2020-02-19 |
| NCT03299244 | Head-to-Head Study of Etelcalcetide and Cinacalcet in Asian Hemodialysis Patients With Secondary Hyperparathyroidism (SHPT) | COMPLETED | PHASE3 | 2018-05-15 | 2020-04-08 | 2020-04-08 |
| NCT03164928 | Safety and Efficiency of Denosumab in Pediatric Subjects With Glucocorticoid-induced Osteoporosis | COMPLETED | PHASE3 | 2018-05-07 | 2023-12-20 | 2021-12-13 |
| NCT03499119 | AMG 334 20160172 Pediatric Migraine PK Study. | COMPLETED | PHASE1 | 2018-05-04 | 2021-11-23 | 2021-11-23 |
| NCT03422627 | Safety and Efficacy of Efavaleukin Alfa in Subjects With Steroid Refractory Chronic Graft Versus Host Disease | TERMINATED | PHASE1, PHASE2 | 2018-04-27 | 2022-10-13 | 2022-10-13 |
| NCT03296696 | Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma | TERMINATED | PHASE1 | 2018-04-18 | 2021-08-28 | 2021-07-01 |
| NCT06004934 | A Study to Evaluate the Pharmacokinetics of Avacopan (CCX168) in Participants With Mild or Moderate Hepatic Impairment | COMPLETED | PHASE1 | 2018-04-17 | 2018-09-18 | 2018-09-18 |
| NCT03461211 | Treatment of Graves' Orbitopathy to Reduce Proptosis With Teprotumumab Infusions in an Open-Label Clinical Extension Study | COMPLETED | PHASE3 | 2018-04-16 | 2021-02-17 | 2020-06-08 |
| NCT03451422 | Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Efavaleukin Alfa in Participants With Systemic Lupus Erythematosus | COMPLETED | PHASE1 | 2018-04-10 | 2021-10-12 | 2021-10-12 |
| NCT03256344 | Study of Talimogene Laherparepvec With Atezolizumab for Triple Negative Breast Cancer and Colorectal Cancer With Liver Metastases | COMPLETED | PHASE1 | 2018-03-19 | 2021-12-03 | 2020-05-26 |
| NCT03340766 | Study Investigating the Safety and Efficacy of Blinatumomab in Combination With Pembrolizumab in Adults With Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL) | COMPLETED | PHASE1 | 2018-03-16 | 2023-08-14 | 2020-11-06 |
| NCT03283098 | A Phase 1 Study to Evaluate PK, Safety and Tolerability of AMG 416 | COMPLETED | PHASE1 | 2018-03-01 | 2019-02-04 | 2019-02-04 |
| NCT03335488 | Study of Glycerol Phenylbutyrate & Sodium Phenylbutyrate in Phenylbutyrate Naïve Patients With Urea Cycle Disorders (UCDs) | COMPLETED | PHASE4 | 2018-02-20 | 2022-12-20 | 2022-07-05 |
| NCT03432533 | A Comparison of Subject-administered Romosozumab With Healthcare Provider-administered Romosozumab for Osteoporosis | COMPLETED | PHASE3 | 2018-02-06 | 2020-01-08 | 2019-04-11 |
| NCT03343847 | Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Lymphoma. | WITHDRAWN | PHASE3 | 2018-01-27 | 2021-07-17 | 2021-07-17 |
| NCT03319940 | Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC) | ACTIVE_NOT_RECRUITING | PHASE1 | 2017-12-26 | 2026-10-18 | 2025-10-18 |
| NCT03318809 | Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function | COMPLETED | PHASE1 | 2017-12-12 | 2018-04-05 | 2018-03-12 |
| NCT03287908 | A Study to Assess AMG 701 Montherapy, or in Combination With Pomalidomide, With or Without, Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma | TERMINATED | PHASE1 | 2017-11-13 | 2023-06-30 | 2023-06-30 |
| NCT03301857 | Long-term Safety Follow-up of Subjects With Giant Cell Tumor of Bone Treated With Denosumab in Study 20062004 | COMPLETED | PHASE4 | 2017-11-13 | 2023-07-27 | 2023-07-27 |
| NCT05988008 | A Study of CCX168 in Japanese and Caucasian Healthy Adult Males | COMPLETED | PHASE1 | 2017-10-23 | 2018-09-20 | 2018-01-26 |
| NCT03476239 | Efficacy and Safety of the BiTE Antibody Blinatumomab in Chinese Adult Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (ALL) | COMPLETED | PHASE3 | 2017-10-18 | 2021-04-08 | 2019-08-21 |
| NCT03298867 | Treatment of Graves' Orbitopathy (Thyroid Eye Disease) to Reduce Proptosis With Teprotumumab Infusions in a Randomized, Placebo-Controlled, Clinical Study | COMPLETED | PHASE3 | 2017-10-04 | 2020-11-30 | 2019-02-13 |
| NCT03301467 | Controlled Trial Evaluating Avacopan in C3 Glomerulopathy | COMPLETED | PHASE2 | 2017-09-29 | 2021-10-27 | 2021-03-03 |
| NCT03456856 | A Study of Ivabradine in African-American/ Black Subjects With Heart Failure and Left Ventricular Systolic Dysfunction. | COMPLETED | PHASE4 | 2017-09-28 | 2019-05-20 | 2019-04-19 |
| NCT02961881 | A Phase 1b Open-Label Study Investigating the Safety and Pharmacokinetics of Administration of Subcutaneous Blinatumomab for the Treatment of Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma | COMPLETED | PHASE1 | 2017-09-18 | 2021-09-02 | 2021-09-02 |
| NCT03224819 | Study of Emerfetamab (AMG 673) in Adults With Relapsed/Refractory Acute Myeloid Leukemia (AML) | TERMINATED | EARLY_PHASE1 | 2017-09-07 | 2020-12-28 | 2020-12-28 |
| NCT03238781 | Study to Evaluate the Efficacy and Safety of AMG 301 in Migraine Prevention | COMPLETED | PHASE2 | 2017-09-06 | 2019-02-04 | 2018-10-16 |
| NCT02756845 | Study of Talimogene Laherparepvec In Children With Advanced Non CNS Tumors | COMPLETED | PHASE1 | 2017-08-16 | 2022-11-29 | 2022-01-17 |
| NCT03156023 | Multiple Ascending Doses of Rozibafusp Alfa (AMG 570) in Adults With Rheumatoid Arthritis | COMPLETED | PHASE1 | 2017-08-14 | 2020-06-12 | 2019-10-17 |
| NCT03158688 | Study of Carfilzomib, Daratumumab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma. | COMPLETED | PHASE3 | 2017-06-13 | 2022-04-15 | 2019-07-14 |
| NCT05913115 | A Study Evaluating Safety and Pharmacokinetics of FPA144 in Japanese Patients With Advanced Gastric or Gastroesophageal Cancer | COMPLETED | PHASE1 | 2017-06-12 | 2018-06-19 | 2018-06-19 |
| NCT02833844 | Safety, Tolerability and Efficacy on Low Density Lipoprotein Cholesterol (LDL-C) of Evolocumab in Participants With Human Immunodeficiency Virus (HIV) and Hyperlipidemia/Mixed Dyslipidemia | COMPLETED | PHASE3 | 2017-05-22 | 2020-01-27 | 2019-07-09 |
| NCT03123471 | A Study of the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Moderate to Severe Plaque Psoriasis of the Scalp | COMPLETED | PHASE3 | 2017-05-16 | 2019-01-09 | 2018-08-13 |
| NCT03170193 | AMG 529 First in Human Study | COMPLETED | PHASE1 | 2017-05-15 | 2017-11-17 | 2017-11-17 |
| NCT03029234 | Carfilzomib in Combination With Dexamethasone (Kd) in Chinese Patients With Relapsed & Refractory Multiple Myeloma | COMPLETED | PHASE3 | 2017-03-31 | 2021-06-04 | 2018-11-05 |
| NCT02994927 | A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis | COMPLETED | PHASE3 | 2017-03-15 | 2019-11-01 | 2019-09-07 |
| NCT02833857 | A Single-dose Study in Paediatric Patients Aged 2 to Less Than 18 Years With Secondary Hyperparathyroidism (sHPT) Receiving Haemodialysis | COMPLETED | PHASE1 | 2017-03-14 | 2018-10-31 | 2018-10-31 |
| NCT03080935 | Fourier Open-label Extension Study in Subjects With Clinically Evident Cardiovascular Disease in Selected European Countries | TERMINATED | PHASE3 | 2017-03-13 | 2022-03-04 | 2022-03-04 |
| NCT03023878 | Safety and Efficacy of Blinatumomab in Adults With Newly Diagnosed High-risk Diffuse Large B-Cell Lymphoma | COMPLETED | PHASE2 | 2017-03-13 | 2019-10-28 | 2019-04-04 |
| NCT03064763 | Study to Evaluate the Safety/ Efficacy of T-VEC in Japanese Subjects With Unresectable Stage IIIB-IV Malignant Melanoma | COMPLETED | PHASE1 | 2017-03-07 | 2023-01-12 | 2020-08-03 |
| NCT02910063 | Study to Evaluate Safety and Efficacy of Blinatumomab in Subjects With Relapsed/Refractory (R/R) Aggressive B-Cell NHL | COMPLETED | PHASE2, PHASE3 | 2017-01-23 | 2020-03-12 | 2020-03-12 |
| NCT02939183 | Phase 1b Study Evaluating OPomD in Relapsed or Refractory Multiple Myeloma | COMPLETED | PHASE1 | 2017-01-17 | 2022-10-06 | 2022-10-06 |
| NCT02791516 | A Safety and Efficacy Study to Evaluate Romosozumab (AMG 785) in South Korean Women With Osteoporosis | COMPLETED | PHASE3 | 2017-01-16 | 2018-12-21 | 2018-02-12 |
| NCT02986139 | Study to Assess the Injection Site Pain Associated With a New Etanercept Formulation in Adults With Rheumatoid Arthritis or Psoriatic Arthritis | COMPLETED | PHASE3 | 2016-11-29 | 2017-10-09 | 2017-09-08 |
| NCT02937701 | Study to Assess if ABP710 is Safe & Effective in Treating Moderate to Severe Rheumatoid Arthritis Compared to Infliximab | COMPLETED | PHASE3 | 2016-10-10 | 2018-08-13 | 2018-04-16 |
| NCT02624869 | Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia) | COMPLETED | PHASE3 | 2016-09-10 | 2021-06-01 | 2021-06-01 |
| NCT02867813 | Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk Open-label Extension | COMPLETED | PHASE3 | 2016-09-02 | 2022-03-21 | 2022-03-21 |
| NCT02780674 | A Phase 1 Study of MEDI7734 in Type I Interferon-Mediated Autoimmune Diseases | COMPLETED | PHASE1 | 2016-08-26 | 2017-11-27 | 2017-10-23 |
| NCT02777554 | A Study to Evaluate the Pharmacokinetic Exposure of 2 Formulations of Apremilast in Healthy Adults | COMPLETED | PHASE1 | 2016-08-17 | 2016-11-22 | 2016-11-22 |
| NCT03276728 | Study to Evaluate the Safety and Tolerability of AMG 986 in Healthy Volunteers and Heart Failure Patients | TERMINATED | PHASE1 | 2016-08-12 | 2019-04-18 | 2019-04-18 |
| NCT02797080 | Long-Term Safety Extension Study of ACTIMMUNE® (Interferon γ-1b) in Children and Young Adults With Friedreich's Ataxia | COMPLETED | PHASE3 | 2016-06-28 | 2017-03-31 | 2017-03-31 |
| NCT02802735 | Study to Evaluate the Pharmacokinetics of Single and Multiple Doses of Apremilast in Healthy Adult Male Korean Subjects | COMPLETED | PHASE1 | 2016-06-22 | 2016-08-05 | 2016-08-05 |
| NCT02675452 | AMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Participants With Relapsed or Refractory Acute Myeloid Leukemia | TERMINATED | PHASE1 | 2016-06-13 | 2024-05-27 | 2024-05-27 |
| NCT02747043 | Study to Assess if ABP798 is Safe & Effective in Treating Non Hodgkin Lymphoma Compared to Rituximab | COMPLETED | PHASE3 | 2016-05-25 | 2019-06-28 | 2019-06-28 |
| NCT02749370 | Study to Evaluate the Efficacy of Etanercept Treatment in Adults Who Failed Therapy With Apremilast | COMPLETED | PHASE4 | 2016-05-18 | 2017-12-06 | 2017-08-14 |
| NCT02792699 | Study to Assess if ABP 798 is Safe & Effective in Treating Moderate to Severe Rheumatoid Arthritis (RA) Compared to Rituximab | COMPLETED | PHASE3 | 2016-05-17 | 2018-10-08 | 2018-10-08 |
| NCT02739984 | Evaluation of Evolocumab (AMG 145) Efficacy in Diabetic Adults With Hypercholesterolemia/Mixed Dyslipidemia | COMPLETED | PHASE3 | 2016-05-17 | 2017-08-03 | 2017-08-03 |
| NCT02780388 | A Phase 1b Study of MEDI4920 in Participants With Adult-onset Rheumatoid Arthritis | COMPLETED | PHASE1 | 2016-05-12 | 2018-08-09 | 2018-05-21 |
| NCT02729025 | Effects of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition on Arterial Wall Inflammation in Patients With Elevated Lipoprotein(a) (Lp(a)) | COMPLETED | PHASE3 | 2016-04-14 | 2018-04-05 | 2018-04-05 |
| NCT02662569 | Safety and Efficacy of Evolocumab in Combination With Statin Therapy in Adults With Diabetes and Hyperlipidemia or Mixed Dyslipidemia | COMPLETED | PHASE3 | 2016-04-14 | 2017-12-06 | 2017-12-06 |
| NCT02633020 | Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease | COMPLETED | PHASE2 | 2016-04-13 | 2017-05-02 | 2017-04-11 |
| NCT02637141 | A Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Celiac Disease | COMPLETED | PHASE2 | 2016-04-13 | 2017-03-14 | 2017-02-15 |
| NCT02626000 | Talimogene Laherparepvec With Pembrolizumab for Recurrent Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY232 / KEYNOTE-137) | COMPLETED | PHASE1 | 2016-04-06 | 2020-08-28 | 2017-11-02 |
| NCT01428154 | Study to Evaluate Darbepoetin Alfa in Pediatric Subjects With Anemia Due to Chronic Kidney Disease | WITHDRAWN | PHASE1 | 2016-04 | 2016-11 | 2016-11 |
| NCT02618967 | Single Ascending Dose Study of AMG 570 in Healthy Subjects | COMPLETED | PHASE1 | 2016-03-28 | 2018-12-03 | 2018-09-06 |
| NCT02392559 | Trial Assessing Efficacy, Safety and Tolerability of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition in Paediatric Subjects With Genetic Low-Density Lipoprotein (LDL) Disorders | COMPLETED | PHASE3 | 2016-03-24 | 2019-11-25 | 2019-11-25 |
| NCT02634580 | Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-4 | COMPLETED | PHASE3 | 2016-02-27 | 2018-05-26 | 2017-08-10 |
| NCT02741310 | Study to Evaluate the Effect of Erenumab on Blood Pressure When Given Concomitantly With Subcutaneous Sumatriptan | COMPLETED | PHASE1 | 2016-02-22 | 2016-08-11 | 2016-08-11 |
| NCT02792517 | Erenumab (AMG 334) Plus Combined Oral Contraceptive Drug Interaction Study in Healthy Females | COMPLETED | PHASE1 | 2016-02-12 | 2016-09-09 | 2016-09-09 |
| NCT02509507 | Trial to Evaluate the Safety of Talimogene Laherparepvec Injected Into Tumors Alone and in Combination With Systemic Pembrolizumab MK-3475-611/Keynote-611 | COMPLETED | PHASE1, PHASE2 | 2016-02-05 | 2023-07-11 | 2022-02-14 |
| NCT06004947 | A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications | COMPLETED | PHASE1 | 2016-01-14 | 2016-06-10 | 2016-03-15 |
| NCT02630459 | A Safety and Efficacy Study to Evaluate AMG 334 in Migraine Prevention | COMPLETED | PHASE2 | 2016-01-06 | 2019-06-05 | 2017-09-25 |
| NCT02641353 | Study to Evaluate Bioavailability of Apremilast Oral Suspension Relative to Tablet and to Assess Effect of Food on the Pharmacokinetics (PK) of the Oral Suspension | COMPLETED | PHASE1 | 2016-01-05 | 2016-02-27 | 2016-02-27 |
| NCT02593773 | Safety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia Study | COMPLETED | PHASE3 | 2015-12-25 | 2017-03-21 | 2017-03-21 |
| NCT02576652 | Bone Histomorphometry in Postmenopausal Men and Women With Osteoarthritis Undergoing Total Hip Replacement | COMPLETED | PHASE4 | 2015-12-22 | 2017-12-18 | 2017-12-18 |
| NCT02585895 | Evolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study Enrollment | COMPLETED | PHASE3 | 2015-12-21 | 2017-01-20 | 2016-09-01 |
| NCT05988021 | A Study in Healthy Volunteers to Evaluate the Pharmacokinetic Food Effect and Cardiac Safety of CCX168 | COMPLETED | PHASE1 | 2015-12-03 | 2016-05-25 | 2016-02-09 |
| NCT02575833 | Treadmill Cardiovascular Safety Study of Erenumab (AMG 334) | COMPLETED | PHASE2 | 2015-11-23 | 2017-04-13 | 2017-01-23 |
| NCT02561962 | A Phase 1 Study in Subjects With Relapsed or Refractory Multiple Myeloma | COMPLETED | PHASE1 | 2015-11-20 | 2022-04-21 | 2018-11-30 |
| NCT02542605 | To Evaluate the Blockade of CGRP in Preventing PACAP-38 Induced Migraine-like Attacks With AMG 334 in Migraine Patients | COMPLETED | PHASE1 | 2015-11-11 | 2017-11-08 | 2017-09-28 |
| NCT02393859 | Phase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse B-precursor Acute Lymphoblastic Leukemia (ALL) | COMPLETED | PHASE3 | 2015-11-10 | 2022-11-21 | 2019-07-17 |
| NCT05873907 | A Study to Evaluate the Safety, Tolerability, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of AMG 592 in Healthy Participants | COMPLETED | PHASE1 | 2015-10-19 | 2017-07-28 | 2017-06-16 |
| NCT02576678 | A Study of Safety, Tolerability and Pharmacokinetics of Apremilast (CC-10004) in Pediatric Subjects With Moderate to Severe Plaque Psoriasis | COMPLETED | PHASE2 | 2015-10-13 | 2019-07-29 | 2017-09-04 |
| NCT02412878 | Once-weekly Versus Twice-weekly Carfilzomib in Combination With Dexamethasone in Adults With Relapsed and Refractory Multiple Myeloma | COMPLETED | PHASE3 | 2015-09-09 | 2019-01-07 | 2017-06-15 |
| NCT02520427 | A Phase 1 Study of AMG 330 in Subjects With Myeloid Malignancies | TERMINATED | PHASE1 | 2015-08-31 | 2022-01-09 | 2022-01-09 |
| NCT02504476 | Multiple Ascending Dose Study on Safety, Tolerability, and Pharmacokinetics of AMG 581 in Healthy Subjects or Subjects With Schizophrenia or Schizoaffective | COMPLETED | PHASE1 | 2015-08 | 2016-02 | 2016-02 |
| NCT02567370 | Single-ascending Dose Study With a Food-Effect Cohort to Evaluate AMG 581 | COMPLETED | PHASE1 | 2015-08 | 2015-10 | 2015-10 |
| NCT02483585 | Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) Compared to Placebo in Migraine Prevention | COMPLETED | PHASE3 | 2015-07-20 | 2017-03-20 | 2016-07-11 |
| NCT02456740 | Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Migraine Prevention | COMPLETED | PHASE3 | 2015-07-17 | 2017-06-19 | 2016-09-05 |
| NCT02352753 | Multicenter,Single-arm Study to Evaluate Efficacy, Safety, & Pharmacokinetics of Denosumab in Children w/ OI | TERMINATED | PHASE3 | 2015-06-24 | 2022-03-26 | 2022-03-26 |
| NCT02341417 | Extension Study of Cinacalcet for Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Patients With Chronic Kidney Disease on Dialysis | COMPLETED | PHASE3 | 2015-06-10 | 2017-03-15 | 2017-03-15 |
| NCT02412306 | Study of Blinatumomab in Japanese Patients With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia | COMPLETED | PHASE1, PHASE2 | 2015-06-04 | 2019-07-04 | 2019-02-06 |
| NCT02415127 | Safety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia | COMPLETED | PHASE3 | 2015-06 | 2016-11 | 2016-11 |
| NCT02473445 | A Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Capsules (RP103) in Children With Inherited Mitochondrial Disease | TERMINATED | PHASE2 | 2015-05-19 | 2017-03-06 | 2017-03-06 |
| NCT02429882 | Study of Efficacy and Safety of Brodalumab Compared With Placebo in Subjects With Axial Spondyloarthritis | WITHDRAWN | PHASE2 | 2015-05 | 2015-05 | 2015-05 |
| NCT02335983 | Phase 1b Study of Weekly Carfilzomib in Combination With Lenalidomide and Dexamethasone in Subjects With Multiple Myeloma | COMPLETED | PHASE1 | 2015-04-30 | 2019-10-28 | 2019-10-28 |
| NCT02437916 | Safety Study of AMG 228 to Treat Solid Tumors | TERMINATED | PHASE1 | 2015-04-21 | 2016-12-12 | 2016-12-12 |
| NCT02425826 | A Phase 4 Study of Efficacy and Safety of Apremilast in Subjects With Moderate Plaque Psoriasis. | COMPLETED | PHASE4 | 2015-04-20 | 2016-11-22 | 2016-02-12 |
| NCT02366195 | Single-arm Trial to Evaluate the Role of the Immune Response to Talimogene Laherparepvec in Unresected Melanoma | COMPLETED | PHASE2 | 2015-04-07 | 2020-12-25 | 2017-06-26 |
| NCT02253654 | Evaluation of Two Epoetin Alfa Dosing Strategies in Subjects With Chronic Kidney Disease Receiving Hemodialysis | COMPLETED | PHASE4 | 2015-04-01 | 2016-05-25 | 2016-04-27 |
| NCT02346877 | Evaluate Effects of Personalized Patient Counselling for Enbrel® Therapy in Adults With Rheumatoid Arthritis | TERMINATED | PHASE4 | 2015-04 | 2015-10 | 2015-10 |
| NCT02499315 | Study to Evaluate the Safety, Tolerability, and Action of AMG 357 in Females With Rheumatoid Arthritis | TERMINATED | PHASE1 | 2015-04 | 2016-02 | 2016-02 |
| NCT02384317 | Open-Label Study to Evaluate Safety and Efficacy of CCX168 in Subjects With IGA Nephropathy on Stable RAAS Blockade | COMPLETED | PHASE2 | 2015-03-27 | 2018-06-01 | 2015-09-13 |
| NCT02376790 | Etanercept and Methotrexate in Combination or as Monotherapy in Psoriatic Arthritis | COMPLETED | PHASE3 | 2015-03-03 | 2018-07-06 | 2018-01-09 |
| NCT02373813 | Study of Etanercept Monotherapy vs Methotrexate Monotherapy for Maintenance of Rheumatoid Arthritis Remission | COMPLETED | PHASE3 | 2015-02-20 | 2019-12-06 | 2019-12-06 |
| NCT02303821 | Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia | COMPLETED | PHASE1 | 2015-02-16 | 2024-06-28 | 2024-06-28 |
| NCT02222155 | Clinical Trial to Evaluate Safety and Efficacy of CCX168 in ANCA-Associated Vasculitis | COMPLETED | PHASE2 | 2015-02-04 | 2016-07-19 | 2016-04-24 |
| NCT02211131 | Efficacy and Safety of Talimogene Laherparepvec Neoadjuvant Treatment Plus Surgery Versus Surgery Alone for Melanoma | COMPLETED | PHASE2 | 2015-02-03 | 2022-04-28 | 2019-04-30 |
| NCT02345408 | Phase 1b Study of CCX872-B in Patients With Pancreatic Adenocarcinoma | COMPLETED | PHASE1 | 2015-02 | 2020-05-06 | 2020-05-06 |
| NCT02289417 | Efficacy and Safety Study of Apremilast to Treat Active Ulcerative Colitis | COMPLETED | PHASE2 | 2015-01-08 | 2019-06-03 | 2017-09-25 |
| NCT02274792 | Study to Assess the Immunogenicity and Safety of Etanercept Produced Using a Modified Process in Patients With Plaque Psoriasis | COMPLETED | PHASE4 | 2015-01 | 2015-11 | 2015-11 |
| NCT02246218 | A Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 Years of Age With Urea Cycle Disorders | COMPLETED | PHASE4 | 2014-12-31 | 2017-07-17 | 2016-10-17 |
| NCT02307513 | A Phase 3 Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Active Behçet's Disease | COMPLETED | PHASE3 | 2014-12-30 | 2020-07-17 | 2017-09-25 |
| NCT02279173 | Long-term Study of Romiplostim in Thrombocytopenic Pediatric Patients With Immune Thrombocytopenia (ITP) | COMPLETED | PHASE3 | 2014-12-10 | 2019-08-08 | 2018-08-30 |
| NCT02263508 | Pembrolizumab With Talimogene Laherparepvec or Placebo in Unresected Melanoma | TERMINATED | PHASE3 | 2014-12-08 | 2021-03-11 | 2021-03-11 |
| NCT02227914 | Phase 1b/2 Study of Oprozomib in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma | WITHDRAWN | PHASE1, PHASE2 | 2014-12 | 2015-03 | 2015-03 |
| NCT02291614 | A Phase 1 Study of AMG 211 in Participants With Advanced Gastrointestinal Cancer | TERMINATED | PHASE1 | 2014-11-27 | 2018-01-09 | 2017-11-06 |
| NCT05995691 | Study to Determine the Pharmacokinetic (PK) Bioequivalence of ABP 501 and Adalimumab (Humira®) in Healthy Adult Japanese Participants | COMPLETED | PHASE1 | 2014-11-24 | 2015-12-04 | 2015-12-04 |
| NCT02304484 | Open-label Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab | COMPLETED | PHASE3 | 2014-11-24 | 2018-03-09 | 2018-03-09 |
| NCT02138838 | Efficacy and Safety of Cinacalcet in Pediatric Patients With Secondary Hyperparathyroidism (SHPT) and Chronic Kidney Disease (CKD) on Dialysis | TERMINATED | PHASE3 | 2014-11-07 | 2016-06-23 | 2016-06-23 |
| NCT02101164 | Evaluate Time Associated With the Preparation & Administration of Denosumab/Pamidronate in Patients With Solid Tumors and Metastatic Bone Disease | WITHDRAWN | PHASE4 | 2014-11 | 2014-11 | 2014-11 |
| NCT06004960 | A Study to Assess the Mass Balance Recovery (Absorption, Distribution, Metabolism and Excretion) of [14C]CCX168 in Healthy Participants | COMPLETED | PHASE1 | 2014-10-20 | 2014-12-05 | 2014-12-05 |
| NCT02103283 | A Phase 1, Open-Label Study of Teprotumumab in Patients With Diabetic Macular Edema (DME) | COMPLETED | PHASE1 | 2014-10 | 2016-08 | 2016-08 |
| NCT02207634 | Evaluating PCSK9 Binding antiBody Influence oN coGnitive HeAlth in High cardiovascUlar Risk Subjects | COMPLETED | PHASE3 | 2014-09-10 | 2016-11-11 | 2016-11-11 |
| NCT02275156 | Estimation Study to Assess the Effect of Severe Renal Impairment and End-stage Renal Disease Hemodialysis on the Pharmacokinetics of Evolocumab | COMPLETED | PHASE1 | 2014-08-19 | 2014-12-19 | 2014-12-19 |
| NCT02244112 | A Phase 1 Study of Oprozomib to Assess Food Effect, Drug-Drug Interaction With Midazolam, and Safety and Tolerability in Patients With Advanced Malignancies | TERMINATED | PHASE1 | 2014-08 | 2019-07-10 | 2015-05-15 |
| NCT01999335 | A Study of Oprozomib, Pomalidomide, and Dexamethasone in Adults With Primary Refractory or Relapsed and Refractory Multiple Myeloma | TERMINATED | PHASE1 | 2014-07-30 | 2019-04-25 | 2019-04-25 |
| NCT02189837 | Effects on Lipoprotein Metabolism From PCSK9 Inhibition Utilizing a Monoclonal Antibody | COMPLETED | PHASE3 | 2014-07-08 | 2015-03-05 | 2015-02-13 |
| NCT02170337 | A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Subjects and Subjects With Chronic Rhinosinusitis With Nasal Polyps | COMPLETED | PHASE1 | 2014-07 | 2016-05 | 2016-05 |
| NCT02137343 | A Phase 3 Study of Rilotumumab (AMG 102) With Cisplatin and Capecitabine (CX) as First-line Therapy in Gastric Cancer | TERMINATED | PHASE3 | 2014-07 | 2015-06 | 2015-06 |
| NCT02174861 | A Study to Assess the Long-term Safety and Efficacy of Erenumab (AMG 334) in Chronic Migraine Prevention. | COMPLETED | PHASE2 | 2014-06-30 | 2017-05-26 | 2017-05-26 |
| NCT02186171 | A Study to Compare the Safety and Efficacy of Romosozumab (AMG 785) Versus Placebo in Men With Osteoporosis | COMPLETED | PHASE3 | 2014-06-16 | 2016-04-20 | 2016-02-15 |
| NCT02175277 | Darbepoetin Alfa MDS Companion Protocol | COMPLETED | PHASE3 | 2014-06-12 | 2017-03-20 | 2017-03-20 |
| NCT02087943 | Efficacy and Safety Study of Apremilast in Subjects With Moderate to Severe Atopic Dermatitis | COMPLETED | PHASE2 | 2014-06 | 2016-02 | 2015-10 |
| NCT02023866 | Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease | COMPLETED | PHASE2 | 2014-05 | 2016-10 | 2016-10 |
| NCT02157948 | A Double-blind Study to Assess the Efficacy and Safety of Denosumab Produced by Two Different Processes in Postmenopausal Women With Osteoporosis | COMPLETED | PHASE3 | 2014-05 | 2015-07 | 2015-07 |
| NCT02132429 | Phase I, Double-Blind,Placebo, MAD Study to Evaluate the Safety, Tolerability, PK, and PD of AMG 333 in Healthy Subjects and Migraine Subjects | TERMINATED | PHASE1 | 2014-05 | 2014-12 | 2014-10 |
| NCT02096666 | A Phase 1/2 Study Evaluating AMG 337 in Asian Subjects | COMPLETED | PHASE1, PHASE2 | 2014-04-15 | 2018-12-07 | 2015-11-05 |
| NCT02014441 | Single-arm Trial to Evaluate the Biodistribution and Shedding of Talimogene Laherparepvec | COMPLETED | PHASE2 | 2014-04-07 | 2018-04-19 | 2016-01-25 |
| NCT02114931 | Long-term Safety and Efficacy of ABP 501 in Subjects With Moderate to Severe Rheumatoid Arthritis | COMPLETED | PHASE3 | 2014-04 | 2016-04 | 2016-04 |
| NCT02099461 | Effect of Denosumab on Cellular Biomarkers in the Human Breast | COMPLETED | PHASE1 | 2014-04 | 2014-07 | 2014-07 |
| NCT02102204 | Extension Study of Etelcalcetide for Treatment of Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease on Hemodialysis | COMPLETED | PHASE3 | 2014-03-25 | 2017-06-26 | 2016-11-04 |
| NCT02066415 | A Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Chronic Migraine Prevention | COMPLETED | PHASE2 | 2014-03-05 | 2016-04-28 | 2016-02-24 |
| NCT02054572 | Pharmacokinetics and Excretion of [¹⁴C]Etelcalcetide (AMG 416) in Patients With End Stage Renal Disease (ESRD) Receiving Dialysis | COMPLETED | PHASE1 | 2014-02-07 | 2014-08-15 | 2014-04-15 |
| NCT02053753 | Bioequivalence Study of Denosumab CP4 Drug Product and Commercially Available Denosumab CP2 Drug Product | COMPLETED | PHASE1 | 2014-02 | 2014-08 | 2014-08 |
| NCT02016534 | Phase 2 Study of AMG 337 in MET Amplified Gastric/Esophageal Adenocarcinoma or Other Solid Tumors | TERMINATED | PHASE2 | 2014-02 | 2016-10 | 2016-10 |
| NCT02236988 | Study to Evaluate Pharmacokinetics of Prototype Modified-Release Formulations Of Apremilast in Healthy Men | COMPLETED | PHASE1 | 2014-01-07 | 2014-09-11 | 2014-09-11 |
| NCT02000427 | Blinatumomab in Adults With Relapsed/Refractory Philadelphia Positive B-precursor Acute Lymphoblastic Leukemia | COMPLETED | PHASE2 | 2014-01-03 | 2017-01-06 | 2015-05-20 |
| NCT02013167 | Blinatumomab Versus Standard of Care Chemotherapy in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL) | TERMINATED | PHASE3 | 2014-01-03 | 2017-03-14 | 2015-12-29 |
| NCT02072863 | A Study of Oprozomib, Melphalan, and Prednisone in Transplant Ineligible Patients With Newly Diagnosed Multiple Myeloma | COMPLETED | PHASE1, PHASE2 | 2014-01 | 2015-09 | 2015-01 |
| NCT01949532 | Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Multiple Myeloma and Renal Disease | COMPLETED | PHASE1 | 2014-01 | 2017-01 | 2015-04 |
| NCT01951586 | Denosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer | COMPLETED | PHASE2 | 2013-12-31 | 2017-11-28 | 2016-07-29 |
| NCT01984424 | Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-3 | COMPLETED | PHASE3 | 2013-12-10 | 2017-11-21 | 2015-11-10 |
| NCT02016716 | A Randomized Phase 3 Study to Evaluate Two Formulations of Romosozumab in Postmenopausal Women With Osteoporosis | COMPLETED | PHASE3 | 2013-12-03 | 2014-12-08 | 2014-09-08 |
| NCT01966003 | Efficacy and Safety Study of ABP 215 Compared With Bevacizumab in Patients With Advanced Non-Small Cell Lung Cancer | COMPLETED | PHASE3 | 2013-11-11 | 2015-07-23 | 2015-07-23 |
| NCT01987232 | Phase 1b/2 Study of Carfilzomib, Carboplatin, and Etoposide in Patients With Previously Untreated Extensive Stage Small-cell Lung Cancer | COMPLETED | PHASE1, PHASE2 | 2013-11-05 | 2017-05-04 | 2016-08 |
| NCT01881789 | Oprozomib and Dexamethasone,in Combination With Lenalidomide or Oral Cyclophosphamide to Treat Newly Diagnosed Multiple Myeloma | TERMINATED | PHASE1, PHASE2 | 2013-10-28 | 2019-09-23 | 2019-09-23 |
| NCT01970488 | Study to Compare Efficacy and Safety of ABP 501 and Adalimumab (HUMIRA®) in Adults With Moderate to Severe Plaque Psoriasis | COMPLETED | PHASE3 | 2013-10-18 | 2015-03-18 | 2014-08-14 |
| NCT01949545 | Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Advanced Malignancies and Hepatic Impairment | COMPLETED | PHASE1 | 2013-10 | 2015-09 | 2015-08 |
| NCT01970475 | Efficacy and Safety Study of ABP 501 Compared to Adalimumab in Subjects With Moderate to Severe Rheumatoid Arthritis | COMPLETED | PHASE3 | 2013-10 | 2014-11 | 2014-11 |
| NCT01953328 | Study of Low-Density Lipoprotein Cholesterol (LDL-C) Reduction Using Evolocumab (AMG 145) in Japanese Patients With Advanced Cardiovascular Risk | COMPLETED | PHASE3 | 2013-10 | 2014-06 | 2014-06 |
| NCT01953341 | Single-Ascending Dose Study of AMG 333 in Healthy Subjects and Subjects With Migraines | COMPLETED | PHASE1 | 2013-10 | 2014-11 | 2014-09 |
| NCT01925768 | Safety and Efficacy Study of Apremilast to Treat Psoriatic Arthritis | COMPLETED | PHASE3 | 2013-09-04 | 2016-11-17 | 2015-02-25 |
| NCT01896232 | Head-to-Head Study of Etelcalcetide (AMG 416) and Cinacalcet | COMPLETED | PHASE3 | 2013-08-13 | 2015-01-08 | 2014-11-12 |
| NCT01932970 | Study to Assess the Impact on Calcium Levels When Hemodialysis Patients With Secondary Hyperparathyroidism (SHPT) Switch From Cinacalcet to Etelcalcetide | COMPLETED | PHASE3 | 2013-08-12 | 2017-02-14 | 2014-01-14 |
| NCT01952574 | Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Migraine Prevention | COMPLETED | PHASE2 | 2013-08-06 | 2019-11-12 | 2014-09-25 |
| NCT01980589 | A Multicenter, Open-label, Phase 1b Study of Carfilzomib, Cyclophosphamide and Dexamethasone in Newly Diagnosed Multiple Myeloma Subjects | COMPLETED | PHASE1 | 2013-08 | 2016-03 | 2016-03 |
| NCT01928368 | A First-in-Human, Double Blind, Single Dose Study in Healthy Subjects and Subjects With Mild Atopic Asthma. | COMPLETED | PHASE1 | 2013-08 | 2016-03 | 2016-03 |
| NCT01785875 | Extension Study of Etelcalcetide in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease (CKD) on Hemodialysis | COMPLETED | PHASE3 | 2013-07-31 | 2015-07-01 | 2015-07-01 |
| NCT01879319 | Study to Assess in Home Use of Evolocumab (AMG 145) Administration Using Either an Automated Mini-doser or a Prefilled Autoinjector/Pen | COMPLETED | PHASE3 | 2013-07-11 | | 2013-11-15 |
| NCT01988103 | Efficacy and Safety Study of Two Doses of Apremilast (CC-10004) In Japanese Patients With Moderate-To-Severe Plaque-Type Psoriasis | COMPLETED | PHASE2 | 2013-07-09 | 2015-12-15 | 2014-11-20 |
| NCT01818752 | Phase 3 Study of Carfilzomib, Melphalan, Prednisone vs Bortezomib, Melphalan, Prednisone in Newly Diagnosed Multiple Myeloma | COMPLETED | PHASE3 | 2013-07-08 | 2016-11-04 | 2016-07-15 |
| NCT01832727 | Phase 1b/2, Multicenter, Open-label Study of Oprozomib and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma | TERMINATED | PHASE1, PHASE2 | 2013-07-02 | 2019-06-25 | 2019-06-25 |
| NCT01868997 | Teprotumumab (RV 001) Treatment in Patients With Active Thyroid Eye Disease | COMPLETED | PHASE2 | 2013-07 | 2017-02-22 | 2016-03 |
| NCT01901185 | Study to Evaluate the Ability of Subjects With Rheumatoid Arthritis or Psoriatic Arthritis to Effectively Use a Reusable Autoinjector to Self-inject Etanercept | COMPLETED | PHASE3 | 2013-06-11 | 2013-12-30 | 2013-12-18 |
| NCT01875991 | Preference Between Two Autoinjectors in Patients With Rheumatoid Arthritis and Plaque Psoriasis Treated With Etanercept | COMPLETED | PHASE4 | 2013-06-05 | 2014-03-04 | 2014-03-04 |
| NCT01869686 | Study to Evaluate the Concentration of Denosumab in Seminal Fluid in Healthy Men After a Single Subcutaneous Dose | COMPLETED | PHASE1 | 2013-06 | 2013-09 | 2013-09 |
| NCT01902290 | Study of Efficacy and Safety of Brodalumab Compared With Placebo in Adults With Inadequately Controlled Asthma With High Bronchodilator Reversibility | TERMINATED | PHASE2 | 2013-05-22 | 2015-05-15 | 2015-05-15 |
| NCT01890109 | Study of Erenumab (AMG 334) in Women With Hot Flashes | COMPLETED | PHASE1 | 2013-05-13 | 2014-03-11 | 2014-03-11 |
| NCT01927757 | Evaluating Etanercept Use in Patients With Moderate to Severe Rheumatoid Arthritis Who Have Lost Response to Adalimumab | TERMINATED | PHASE4 | 2013-05-06 | 2015-06-11 | 2015-06-11 |
| NCT01901146 | Efficacy and Safety Study of ABP 980 Compared With Trastuzumab in Women With HER2-positive Early Breast Cancer | COMPLETED | PHASE3 | 2013-04-29 | 2017-01-27 | 2016-05-05 |
| NCT01854918 | Open-label Extension Study of Evolocumab (AMG 145) in Adults With Hyperlipidemia and Mixed Dyslipidemia | COMPLETED | PHASE3 | 2013-04-23 | 2018-05-31 | 2018-05-31 |
| NCT01833754 | Study of Romosozumab (AMG 785) Administered to Healthy Participants and Patients With Stage 4 Renal Impairment or Stage 5 Renal Impairment Requiring Hemodialysis | COMPLETED | PHASE1 | 2013-04-22 | 2014-02-19 | 2014-02-19 |
| NCT01813422 | GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound | COMPLETED | PHASE3 | 2013-04-18 | 2016-07-29 | 2016-07-12 |
| NCT01849497 | Study to Assess In-home Use of Evolocumab (AMG 145) Using a Prefilled Syringe or a Prefilled Autoinjector/Pen | COMPLETED | PHASE3 | 2013-04-18 | | 2013-09-02 |
| NCT01788046 | Efficacy and Safety of Etelcalcetide (AMG 416) in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease (CKD) on Hemodialysis | COMPLETED | PHASE3 | 2013-03-12 | 2014-05-09 | 2014-04-14 |
| NCT01785849 | Efficacy and Safety of Etelcalcetide (AMG 416) in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease on Hemodialysis | COMPLETED | PHASE3 | 2013-03-12 | 2014-06-12 | 2014-05-22 |
| NCT01856881 | Multiple Ascending Dose Study in Subjects With Type 2 Diabetes | TERMINATED | PHASE1 | 2013-03 | 2015-03 | 2014-11 |
| NCT01764633 | Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk | COMPLETED | PHASE3 | 2013-02-08 | 2016-11-11 | 2016-11-11 |
| NCT01740297 | Ipilimumab With or Without Talimogene Laherparepvec in Unresected Melanoma | COMPLETED | PHASE1, PHASE2 | 2013-02-07 | 2021-03-09 | 2016-08-23 |
| NCT01763918 | Reduction of LDL-C With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study-2 | COMPLETED | PHASE3 | 2013-02-07 | 2013-12-19 | 2013-11-27 |
| NCT01733316 | Open-Label, Safety and Superior Effectiveness Study of Cysteamine Bitartrate Delayed-Release Capsules (RP103) in Cystinosis | COMPLETED | PHASE3 | 2013-01-31 | 2017-07-10 | 2015-02 |
| NCT01796301 | An Open-label Study to Evaluate the Effect of Treatment With Romosozumab or Teriparatide in Postmenopausal Women | COMPLETED | PHASE3 | 2013-01-31 | 2015-05-14 | 2015-05-14 |
| NCT01763905 | Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2 | COMPLETED | PHASE3 | 2013-01-24 | 2013-11-19 | 2013-11-19 |
| NCT01763827 | Monoclonal Antibody Against PCSK9 to Reduce Elevated LDL-C in Subjects Currently Not Receiving Drug Therapy for Easing Lipid Levels-2 | COMPLETED | PHASE3 | 2013-01-21 | 2013-10-29 | 2013-10-10 |
| NCT01752907 | Effect of Patient Education on Reported Bone Pain in Breast Cancer Patients Receiving Chemotherapy and Pegfilgrastim | COMPLETED | PHASE2 | 2013-01-17 | 2014-12-15 | 2014-12-15 |
| NCT01763866 | LDL-C Assessment With PCSK9 Monoclonal Antibody Inhibition Combined With Statin Therapy-2 | COMPLETED | PHASE3 | 2013-01-15 | 2013-12-04 | 2013-11-12 |
| NCT01744782 | Safety/Effectiveness Study of Cysteamine Bitartrate Delayed-release Capsules (RP103) in Cysteamine Treatment Naive Patients With Cystinosis | COMPLETED | PHASE3 | 2012-12-20 | 2016-12-13 | 2016-12-13 |
| NCT01696396 | Abrilumab (AMG 181) in Adults With Moderate to Severe Crohn's Disease | COMPLETED | PHASE2 | 2012-12-04 | 2018-04-10 | 2014-12-26 |
| NCT01694485 | Abrilumab (AMG 181) in Adults With Moderate to Severe Ulcerative Colitis | COMPLETED | PHASE2 | 2012-11-16 | 2018-04-10 | 2015-07-13 |
| NCT01723514 | Ascending Multiple-Doses of Erenumab (AMG 334) in Healthy Adults and in Migraine Patients | COMPLETED | PHASE1 | 2012-11-14 | 2014-07-10 | 2014-07-10 |
| NCT01732770 | Safety and Efficacy Study to Evaluate Denosumab Compared With Zoledronic Acid in Postmenopausal Women With Osteoporosis | COMPLETED | PHASE4 | 2012-11-07 | 2015-01-07 | 2015-01-07 |
| NCT01712009 | NOLAN: Naproxen or Loratadine and Neulasta | COMPLETED | PHASE2 | 2012-11-01 | 2015-03-18 | 2015-03-18 |
| NCT01791374 | Phase 1/1b Study of Rilotumumab in Japanese Subjects With Advanced Solid Tumors or Advanced or Metastatic Gastric or GEJ | COMPLETED | PHASE1 | 2012-11 | 2015-03 | 2013-08 |
| NCT01755442 | Investigate Effect of AMG 151 on 24-hour Ambulatory Blood Pressure & Glucose Levels in Type 2 Diabetes Mellitus Subjects | TERMINATED | PHASE1 | 2012-11 | 2013-01 | 2013-01 |
| NCT01992159 | Efficacy, Safety and Tolerability of Romosozumab in the Treatment of Japanese Women With Postmenopausal Osteoporosis | COMPLETED | PHASE2 | 2012-10-12 | 2015-06-17 | 2014-10-09 |
| NCT01690299 | Phase 3b Safety and Efficacy Study of Apremilast to Treat Moderate to Severe Plaque-plaque Psoriasis | COMPLETED | PHASE3 | 2012-10-01 | 2016-04-04 | 2014-07-03 |
| NCT01697072 | First-Line Treatment for Locally Advanced or Metastatic Mesenchymal Epithelial Transition Factor (MET) - Positive Gastric, Lower Esophageal, or Gastroesophageal Junction (GEJ) Adenocarcinoma | TERMINATED | PHASE3 | 2012-10 | 2015-08 | 2014-11 |
| NCT01695876 | A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), Food Effect of AMG 357 in Healthy Subjects | COMPLETED | PHASE1 | 2012-10 | 2014-10 | 2014-09 |
| NCT01737879 | Evaluation of the Conversion From Peginesatide to Epoetin Alfa in Patients Receiving Hemodialysis | TERMINATED | PHASE4 | 2012-10 | 2013-07 | 2013-03 |
| NCT01666977 | Phase 1b/2 Trial of AMG386 With Pemetrexed and Carboplatin in Non-Small Cell Lung Cancer | COMPLETED | PHASE1, PHASE2 | 2012-08 | 2015-11 | 2015-11 |
| NCT01652872 | Strategies Using Darbepoetin Alfa to Avoid Transfusions in Chronic Kidney Disease | COMPLETED | PHASE3 | 2012-07-30 | 2017-10-19 | 2017-10-19 |
| NCT01652703 | A Study to Evaluate Tolerability and Efficacy of Evolocumab (AMG 145) in Japanese Subjects | COMPLETED | PHASE2 | 2012-07-10 | | 2013-05-14 |
| NCT01677858 | A Study of Weekly Carfilzomib in Combination With Dexamethasone for Progressive Multiple Myeloma | COMPLETED | PHASE1, PHASE2 | 2012-07-04 | 2018-10-31 | 2016-07-22 |
| NCT01741792 | Clinical Study With Blinatumomab in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL) | COMPLETED | PHASE2 | 2012-07 | 2015-09 | 2014-07 |
| NCT01992341 | AMG 386 Drug-Drug Interaction Study With Paclitaxel | COMPLETED | PHASE1 | 2012-07 | 2014-09 | 2013-08 |
| NCT01439867 | Safety & Tolerability of Cinacalcet in Pediatric Patients With Chronic Kidney Disease and Secondary Hyperparathyroidism | TERMINATED | PHASE2 | 2012-06-22 | 2016-06-03 | 2016-06-03 |
| NCT01568866 | Phase 3 Study With Carfilzomib and Dexamethasone Versus Bortezomib and Dexamethasone for Relapsed Multiple Myeloma Patients | COMPLETED | PHASE3 | 2012-06-20 | 2018-02-05 | 2014-11-10 |
| NCT01624142 | Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders | COMPLETED | PHASE2, PHASE3 | 2012-06-01 | 2018-05-11 | 2018-05-11 |
| NCT01683695 | Safety Study of AMG 557 in Subjects With Lupus Arthritis | COMPLETED | PHASE1 | 2012-06 | 2016-03 | 2016-03 |
| NCT01345019 | Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma | COMPLETED | PHASE3 | 2012-05-17 | 2019-03-29 | 2016-07-19 |
| NCT01631214 | Study to Determine the Efficacy and Safety of Romosozumab in the Treatment of Postmenopausal Women With Osteoporosis | COMPLETED | PHASE3 | 2012-05-04 | 2017-06-29 | 2017-02-27 |
| NCT01583374 | Study of Apremilast to Treat Subjects With Active Ankylosing Spondylitis | COMPLETED | PHASE3 | 2012-05-02 | 2018-10-25 | 2014-02-24 |
| NCT01568216 | 20101299: Study to Evaluate the Effect of AMG 747 on Schizophrenia Negative Symptoms | TERMINATED | PHASE2 | 2012-05 | 2013-06 | 2013-06 |
| NCT01568229 | 20110165: Study to Evaluate the Effect of AMG 747 on Schizophrenia Negative Symptoms (Study 165) | TERMINATED | PHASE2 | 2012-05 | 2013-08 | 2013-06 |
| NCT01588496 | Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities | COMPLETED | PHASE2, PHASE3 | 2012-04-05 | 2014-01-31 | 2014-01-31 |
| NCT01544114 | A Safety Study of VIMOVO in Adolescents With Juvenile Idiopathic Arthritis (JIA) | COMPLETED | PHASE4 | 2012-04 | 2015-02 | 2015-02 |
| NCT01563185 | Open-label Safety and Pharmacokinetic Study of DUEXIS® (Ibuprofen and Famotidine) Tablets in Juvenile Idiopathic Arthritis | COMPLETED | PHASE4 | 2012-04 | 2015-03 | 2015-03 |
| NCT01588509 | Transition From Alendronate to Romosozumab (AMG 785) | COMPLETED | PHASE1 | 2012-03-30 | 2012-11-21 | 2012-11-21 |
| NCT01575873 | Efficacy and Safety of Denosumab Compared With Risedronate in Individuals Taking Glucocorticoids | COMPLETED | PHASE3 | 2012-03-28 | 2017-06-29 | 2016-06-21 |
| NCT01575834 | Efficacy and Safety of Romosozumab Treatment in Postmenopausal Women With Osteoporosis | COMPLETED | PHASE3 | 2012-03-15 | 2016-12-28 | 2015-12-14 |
| NCT01688739 | Ascending Single Doses of Erenumab (AMG 334) in Healthy Adults and Migraine Patients | COMPLETED | PHASE1 | 2012-03-13 | 2013-03-27 | 2013-03-27 |
| NCT01561963 | A Drug-Drug Interaction Study to Evaluate the Effect of Rifampin on the Pharmacokinetics of Apremilast | COMPLETED | PHASE1 | 2012-02-01 | 2012-04-01 | 2012-04-01 |
| NCT01634178 | Effect of Food on the Pharmacokinetics of Apremilast (CC-10004) in Healthy Adults | COMPLETED | PHASE1 | 2012-02-01 | 2012-03-01 | 2012-03-01 |
| NCT01634191 | Effects of Age and Sex on the Pharmacokinetics of Apremilast in Healthy Adults | COMPLETED | PHASE1 | 2012-02-01 | 2012-04-01 | 2012-03-01 |
| NCT01543204 | Etanercept Treatment in Patients With Moderate to Severe Plaque Psoriasis Who Lost Response to Adalimumab | TERMINATED | PHASE4 | 2012-02-01 | 2015-05-29 | 2015-05-29 |
| NCT01475006 | AMG 595 First-in-Human in Recurrent Gliomas | COMPLETED | PHASE1 | 2012-02 | 2016-04 | 2016-04 |
| NCT01516879 | Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study | COMPLETED | PHASE3 | 2012-01-05 | 2013-10-14 | 2013-10-14 |
| NCT01444417 | Safety and Efficacy Study of Romiplostim to Treat Immune Thrombocytopenia (ITP) in Pediatric Patients | COMPLETED | PHASE3 | 2012-01 | 2015-02 | 2015-02 |
| NCT01493505 | TRINOVA-3: A Study of AMG 386 or AMG 386 Placebo in Combination With Paclitaxel and Carboplatin to Treat Ovarian Cancer | TERMINATED | PHASE3 | 2012-01 | 2016-12 | 2016-03 |
| NCT01471782 | Clinical Study With Blinatumomab in Pediatric and Adolescent Patients With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia | COMPLETED | PHASE1, PHASE2 | 2012-01 | 2016-05 | 2014-08 |
| NCT01497821 | AMG 172 First in Human Study in Patients With Kidney Cancer | COMPLETED | PHASE1 | 2012-01 | 2015-01 | 2014-11 |
| NCT01362140 | Darbepoetin Alfa in Patients With Anemic Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) | COMPLETED | PHASE3 | 2011-12-21 | 2017-09-14 | 2015-02-11 |
| NCT01466179 | Clinical Study With Blinatumomab in Patients With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (ALL) | COMPLETED | PHASE2 | 2011-12 | 2017-01 | 2013-10 |
| NCT01514981 | AMG 761 in Adults With Asthma | TERMINATED | PHASE1 | 2011-12 | 2014-02 | 2014-01 |
| NCT01419717 | Open-Label Access Protocol of Denosumab for Subjects With Advanced Cancer | COMPLETED | PHASE3 | 2011-11-22 | 2018-08-10 | 2018-08-10 |
| NCT01412957 | Comparison of Survival Benefit of Panitumumab With Supportive Care to Best Supportive Care Alone in Patients With Metastatic Colorectal Cancer | COMPLETED | PHASE3 | 2011-11 | 2016-11 | 2014-06 |
| NCT01464931 | Multiple Dose Study to Evaluate the Safety of Multiple Doses of Denosumab 120 mg in Adults With Severe Chronic Kidney Disease (CKD) and CKD on Dialysis | COMPLETED | PHASE1 | 2011-11 | 2013-03 | 2013-01 |
| NCT01493518 | Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of AMG 557 in Adults With Psoriasis | TERMINATED | PHASE1 | 2011-11 | 2013-06 | 2013-05 |
| NCT01492465 | Single Ascending Dose Trial in Patients With Type 2 Diabetes | TERMINATED | PHASE1 | 2011-11 | 2012-10 | 2012-07 |
| NCT01405963 | Double-blind, Multiple Dose Study of Tezepelumab (AMG 157) in Adults With Mild Atopic Asthma | COMPLETED | PHASE1 | 2011-10-31 | 2013-04-05 | 2013-04-05 |
| NCT01416428 | Open-label Study of the Safety and Activity of Oprozomib in Patients With Hematologic Malignancies | TERMINATED | PHASE1, PHASE2 | 2011-10-15 | 2019-08-12 | 2016-08-08 |
| NCT01439880 | Open Label Study of Long Term Evaluation Against LDL-C Trial | COMPLETED | PHASE2 | 2011-10-07 | 2018-06-20 | 2018-06-20 |
| NCT01380756 | Study Evaluating Orally Administered AMG 900 in Adult Subjects With Acute Myeloid Leukemia | COMPLETED | PHASE1 | 2011-10-04 | 2014-09-04 | 2014-09-04 |
| NCT01447147 | A Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects With Diabetic Nephropathy | COMPLETED | PHASE2 | 2011-10 | 2014-12 | 2014-08 |
| NCT01389895 | Safety Study of AMG 557 in Subjects With Subacute Cutaneous Lupus Erythematosus | TERMINATED | PHASE1 | 2011-10 | 2013-03 | 2013-03 |
| NCT01331941 | A Pharmacokinetic Study of AMG 386 in Cancer Subjects With Normal and Impaired Renal Function | COMPLETED | PHASE1 | 2011-09-19 | | 2013-02-26 |
| NCT01363388 | A Study to Evaluate the Safety and Efficacy of CCX168 in Subjects With ANCA-Associated Vasculitis | COMPLETED | PHASE2 | 2011-09 | 2016-01 | 2015-10 |
| NCT01440257 | A Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and Albuminuria | COMPLETED | PHASE2 | 2011-09 | 2013-09 | 2013-02 |
| NCT01464437 | AMG 151 Amgen Protocol Number 20100761 | COMPLETED | PHASE2 | 2011-09 | 2012-12 | 2012-10 |
| NCT01568203 | First-in-Human Study to Evaluate AMG 579 in Healthy Subjects and Patients With Stable Schizophrenia | TERMINATED | PHASE1 | 2011-09 | 2012-06 | 2012-06 |
| NCT01375751 | Reduction of Low-Density Lipoprotein Cholesterol (LDL-C) With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study | COMPLETED | PHASE2 | 2011-08-02 | 2012-05-16 | 2012-05-16 |
| NCT01510951 | Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of AMG 811 in Subjects With Psoriasis | COMPLETED | PHASE1 | 2011-08 | 2012-10 | 2012-10 |
| NCT01375764 | Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects | COMPLETED | PHASE2 | 2011-07-28 | 2012-05-08 | 2012-05-08 |
| NCT01375777 | Monoclonal Antibody Against PCSK9 to Reduce Elevated Low-density Lipoprotein Cholesterol (LDL-C) in Adults Currently Not Receiving Drug Therapy for Easing Lipid Levels | COMPLETED | PHASE2 | 2011-07-06 | 2012-03-02 | 2012-03-02 |
| NCT01347073 | Study of the Safety, Pharmacokinetics and Efficacy of HPN-100, in Pediatric Subjects With Urea Cycle Disorders (UCDs) | COMPLETED | PHASE3 | 2011-07 | 2013-03 | 2013-02 |
| NCT01380730 | LAPLACE-TIMI 57: Low-density Lipoprotein Cholesterol (LDL-C) Assessment With PCSK9 monoclonaL Antibody Inhibition Combined With Statin thErapy | COMPLETED | PHASE2 | 2011-07-01 | 2012-04-05 | 2012-04-05 |
| NCT01277510 | Pediatric Chronic Kidney Disease Safety and Efficacy | TERMINATED | PHASE3 | 2011-06-28 | | 2014-04-30 |
| NCT01395485 | Safety, Tolerability, and Pharmacokinetics of AMG 827 in Adolescents With Asthma | WITHDRAWN | PHASE1 | 2011-06 | 2012-06 | 2012-06 |
| NCT01281254 | AMG 386 (Trebananib) in Ovarian Cancer (TRINOVA-2) | TERMINATED | PHASE3 | 2011-04-18 | 2017-04-19 | 2014-08-29 |
| NCT01313221 | Efficacy and Safety of Etanercept 50 mg Once Weekly Plus As Needed Topical Agent in Moderate to Severe Plaque Psoriasis | COMPLETED | PHASE3 | 2011-04 | 2013-05 | 2012-12 |
| NCT01300026 | AMG 319 Lymphoid Malignancy FIH | COMPLETED | PHASE1 | 2011-04 | 2016-12 | 2013-10 |
| NCT01327612 | Open Label Extension Study of Conatumumab and Ganitumab (AMG 479) | COMPLETED | PHASE2 | 2011-03-03 | 2020-02-05 | 2020-02-05 |
| NCT01294397 | Effects of Denosumab on the Pharmacokinetics of Etanercept | TERMINATED | PHASE1 | 2011-03 | 2016-01 | 2016-01 |
| NCT01313208 | Moderate Rheumatoid Arthritis (RA) With Etanercept (Enbrel) | COMPLETED | PHASE4 | 2011-03 | 2013-05 | 2013-02 |
| NCT01199302 | Long-term Safety Study of Brodalumab in Adults With Crohn's Disease | TERMINATED | PHASE2 | 2011-02-02 | 2011-10-18 | 2011-10-18 |
| NCT01290042 | Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 181. | COMPLETED | PHASE1 | 2011-02 | 2014-05 | 2014-04 |
| NCT01290029 | Study to Evaluate Cinacalcet in Children With Chronic Kidney Disease | COMPLETED | PHASE1 | 2011-01-25 | 2015-09-23 | 2015-09-23 |
| NCT01270347 | Trial of Aeroquin Versus Tobramycin Inhalation Solution (TIS) in Cystic Fibrosis (CF) Patients | COMPLETED | PHASE3 | 2011-01 | 2013-06 | 2012-10 |
| NCT01824342 | Denosumab for Prolonging Bone Metastasis-Free Survival in Men With Hormone-Refractory Prostate Cancer | COMPLETED | PHASE3 | 2011-01 | 2014-02 | 2014-02 |
| NCT01307423 | Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis (PsA) | COMPLETED | PHASE3 | 2010-12-09 | 2017-08-16 | 2013-02-21 |
| NCT01285310 | Study of Apremilast to Evaluate the Safety and Effectiveness for Patients With Rheumatoid Arthritis | TERMINATED | PHASE2 | 2010-12-09 | 2012-09-10 | 2012-02-21 |
| NCT01253707 | A Study of AMG 337 in Subjects With Advanced Solid Tumors | COMPLETED | PHASE1 | 2010-12-08 | 2016-12-13 | 2015-10-01 |
| NCT01143038 | Interventional Study in Adults With Immune Thrombocytopenia Purpura (ITP) Receiving Romiplostim | COMPLETED | PHASE2 | 2010-11-30 | 2013-12-26 | 2013-09-20 |
| NCT01232283 | Study to Evaluate Safety and Effectiveness of Oral Apremilast (CC-10004) in Patients With Moderate to Severe Plaque Psoriasis. | COMPLETED | PHASE3 | 2010-11-22 | 2016-11-30 | 2012-03-15 |
| NCT01150890 | Brodalumab (AMG 827) in Adults With Moderate to Severe Crohn's Disease | TERMINATED | PHASE2 | 2010-11-09 | 2011-10-15 | 2011-10-15 |
| NCT01180634 | MP-376 (Aeroquin™, Levofloxacin for Inhalation) in Patients With Cystic Fibrosis | COMPLETED | PHASE3 | 2010-11-04 | 2012-05-07 | 2012-05-07 |
| NCT01207388 | Confirmatory Phase II Study of Blinatumomab (MT103) in Patients With Minimal Residual Disease of B-precursor Acute Lymphoblastic Leukemia (ALL) | COMPLETED | PHASE2 | 2010-11 | 2019-01-07 | 2014-02 |
| NCT01204749 | TRINOVA-1: A Study of AMG 386 or Placebo, in Combination With Weekly Paclitaxel Chemotherapy, as Treatment for Ovarian Cancer, Primary Peritoneal Cancer and Fallopian Tube Cancer | COMPLETED | PHASE3 | 2010-11 | 2016-12 | 2013-03 |
| NCT01253681 | Study of AMG 386 in Combination With Paclitaxel and Carboplatin in Subjects With Ovarian Cancer | COMPLETED | PHASE1 | 2010-11 | 2015-01 | 2012-10 |
| NCT01221727 | The Effects of Denosumab on the Pharmacokinetics (PK) of Midazolam | COMPLETED | PHASE1 | 2010-11 | 2011-07 | 2011-07 |
| NCT01257737 | To Evaluate the Safety of Long-term Use of HPN-100 in the Management of Urea Cycle Disorders (UCDs) | COMPLETED | PHASE4 | 2010-10-04 | 2017-02-16 | 2017-02-16 |
| NCT01199289 | A Study to Evaluate the Dosing of AMG 827 for Subjects With Inadequately Controlled Asthma | COMPLETED | PHASE2 | 2010-10-04 | 2011-12-21 | 2011-12-21 |
| NCT01300208 | To Evaluate the Preliminary Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of CC-11050 in Subjects With Discoid Lupus Erythematosus and Subacute Cutaneous Lupus Erythematosus | COMPLETED | PHASE2 | 2010-10-01 | 2013-03-01 | 2013-01-01 |
| NCT01181531 | Compare the Efficacy of Cinacalcet vs Traditional Vitamin D for Secondary Hyperparathyroidism (SHPT) Among Subjects Undergoing Hemodialysis | COMPLETED | PHASE4 | 2010-10-01 | 2012-08-14 | 2012-07-17 |
| NCT01209286 | Study of the BiTE® Blinatumomab (MT103) in Adult Patients With Relapsed/Refractory B-Precursor Acute Lymphoblastic Leukemia (ALL) | COMPLETED | PHASE2 | 2010-10 | 2016-10 | 2012-03 |
| NCT01212770 | PALACE 3: Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis | COMPLETED | PHASE3 | 2010-09-30 | 2017-02-09 | 2012-08-21 |
| NCT01212757 | PALACE 2: Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis | COMPLETED | PHASE3 | 2010-09-27 | 2017-01-25 | 2012-07-26 |
| NCT01194219 | Study to Evaluate Safety and Effectiveness of Oral Apremilast (CC-10004) in Patients With Moderate to Severe Plaque Psoriasis | COMPLETED | PHASE3 | 2010-09-09 | 2016-11-22 | 2012-02-23 |
| NCT01242917 | A Study to Evaluate the Safety and Efficacy of CCX354-C in Subjects With Rheumatoid Arthritis Partially Responsive to Methotrexate Therapy | COMPLETED | PHASE2 | 2010-09 | 2011-07 | 2011-07 |
| NCT01302392 | A Study of Carfilzomib vs Best Supportive Care in Subjects With Relapsed and Refractory Multiple Myeloma | COMPLETED | PHASE3 | 2010-09 | 2015-09 | 2014-07 |
| NCT01235442 | Evaluate Efficacy, and Safety of Topical Therapy and Etanercept in Subjects With Moderate to Severe Plaque Psoriasis | COMPLETED | PHASE3 | 2010-09 | 2011-12 | 2011-10 |
| NCT01197378 | Long-Term Safety Follow-up Study of Cysteamine Bitartrate Delayed-release Capsules (RP103) | COMPLETED | PHASE3 | 2010-08-27 | 2017-06-26 | 2017-06-26 |
| NCT01164917 | Safety Study of AMG 811 in Subjects With Discoid Lupus Erythematosus | TERMINATED | PHASE1 | 2010-08 | 2013-03 | 2012-09 |
| NCT01080391 | Study Comparing Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects With Relapsed Multiple Myeloma | COMPLETED | PHASE3 | 2010-07-14 | 2017-12-05 | 2014-06-16 |
| NCT01164904 | Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 181 in Healthy Subjects and Subjects With Mild to Moderate Ulcerative Colitis | TERMINATED | PHASE1 | 2010-07 | 2013-03 | 2013-01 |
| NCT01081678 | Study To Assess FRacTure Healing With SclerosTin Antibody - Hip | COMPLETED | PHASE2 | 2010-06-20 | 2013-05-10 | 2012-06-30 |
| NCT01059448 | Safety and Efficacy of AMG 827 in Subjects With RA | TERMINATED | PHASE2 | 2010-06-03 | 2011-04-05 | 2011-04-05 |
| NCT01077154 | Study of Denosumab as Adjuvant Treatment for Women With High Risk Early Breast Cancer Receiving Neoadjuvant or Adjuvant Therapy (D-CARE) | TERMINATED | PHASE3 | 2010-06-02 | 2018-03-26 | 2017-08-31 |
| NCT01172938 | Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis | COMPLETED | PHASE3 | 2010-06-02 | 2016-10-27 | 2012-04-27 |
| NCT01000961 | Phase 3 Study of Cysteamine Bitartrate Delayed-release (RP103) Compared to Cystagon® in Patients With Cystinosis | COMPLETED | PHASE3 | 2010-06 | 2011-08 | 2011-06 |
| NCT01133522 | Ascending Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Evolocumab (AMG 145) in Adults With Hyperlipidemia on Stable Doses of a Statin | COMPLETED | PHASE1 | 2010-06-01 | 2011-09-14 | 2011-09-14 |
| NCT01101048 | An Ascending Multiple Dose Study Evaluating AMG 167 in Healthy Men and Postmenopausal Women With Low Bone Mineral Density | COMPLETED | PHASE1 | 2010-06 | 2012-02 | 2012-02 |
| NCT01137552 | A Phase 1 Dose Escalation Study of AMG 780 in Adult Subjects With Advanced Solid Tumors | TERMINATED | PHASE1 | 2010-06 | 2014-04 | 2013-12 |
| NCT01137565 | Safety, Tolerability, and Pharcodynamics of AMG 853 in Adolescents With Asthma | COMPLETED | PHASE1 | 2010-06 | 2011-01 | 2011-01 |
| NCT01101061 | A Single-dose Study Evaluating Romosozumab (AMG 785) in Healthy Postmenopausal Japanese and Non-Japanese Women | COMPLETED | PHASE1 | 2010-05-03 | 2010-11-01 | 2010-11-01 |
| NCT01135680 | Double-Blind Randomized Crossover Trial to Access Electrocardiogram Effects of HPN-100 | COMPLETED | PHASE1 | 2010-05 | 2010-09 | 2010-09 |
| NCT01124279 | Single-dose, Pharmacokinetics of AMG 853 in Healthy Adult Subjects | COMPLETED | PHASE1 | 2010-05 | 2010-10 | 2010-08 |
| NCT00975104 | AMG 745 in Subjects With Age-associated Muscle Loss | WITHDRAWN | PHASE2 | 2010-04 | 2011-08 | 2011-05 |
| NCT01129349 | Phase 1 Study of Oprozomib Administered Orally in Patients With Advanced Refractory or Recurrent Solid Tumors | COMPLETED | PHASE1 | 2010-04 | 2013-03 | 2012-11 |
| NCT00975221 | Efficacy and Safety Study of Cinacalcet for the Treatment of Hypercalcemia in Patients With Primary Hyperparathyroidism Unable to Undergo Parathyroidectomy | COMPLETED | PHASE3 | 2010-03-10 | 2012-12-21 | 2012-07-12 |
| NCT00947544 | Study of the Safety and Tolerability of HPN-100 Compared to Sodium Phenylbutyrate in Children With Urea Cycle Disorders | COMPLETED | PHASE2 | 2010-03 | 2011-08 | 2011-08 |
| NCT01001377 | ASPECCT: A Study of Panitumumab Efficacy and Safety Compared to Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer | COMPLETED | PHASE3 | 2010-02-02 | 2017-03-07 | 2013-02-05 |
| NCT01028963 | A Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects With Type 2 Diabetes Mellitus | COMPLETED | PHASE2 | 2010-01 | 2010-11 | 2010-10 |
| NCT00950989 | Brodalumab (AMG 827) in Rheumatoid Arthritis (RA) Participants With Inadequate Response to Methotrexate | COMPLETED | PHASE2 | 2009-12-30 | 2011-02-11 | 2011-02-11 |
| NCT01071954 | A Study Evaluating the Safety and Efficacy of Long-term Dosing of Romiplostim in Thrombocytopenic Pediatric Patients With Immune (Idiopathic) Thrombocytopenia Purpura | COMPLETED | PHASE3 | 2009-12-30 | 2017-01-12 | 2017-01-12 |
| NCT05984251 | A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of CCX168 in Healthy Participants | COMPLETED | PHASE1 | 2009-12-21 | 2011-04-11 | 2010-09-19 |
| NCT00975000 | Treatment of Autonomous Hyperparathyroidism in Post Renal Transplant Recipients | COMPLETED | PHASE3 | 2009-12-03 | 2013-04-16 | 2012-09-13 |
| NCT01027728 | Study to Evaluate Safety and Efficacy of CCX 354-C in Subjects With Rheumatoid Arthritis | COMPLETED | PHASE1, PHASE2 | 2009-12 | 2010-07 | 2010-07 |
| NCT00999167 | A Study of Safety and Efficacy of HPN-100 in Subjects With Cirrhosis and Episodic Hepatic Encephalopathy | COMPLETED | PHASE2 | 2009-12 | 2012-04 | 2012-04 |
| NCT00925600 | Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss | COMPLETED | PHASE3 | 2009-11-30 | 2016-05-12 | 2016-05-12 |
| NCT00896454 | Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium | COMPLETED | PHASE2 | 2009-11-16 | 2013-08-21 | 2012-09-13 |
| NCT00911170 | PAVES: Pegfilgrastim Anti-vascular Endothelial Growth Factor (VEGF) Evaluation Study | COMPLETED | PHASE3 | 2009-11-03 | 2015-01-02 | 2012-09-17 |
| NCT00947297 | Study of the Safety of HPN (Hyperion)-100 for the Long-Term Treatment of Urea Cycle Disorders (Treat UCD) | COMPLETED | PHASE3 | 2009-11 | 2011-11 | 2011-09 |
| NCT01001208 | The Efficacy and Safety of Adding Methotrexate to Etanercept in Psoriasis | COMPLETED | PHASE3 | 2009-11 | 2011-02 | 2010-12 |
| NCT00992459 | Efficacy and Safety of HPN-100 for the Treatment of Adults With Urea Cycle Disorders | COMPLETED | PHASE3 | 2009-10 | 2010-09 | 2010-09 |
| NCT00980174 | Study to Compare the Efficacy and Safety of DenosumAb Versus Placebo in Males With Osteoporosis | COMPLETED | PHASE3 | 2009-10-01 | 2012-05-23 | 2011-06-21 |
| NCT01018550 | AMG 853 Phase 2 Study in Subjects With Inadequately Controlled Asthma | COMPLETED | PHASE2 | 2009-10 | 2011-03 | 2010-12 |
| NCT00972179 | Safety Study of Tezepelumab (AMG 157) in Healthy Adults | COMPLETED | PHASE1 | 2009-09-15 | 2011-01-09 | 2011-01-09 |
| NCT00907296 | Study of Romosozumab (AMG 785) in Tibial Diaphyseal Fractures Status Post Intramedullary Nailing | COMPLETED | PHASE2 | 2009-09-02 | 2013-05-10 | 2012-03-06 |
| NCT00984815 | Safety Study of HZT-501 in Patients Who Require Long-Term Daily Non-steroidal Anti-inflammatory Drug Treatment | COMPLETED | PHASE3 | 2009-09 | 2011-07 | 2011-07 |
| NCT00919711 | Study to Evaluate the Safety and Efficacy of Denosumab and Actonel® in Post Menopausal Women Transitioned From Alendronate Therapy | COMPLETED | PHASE3 | 2009-09-01 | 2012-03-05 | 2011-12-21 |
| NCT00950950 | A Study to Evaluate the Effect of Romosozumab (AMG 785) on Bone Quality of the Forearm in Postmenopausal Women With Low Bone Mass | COMPLETED | PHASE1 | 2009-08-18 | 2010-08-19 | 2010-08-19 |
| NCT00907478 | Study on Bone Marrow Morphology in Adults Receiving Romiplostim for Treatment of Thrombocytopenia Associated With Immune Thrombocytopenia Purpura (ITP) | COMPLETED | PHASE4 | 2009-08-11 | 2014-01-14 | 2014-01-09 |
| NCT00858377 | A Phase 1 First-in-Human Study Evaluating AMG 900 in Advanced Solid Tumors | COMPLETED | PHASE1 | 2009-08-10 | 2019-04-03 | 2014-12-31 |
| NCT00866359 | A Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in the Treatment of Behçet Disease | COMPLETED | PHASE2 | 2009-08-01 | 2012-05-01 | 2012-05-01 |
| NCT00872014 | A Study of the Effectiveness and Safety of AMG 386 and Sorafenib to Treat Advanced or Inoperable Hepatocellular Cancer | COMPLETED | PHASE2 | 2009-08 | 2015-06 | 2011-10 |
| NCT00858364 | Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy | TERMINATED | PHASE3 | 2009-07-17 | 2017-06-07 | 2017-06-07 |
| NCT00890981 | A High-resolution Peripheral Quantitative Computed Tomography Study in Postmenopausal Women Previously Treated With Denosumab | COMPLETED | PHASE3 | 2009-07 | 2010-08 | 2010-06 |
| NCT00950911 | Open Label Extension to SRE Studies in United Kingdom and Czech Republic Only | COMPLETED | PHASE3 | 2009-07 | 2012-04 | 2012-02 |
| NCT00936897 | A Study to Evaluate the Safety and Efficacy of Denosumab and Ibandronate in Postmenopausal Women Sub-Optimally Treated With Daily or Weekly Bisphosphonates | COMPLETED | PHASE3 | 2009-07 | 2012-01 | 2011-11 |
| NCT00896532 | Romosozumab (AMG 785) in Postmenopausal Women With Low Bone Mineral Density | COMPLETED | PHASE2 | 2009-06-03 | 2016-02-18 | 2011-02-21 |
| NCT00925587 | Evaluation of Monthly Darbepoetin Alfa Dosing for Correction of Anemia in Non-dialysis Chronic Kidney Disease | COMPLETED | PHASE3 | 2009-06 | 2012-05 | 2012-04 |
| NCT00887965 | A Transiliac Crest Bone Histology and Histomorphometry Study in Postmenopausal Women With Low Bone Mass or Osteoporosis Previously Treated With Denosumab | COMPLETED | PHASE2 | 2009-06 | 2010-08 | 2010-06 |
| NCT00853372 | AMG 386 Phase 2 Open-Label Renal Cell Carcinoma (RCC) Study 1st Line or After Cytokine Failure in Combination With Sunitinib | COMPLETED | PHASE2 | 2009-05-28 | 2019-06-25 | 2011-08-08 |
| NCT00872729 | Pilot Study of Safety, Tolerability, Pharmacokinetics/Pharmacodynamics of RP103 Compared to Cystagon® in Patients With Cystinosis | COMPLETED | PHASE1, PHASE2 | 2009-05 | 2009-10 | 2009-10 |
| NCT01386866 | Single Dose Study of [14C]-Labelled AMG 706 in Patients With Advanced Solid Tumors | COMPLETED | PHASE1 | 2009-05 | 2010-12 | 2010-11 |
| NCT00902356 | A First-in-human Study Evaluating AMG 167 in Healthy Men and Postmenopausal Women | COMPLETED | PHASE1 | 2009-05 | 2009-11 | 2009-11 |
| NCT00819780 | PEAK: Panitumumab Plus mFOLFOX6 vs. Bevacizumab Plus mFOLFOX6 for First Line Treatment of Metastatic Colorectal Cancer (mCRC) Patients With Wild-Type Kirsten Rat Sarcoma-2 Virus (KRAS) Tumors | COMPLETED | PHASE2 | 2009-04-24 | 2016-07-07 | 2012-05-30 |
| NCT00884312 | A Study of Extended Carfilzomib Therapy for Patients Previously Enrolled in Carfilzomib Treatment Protocols | COMPLETED | PHASE2 | 2009-04-09 | 2017-05-17 | 2017-05-17 |
| NCT00840333 | "Safety, Tolerability and Pharmacokinetics of MP-376 Administered for 14 Days to Stable Pediatric (CF) Patients" | COMPLETED | PHASE1 | 2009-04 | 2009-12 | 2009-12 |
| NCT00807859 | Safety Study of AMG 386 to Treat HER2-positive Locally Recurrent or Metastatic Breast Cancer | COMPLETED | PHASE1 | 2009-03-09 | 2015-10-19 | 2014-02-27 |
| NCT00818948 | Safety Study of AMG 811 in Subjects With Systemic Lupus Erythematosus With and Without Glomerulonephritis | COMPLETED | PHASE1 | 2009-03 | 2014-08 | 2014-06 |
| NCT00866944 | Study of Adecatumumab Relative to FOLFOX After R0 Resection of Colorectal Liver Metastases | COMPLETED | PHASE2 | 2009-03 | 2011-11 | 2011-07 |
| NCT00803712 | 20070360 Incident Dialysis | COMPLETED | PHASE4 | 2009-02-01 | 2011-07-05 | 2010-12-09 |
| NCT00838201 | Extension Study to Evaluate Long Term Safety of Denosumab in Subjects Undergoing ADT for Non-Metastatic Prostate Cancer | COMPLETED | PHASE3 | 2009-02-01 | 2012-05-03 | 2012-05-03 |
| NCT00719550 | AMG 102 Plus ECX for Unresectable Locally Advanced or Metastatic Gastric or Esophagogastric Junction Cancer | COMPLETED | PHASE1, PHASE2 | 2009-02 | 2013-06 | 2010-11 |
| NCT00770536 | AMG386 Comb w. Either Pegylated Liposomal Doxorubicin or Topotecan Subjects w. Advanced Recurrent Epithelial Ovarian CR | COMPLETED | PHASE1 | 2009-01 | 2015-06 | 2012-01 |
| NCT00813384 | A Phase 1 Study of AMG 208 in Subjects With Advanced Solid Tumors | COMPLETED | PHASE1 | 2008-12 | 2014-12 | 2013-02 |
| NCT00774943 | A Study of AMG 557 in Adults With Systemic Lupus Erythematosus | COMPLETED | PHASE1 | 2008-12 | 2012-05 | 2012-05 |
| NCT00721734 | Study of the Safety and Pharmacokinetics of Carfilzomib in Patients With Relapsed and Refractory Multiple Myeloma and Varying Degrees of Renal Function | COMPLETED | PHASE2 | 2008-11 | 2012-11 | 2012-11 |
| NCT00752570 | A Phase 2, Randomized, Double Blind, Placebo Controlled Study of AMG 386 in Combination With FOLFIRI in Subjects With Previously Treated Metastatic Colorectal Carcinoma | COMPLETED | PHASE2 | 2008-11 | 2012-06 | 2010-09 |
| NCT00770848 | AMG 102 in Combination With Mitoxantrone and Prednisone in Subjects With Previously Treated Castrate Resistant Prostate Cancer | COMPLETED | PHASE1, PHASE2 | 2008-11 | 2012-04 | 2011-01 |
| NCT00771030 | Study to Evaluate the Safety, PK, PD and Efficacy of AMG 827 in Adults With Rheumatoid Arthritis | COMPLETED | PHASE1, PHASE2 | 2008-10-27 | 2010-05-25 | 2010-05-25 |
| NCT00756444 | A Randomized Phase 2 Pharmacokinetic Trial of Chemotherapy With or Without Panitumumab in Patients With Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head and Neck | COMPLETED | PHASE2 | 2008-10-21 | 2012-03-30 | 2012-03-30 |
| NCT00739648 | A Phase 2 Study of MP-376 to Prevent Acute Exacerbations in Chronic Obstructive Pulmonary Disease (COPD) Patients | COMPLETED | PHASE2 | 2008-10 | 2010-04 | 2010-01 |
| NCT00791765 | Moderate to Severe Plaque Psoriasis With Scalp Involvement | COMPLETED | PHASE4 | 2008-10 | 2010-03 | 2010-01 |
| NCT00757042 | Safety Study of Tezepelumab (AMG 157) in Healthy Adults and Adults With Atopic Dermatitis | COMPLETED | PHASE1 | 2008-09-18 | 2011-01-05 | 2011-01-05 |
| NCT00436748 | Study to Assess Darbepoetin Alfa Dosing for the Correction of Anemia in Pediatric Patients With Chronic Kidney Disease | TERMINATED | PHASE3 | 2008-09-16 | 2014-03-03 | 2014-03-03 |
| NCT00680992 | Study of Denosumab in Subjects With Giant Cell Tumor of Bone | COMPLETED | PHASE2 | 2008-09-09 | 2018-05-17 | 2018-05-17 |
| NCT00773734 | Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate-to-Severe Plaque-Type Psoriasis (Core Study) | COMPLETED | PHASE2 | 2008-09-01 | 2015-05-20 | 2009-08-01 |
| NCT00614523 | Romiplostim Treatment of Thrombocytopenia in Subjects With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) | COMPLETED | PHASE2 | 2008-07-21 | 2015-11-30 | 2011-03-31 |
| NCT00752414 | A Phase 1b Study to Evaluate the Safety and PK of MP-376 in Chronic Obstructive Pulmonary Disease (COPD) Patients | COMPLETED | PHASE1 | 2008-07 | 2008-10 | 2008-10 |
| NCT00677365 | Safety, Tolerability and Efficacy of MP-376 Given for 28 Days to Cystic Fibrosis (CF) Patients | COMPLETED | PHASE2 | 2008-06 | 2009-06 | 2009-06 |
| NCT00686335 | A New Modified-release Tablet Formulation of Prednisone (Lodotra®) in Patients With Nocturnal Asthma | COMPLETED | PHASE2 | 2008-06 | 2010-05 | 2010-03 |
| NCT00661921 | A Randomized Double Blind, Placebo Controlled Trial With AMG 108 in Patients With Type 2 Diabetes Mellitus | WITHDRAWN | PHASE2 | 2008-06 | 2009-10 | 2009-06 |
| NCT00654368 | CAMEO: Canadian Methotrexate and Etanercept Outcome Study | COMPLETED | PHASE4 | 2008-06 | 2013-02 | 2012-12 |
| NCT00603447 | Phase 1b Multicenter Study of Carfilzomib With Lenalidomide and Dexamethasone in Relapsed Multiple Myeloma | COMPLETED | PHASE1 | 2008-05 | 2016-01 | 2013-05 |
| NCT00756860 | A Phase 1 Multiple Dose Study to Compare the Effects of AMG 223 and Sevelamer HCL (Renagel®) | COMPLETED | PHASE1 | 2008-05 | 2009-09 | 2008-08 |
| NCT00661141 | Phase IIa Study of Fomepizole for Acetaldehyde Toxicity After Ethanol Exposure in Subjects With Altered Ethanol Metabolism | COMPLETED | PHASE2 | 2008-04 | 2008-06 | 2008-06 |
| NCT00650078 | Study to Assess the Safety and Efficacy of Modified-Release Prednisone (Lodotra®) Therapy in Patients With Active Rheumatoid Arthritis | COMPLETED | PHASE3 | 2008-03 | 2009-05 | 2009-05 |
| NCT00658658 | Panitumumab in Children With Solid Tumors | COMPLETED | PHASE1 | 2008-03 | 2015-03 | 2015-03 |
| NCT00563316 | Effect of Panitumumab on the Pharmacokinetics of Irinotecan | COMPLETED | PHASE1 | 2008-03 | 2010-06 | 2009-03 |
| NCT00530114 | Study to Assess Fixed Dosing of AMG 223 in Subjects With Chronic Kidney Disease on Hemodialysis With Hyperphosphatemia | COMPLETED | PHASE2 | 2008-03 | 2009-02 | 2008-11 |
| NCT00635596 | Phase I Study of MT110 in Lung Cancer (Adenocarcinoma and Small Cell), Gastric Cancer or Adenocarcinoma of the Gastro-Esophageal Junction, Colorectal Cancer, Breast Cancer, Hormone-Refractory Prostate Cancer, and Ovarian Cancer | COMPLETED | PHASE1 | 2008-03 | 2015-01 | 2014-01 |
| NCT00791011 | Phase 1b Lymphoma Study of AMG 655 in Combination With Bortezomib or Vorinostat | COMPLETED | PHASE1 | 2008-02 | 2011-08 | 2010-07 |
| NCT00534027 | A Phase 1b/2 Study of AMG 655 in Combination With Paclitaxel and Carboplatin for the First-Line Treatment of Advanced Non-Small Cell Lung Cancer | COMPLETED | PHASE1, PHASE2 | 2008-01 | 2011-03 | 2011-03 |
| NCT00560794 | Phase II Study of the BiTE® Blinatumomab (MT103) in Patients With Minimal Residual Disease of B-precursor Acute Lymphoblastic Leukemia (ALL) | COMPLETED | PHASE2 | 2008-01 | 2014-11 | 2009-09 |
| NCT00630786 | Conatumumab/Panitumumab Combination Metastatic Colorectal Cancer Study | COMPLETED | PHASE1, PHASE2 | 2008-01 | 2010-11 | 2009-05 |
| NCT00597909 | Efficacy and Safety Study of Ammonul® in Patients With Grade 3 or 4 Hepatic Encephalopathy | TERMINATED | PHASE2 | 2007-12 | 2008-09 | 2008-09 |
| NCT02291588 | A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 811 in Subjects With Systemic Lupus Erythematosus | COMPLETED | PHASE1 | 2007-12 | 2010-06 | 2010-03 |
| NCT00583674 | Phase 2 Study of AMG 386 (20060439) in Combination With Cisplatin & Capecitabine in Subjects With Metastatic Gastric, Gastroesophageal Junction, or Distal Esophageal Adenocarcinoma | COMPLETED | PHASE2 | 2007-12 | 2012-06 | 2010-03 |
| NCT01825785 | A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Romosozumab (AMG 785) | COMPLETED | PHASE1 | 2007-11-14 | 2008-12-02 | 2008-12-02 |
| NCT00547157 | Radiotherapy Plus Panitumumab Compared to Chemoradiotherapy With Unresected, Locally Advanced Squamous Cell Carcinoma of the Head and Neck | COMPLETED | PHASE2 | 2007-11 | 2012-03 | 2011-12 |
| NCT00626704 | Phase 1b/2 Study of AMG 655 With Doxorubicin for the First-Line Treatment of Unresectable Soft Tissue Sarcoma | COMPLETED | PHASE1, PHASE2 | 2007-11 | 2011-03 | 2009-08 |
| NCT00446446 | PRISM (Panitumumab Regimen In Second-line Monotherapy of Head and Neck Cancer) | COMPLETED | PHASE2 | 2007-10-30 | 2017-11-29 | 2010-12-15 |
| NCT00540657 | A Phase II Study of CCX282-B in Patients With Celiac Disease | COMPLETED | PHASE2 | 2007-10 | 2008-07 | 2008-06 |
| NCT00551200 | Dose-Escalation Safety Study of HPN-100 to Treat Urea Cycle Disorders | COMPLETED | PHASE2 | 2007-10 | 2008-12 | 2008-07 |
| NCT00603642 | P3 Study to Evaluate Efficacy and Safety of AMG 531 in Thrombocytopenic Japanese Subjects With Immune (Idiopathic) Thrombocytopenic Purpura | COMPLETED | PHASE3 | 2007-10-01 | 2009-04-13 | 2009-04-13 |
| NCT00500760 | Study of Addition of Panitumumab to Chemoradiation Therapy in Patients With Locally Advanced Head and Neck Cancer | COMPLETED | PHASE2 | 2007-10-01 | 2011-04-26 | 2011-03-29 |
| NCT00625651 | Phase 1b/2 Study of AMG 655 With mFOLFOX6 and Bevacizumab for First-Line Metastatic Colorectal Cancer | COMPLETED | PHASE1, PHASE2 | 2007-10 | 2011-09 | 2010-08 |
| NCT00613106 | Double-Blind Follow-on Safety Study of HZT-501 (Ibuprofen 800 mg/Famotidine 26.6 mg) in Subjects Who Have Completed Participation in HZ-CA-301 (NCT00450658) or HZ-CA-303 (NCT00450216) | COMPLETED | PHASE3 | 2007-09 | 2008-10 | 2008-10 |
| NCT00518531 | Denosumab Adherence Preference Satisfaction Study | COMPLETED | PHASE3 | 2007-09-01 | 2010-06-01 | 2009-06-01 |
| NCT00531284 | Phase 1b/2 Study of Carfilzomib in Relapsed Solid Tumors, Multiple Myeloma, or Lymphoma | COMPLETED | PHASE1, PHASE2 | 2007-09 | 2017-05-22 | 2014-10 |
| NCT00530816 | Phase 2 Study of Carfilzomib in Relapsed Multiple Myeloma | COMPLETED | PHASE2 | 2007-09 | 2013-07 | 2013-01 |
| NCT00523341 | Extension Study to Evaluate the Long Term Safety and Efficacy of Denosumab in the Treatment of Osteoporosis | COMPLETED | PHASE3 | 2007-08-07 | 2015-07-19 | 2015-07-19 |
| NCT00521339 | Apremilast Safety and PK Study in Recalcitrant Plaque Psoriasis | COMPLETED | PHASE2 | 2007-08-01 | 2009-05-01 | 2009-04-01 |
| NCT00511238 | Phase 2 Study of Carfilzomib in Relapsed and Refractory Multiple Myeloma | COMPLETED | PHASE2 | 2007-08 | 2012-10 | 2010-11 |
| NCT00479817 | Phase 2 AMG 386 in Comb. Paclitaxel for Subjects With Advanced Recurrent Epithelial Ovarian or Primary Peritoneal Cancer | COMPLETED | PHASE2 | 2007-07-05 | 2019-12-09 | 2009-08-11 |
| NCT00511459 | Phase 2 Study of AMG 386 Plus Paclitaxel With or Without Bevacizumab as First Line Therapy in Her2-Negative Breast Cancer Patients | COMPLETED | PHASE2 | 2007-07 | 2014-05 | 2010-08 |
| NCT00460317 | MONET1-MOtesanib NSCLC Efficacy and Tolerability Study | TERMINATED | PHASE3 | 2007-07 | 2013-08 | 2011-03 |
| NCT00515203 | Safety and Efficacy Study of Romiplostim (AMG 531) to Treat ITP in Pediatric Subjects | COMPLETED | PHASE1, PHASE2 | 2007-07 | 2009-08 | 2009-03 |
| NCT00503490 | Safety, Pharmacokinetic and Pharmacodynamic Study of MP-376 in Patients With Cystic Fibrosis | COMPLETED | PHASE1 | 2007-06 | 2007-12 | 2007-12 |
| NCT00508404 | Panitumumab Plus FOLFIRI in First-line Treatment of Metastatic Colorectal Cancer | COMPLETED | PHASE2 | 2007-05-09 | 2012-06-12 | 2009-06-01 |
| NCT00467025 | AMG 386, 20060159 Phase 2, RCC 1st Line in Combination With Sorafenib | COMPLETED | PHASE2 | 2007-05 | 2014-06 | 2010-04 |
| NCT00460265 | Study of Panitumumab Efficacy in Patients With Recurrent and/or Metastatic Head and Neck Cancer | COMPLETED | PHASE3 | 2007-05 | 2012-05 | 2010-05 |
| NCT00515463 | A Multi-Center, Randomized, Open-Label Study to Assess the Immunogenicity and Safety of Denosumab in Pre-filled Syringe Compared to Vial in Subjects With Low Bone Mineral Density | COMPLETED | PHASE3 | 2007-05 | 2009-03 | 2008-03 |
| NCT00472290 | Evaluating the Safety of Long Term Dosing of Romiplostim (Formerly AMG 531) in Thrombocytopenic Subjects With Myelodysplastic Syndromes (MDS) | COMPLETED | NA | 2007-04-01 | 2011-12-26 | 2011-07-18 |
| NCT00456092 | Phase II Study of Apremilast (CC-10004) in Adults With in Psoriatic Arthritis | COMPLETED | PHASE2 | 2007-03-05 | 2009-05-09 | 2009-05-09 |
| NCT00450216 | Efficacy and Safety Study of HZT-501 in Subjects Requiring Nonsteroidal Anti-Inflammatory Drug (NSAID) Treatment | COMPLETED | PHASE3 | 2007-03 | 2008-10 | 2008-08 |
| NCT00450658 | Efficacy and Safety Study of HZT-501 in Reducing the Risk of Ibuprofen-associated Ulcers | COMPLETED | PHASE3 | 2007-03 | 2008-10 | 2008-09 |
| NCT00436670 | Phase II Study to Evaluate the Efficacy of AMG 317 | COMPLETED | PHASE2 | 2007-03 | 2009-02 | 2008-09 |
| NCT00443326 | AMG 714 20060349 Multiple Dose Study in Moderate to Severe Psoriasis Subjects | COMPLETED | PHASE2 | 2007-03 | 2010-05 | 2008-12 |
| NCT00448786 | Effect of Different Doses of AMG 706 on the Gallbladder in Advanced Solid Tumors | COMPLETED | PHASE1 | 2007-02 | 2009-03 | 2008-12 |
| NCT00369070 | A Phase 2 Trial of AMG 706 or Bevacizumab in Combination With Chemo for Advanced NSCLC | TERMINATED | PHASE2 | 2007-01-31 | 2011-08-03 | 2008-04-23 |
| NCT00454779 | PARTNER: Panitumumab Added to Regimen for Treatment of Head aNd Neck Cancer Evaluation of Response | COMPLETED | PHASE2 | 2007-01-01 | 2014-01-01 | 2012-06-11 |
| NCT00422019 | A Phase II Study to Treat Subjects With Advanced Renal Cell Carcinoma | COMPLETED | PHASE2 | 2007-01 | 2009-03 | 2009-03 |
| NCT00613730 | Adenocarcinoma of the Pancreas Treated With Panitumumab and Gemcitabine Regimen to Investigate Overall Survival as Primary Endpoint | TERMINATED | PHASE2 | 2007-01 | 2009-04 | 2009-04 |
| NCT00534456 | An Exploratory Sub-study for the RED-HF™ (Reduction of Events With Darbepoetin Alfa in Heart Failure) Trial | TERMINATED | PHASE3 | 2007-01 | 2007-10 | 2007-10 |
| NCT00556374 | Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy | COMPLETED | PHASE3 | 2006-12-18 | 2022-07-26 | 2014-10-07 |
| NCT01059435 | A First-in-human Study Evaluating Romosozumab (AMG 785) in Healthy Men and Postmenopausal Women | COMPLETED | PHASE1 | 2006-12-13 | 2007-07-06 | 2007-07-06 |
| NCT00415532 | Romiplostim (AMG 531) Versus Medical Standard of Care for Immune (Idiopathic) Thrombocytopenic Purpura | COMPLETED | PHASE3 | 2006-12-01 | 2009-05-11 | 2008-11-07 |
| NCT00356681 | A Study of AMG 706 or Bevacizumab, in Combination With Paclitaxel Chemotherapy, as Treatment for Breast Cancer | TERMINATED | PHASE2 | 2006-12 | 2012-08 | 2009-02 |
| NCT02318407 | A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 403 in Subjects With Osteoarthritis Knee Pain | COMPLETED | PHASE1 | 2006-12 | 2008-03 | 2008-01 |
| NCT00401544 | Darbepoetin Alfa With or Without Intravenous (IV) Iron | COMPLETED | PHASE2 | 2006-12 | 2008-03 | 2007-12 |
| NCT00413283 | Dose/ Schedule Finding Trial of Romiplostim for Chemotherapy-Induced Thrombocytopenia (CIT) in Non-Small Cell Lung Cancer (NSCLC) | COMPLETED | PHASE2 | 2006-12 | 2009-02 | 2008-12 |
| NCT00418665 | A Safety and Efficacy Study to Evaluate AMG 531 Treatment in Subject With Myelodysplastic Syndrome Receiving Revlimid | COMPLETED | PHASE2 | 2006-12 | 2010-10 | 2009-03 |
| NCT00413452 | Etanercept SFP in RA Patients | COMPLETED | PHASE3 | 2006-12 | 2007-10 | 2007-08 |
| NCT00418938 | SPIRITT - Second-Line Panitumumab Irinotecan Treatment Trial | COMPLETED | PHASE2 | 2006-11-01 | 2013-04-01 | 2012-05-10 |
| NCT00411450 | Panitumumab Regimen Evaluation in Colorectal Cancer to Estimate Primary Response to Treatment | COMPLETED | PHASE2 | 2006-11 | 2010-10 | 2009-01 |
| NCT00427440 | A Phase II Study to Treat Advanced Malignant Glioma | COMPLETED | PHASE2 | 2006-11 | 2013-04 | 2008-12 |
| NCT02391259 | A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of AMG 557 in Subjects With Systemic Lupus Erythematosus | COMPLETED | PHASE1 | 2006-11 | 2011-11 | 2011-09 |
| NCT00321711 | Determination of Safe and Effective Dose of Romiplostim (AMG 531) in Subjects With Myelodysplastic Syndrome (MDS)Receiving Hypomethylating Agents | COMPLETED | PHASE2 | 2006-10-01 | 2009-10-19 | 2009-10-19 |
| NCT00986895 | A Study of Glyceryl Tri-(4-phenylbutyrate) Administered Orally as a Single Dose, and Twice Daily for Seven Consecutive Days to Subjects With Hepatic Impairment With Cirrhosis and to a Control Group | COMPLETED | PHASE1 | 2006-09 | 2007-06 | |
| NCT00369473 | Long-Term Assessment of Safety and Physical Function With AMG 108 in RA | COMPLETED | PHASE2 | 2006-09 | 2008-06 | 2008-06 |
| NCT00379899 | ADVANCE: Study to Evaluate Cinacalcet Plus Low Dose Vitamin D on Vascular Calcification in Subjects With Chronic Kidney Disease Receiving Hemodialysis | COMPLETED | PHASE4 | 2006-09 | 2009-11 | 2009-05 |
| NCT00364845 | STIMULATE Study: Anemia Correction and Health-related Quality of Life (HRQoL) Outcomes in Elderly Chronic Kidney Disease (CKD) Patients | TERMINATED | PHASE3 | 2006-09 | 2009-02 | 2008-12 |
| NCT00361634 | Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Measure Response to Etanercept in Rheumatoid Arthritis | COMPLETED | PHASE1 | 2006-09 | 2010-03 | 2009-08 |
| NCT00431496 | A Study of Cinacalcet to Improve Achievement of National Kidney Foundation Kidney Disease Outcomes Quality Initiative (K/DOQI) Targets in Patients With End Stage Renal Disease (ESRD) | COMPLETED | PHASE4 | 2006-09 | 2009-10 | 2009-06 |
| NCT00377819 | Study of Transitioning From Alendronate to Denosumab | COMPLETED | PHASE3 | 2006-09 | 2008-07 | 2008-03 |
| NCT00345839 | E.V.O.L.V.E. Trial™: EValuation Of Cinacalcet Hydrochloride (HCl) Therapy to Lower CardioVascular Events | COMPLETED | PHASE3 | 2006-08-22 | 2012-04-10 | 2012-04-10 |
| NCT00364013 | PRIME: Panitumumab Randomized Trial In Combination With Chemotherapy for Metastatic Colorectal Cancer to Determine Efficacy | COMPLETED | PHASE3 | 2006-08-01 | 2013-03-22 | 2009-08-01 |
| NCT00396279 | Safety and Efficacy Study of Denosumab in Patients With Recurrent or Unresectable Giant Cell Tumor of Bone | COMPLETED | PHASE2 | 2006-07-10 | 2011-02-01 | 2008-04-07 |
| NCT00339183 | Comparison of Treatment Effect of Chemotherapy With Panitumumab to Chemotherapy Alone | COMPLETED | PHASE3 | 2006-06-30 | 2010-11-01 | 2009-04-01 |
| NCT00330759 | Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma. | COMPLETED | PHASE3 | 2006-06-01 | 2011-10-01 | 2009-04-01 |
| NCT00358215 | RED-HF™ Trial - Reduction of Events With Darbepoetin Alfa in Heart Failure Trial | COMPLETED | PHASE3 | 2006-06-01 | 2012-10-11 | 2012-10-11 |
| NCT00508625 | A Study of AMG 951 [rhApo2L/TRAIL] in Subjects With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) Treated With Chemotherapy +/- Bevacizumab | COMPLETED | PHASE2 | 2006-06 | 2011-11 | 2009-03 |
| NCT00325468 | An Open-label, Single-arm Extension Study to Evaluate the Long-term Safety of Denosumab Administration in Postmenopausal Women With Low Bone Mineral Density | COMPLETED | PHASE3 | 2006-05-01 | 2012-08-02 | 2011-03-28 |
| NCT00293813 | A Multicenter, Randomized Placebo Controlled Pilot MicroCT Study to Estimate the Effect of Treatment With Denosumab (AMG 162) and Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density | COMPLETED | PHASE2 | 2006-05 | 2008-08 | 2008-03 |
| NCT00261950 | Bone Biopsy Study For Dialysis Patients With Secondary Hyperparathyroidism of End Stage Renal Disease | COMPLETED | PHASE2 | 2006-05 | 2011-05 | 2011-05 |
| NCT00330460 | A Randomized, Double-Blind Study to Compare the Efficacy of Treatment With Denosumab Versus Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density. | COMPLETED | PHASE3 | 2006-05 | 2008-01 | 2007-11 |
| NCT00321464 | A Study Comparing Denosumab vs. Zoledronic Acid for the Treatment of Bone Metastases in Breast Cancer Subjects. | COMPLETED | PHASE3 | 2006-04-01 | 2012-04-04 | 2009-07-20 |
| NCT00606450 | Double-Blind, Randomized, Placebo-controlled Comparison of CC-10004 in Subjects With Moderate to Severe Plaque Type Psoriasis | COMPLETED | PHASE2 | 2006-04-01 | 2007-05-01 | 2007-02-01 |
| NCT00321620 | Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Men With Hormone-refractory Prostate Cancer | COMPLETED | PHASE3 | 2006-04-01 | 2012-02-24 | 2009-10-01 |
| NCT00332163 | Skin Toxicity Treatment in Metastatic Colorectal Cancer (mCRC) Patients Receiving Panitumumab + Irinotecan-based Therapy | COMPLETED | PHASE2 | 2006-04 | 2008-09 | 2008-01 |
| NCT00436995 | Extension From Weekly to Once Every Other Week Darbepoetin Alfa Administration in Subjects With Chronic Kidney Disease Receiving Dialysis | COMPLETED | PHASE3 | 2006-04 | 2008-12 | 2007-01 |
| NCT00327119 | Phase 2 Study of ABX-EGF (Panitumumab) in Japanese Subjects With M-colorectal Cancer | COMPLETED | PHASE2 | 2006-04 | | |
| NCT00306215 | A Study to Evaluate the Efficacy and Safety of CCX282-B in Subjects With Moderate to Severe Crohn's Disease | COMPLETED | PHASE2 | 2006-03 | 2009-06 | 2008-08 |
| NCT00352950 | Safety Evaluation of Panitumumab and Sirolimus in Advanced Non-Small Cell Lung Cancer | WITHDRAWN | PHASE1 | 2006-03 | 2008-02 | |
| NCT00332332 | Canadian Assessment of Patient Outcomes and Effectiveness of Etanercept (Enbrel) in Psoriasis | COMPLETED | PHASE4 | 2006-03 | 2010-02 | 2009-07 |
| NCT00322400 | Phase1b to Evaluate Safety of AMG706 in Combination With Paclitaxel or Docetaxel for Breast Cancer | COMPLETED | PHASE1 | 2006-03 | 2012-01 | 2009-04 |
| NCT00293826 | A Multiple Dose Study to Evaluate Subcutaneous AMG 108 in Subjects With Rheumatoid Arthritis | COMPLETED | PHASE2 | 2006-03 | 2008-02 | 2007-11 |
| NCT00303472 | Determination of Safe Dose of Romiplostim (AMG 531) in Patients With Myelodysplastic Syndromes (MDS) | COMPLETED | PHASE2 | 2006-02 | 2008-05 | 2008-05 |
| NCT00286091 | Study on Prolonging Bone Metastasis-Free Survival in Men With Hormone Refractory Prostate Cancer | COMPLETED | PHASE3 | 2006-01-24 | 2014-04-09 | 2010-07-30 |
| NCT00346294 | An Open-Label Study to Assess the Rate of Failure of an Enbrel® (Etanercept) SureClick™ Auto-injector in Subjects With Rheumatoid Arthritis | COMPLETED | PHASE4 | 2006-01 | 2006-07 | 2006-03 |
| NCT00306189 | A Randomized, Double-blind, Placebo-controlled, Dose Response Study of AMG 162 (Denosumab) in Japanese Postmenopausal Osteoporotic Subjects | COMPLETED | PHASE2 | 2006-01 | 2007-11 | 2007-06 |
| NCT00861419 | To Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 386 When Used in Combination With AMG 706, Bevacizumab, Sorafenib, or Sunitinib. | COMPLETED | PHASE1 | 2005-12 | | |
| NCT00360867 | An Open Label Treatment Extension Study of AMG 706 | TERMINATED | PHASE2 | 2005-12 | 2012-07 | 2012-07 |
| NCT00261313 | ACCELERATE: Doxorubicin and Cyclophosphamide Followed by Paclitaxel With Pegfilgrastim and Darbepoetin Alfa Support for the Treatment of Women With Breast Cancer | COMPLETED | PHASE2 | 2005-12 | 2007-12 | 2007-06 |
| NCT00259740 | Open-Label, Phase 2, Proof of Concept Study in Multiple Myeloma - Denosumab | COMPLETED | PHASE2 | 2005-11 | 2011-12 | 2007-08 |
| NCT00254267 | Evaluate the Efficacy of AMG 706 to Treat Advanced Gastrointestinal Stromal Tumors | COMPLETED | PHASE2 | 2005-11 | 2012-12 | 2007-02 |
| NCT00283439 | A Dose and Schedule Finding Trial With AMG 531 for Chemotherapy Induced Thrombocytopenia (CIT) in Adults With Lymphoma | COMPLETED | PHASE1, PHASE2 | 2005-10 | 2008-09 | 2008-05 |
| NCT00249041 | Enbrel Liquid Immunogenicity Protocol | COMPLETED | PHASE3 | 2005-10 | 2007-03 | 2006-12 |
| NCT00150462 | Safety Study of the Proteasome Inhibitor PR-171 (Carfilzomib for Injection) in Patients With Hematological Malignancies | COMPLETED | PHASE1 | 2005-09 | 2009-10 | 2009-10 |
| NCT01235416 | A Phase 1b, Open-label, Dose-finding Study of AMG 706 in Combination With Gemcitabine and Erlotinib to Treat Subjects With Solid Tumors | COMPLETED | PHASE1 | 2005-09 | 2010-02 | 2008-04 |
| NCT00146224 | Efficacy of Epoetin Alfa Deep Tank in Treatment of Anemia in Patients With Chronic Kidney Disease Receiving Hemodialysis | COMPLETED | PHASE3 | 2005-09 | 2007-01 | 2007-01 |
| NCT00141921 | Pediatric Open-Label Extension Study of Etanercept in Patients With Plaque Psoriasis | COMPLETED | PHASE3 | 2005-08-11 | 2017-08-16 | 2011-12-19 |
| NCT00393822 | A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Stage 2B or 3 Locally Advanced, Colon Cancer | COMPLETED | PHASE2, PHASE3 | 2005-08 | 2014-03 | 2007-12 |
| NCT00127842 | REPArE: Rating Evaluations in Psoriatic Arthritis (PsA) With Etanercept (Enbrel®) | COMPLETED | PHASE4 | 2005-08 | 2009-09 | 2005-08 |
| NCT00135304 | ACHIEVE: Optimizing the Treatment of Secondary Hyperparathyroidism | COMPLETED | PHASE4 | 2005-08 | 2006-12 | 2006-10 |
| NCT00144131 | Flexibility: A Study to Assess the Impact of Darbepoetin Alfa in Subjects withNon-Myeloid Malignancies With Anemia Due to Chemotherapy | COMPLETED | PHASE2 | 2005-08 | | |
| NCT00239239 | Fractionated Dosing Study: Study to Evaluate Darbepoetin Alfa for the Treatment of Anemia in Subjects With Non-Myeloid Malignancies | COMPLETED | PHASE2 | 2005-08 | 2007-03 | 2007-01 |
| NCT00121628 | A Phase 2, Open-label Study of AMG 706 to Treat Subjects With Locally Advanced or Metastatic Thyroid Cancer | COMPLETED | PHASE2 | 2005-07 | 2010-10 | 2006-11 |
| NCT00115765 | PACCE: Panitumumab Advanced Colorectal Cancer Evaluation Study | COMPLETED | PHASE3 | 2005-06-01 | 2009-05-01 | 2007-05-31 |
| NCT02411136 | A Study to Examine the Safety, Pharmacokinetics and Pharmacodynamics of AMG 623 in Subjects With Systemic Lupus Erythematosus | COMPLETED | PHASE1 | 2005-05 | 2007-10 | 2007-08 |
| NCT00115219 | Evaluating Efficacy and Safety of Etanercept 50 mg Twice Weekly (BIW) in Rheumatoid Arthritis (RA) Subjects Who Are Sub-Optimal Responders to Etanercept 50 mg Once Weekly (QW) | COMPLETED | PHASE4 | 2005-05 | | |
| NCT00116701 | Treatment for Subjects With Chronic Kidney Disease Receiving Haemodialysis | COMPLETED | PHASE3 | 2005-05 | | |
| NCT00102336 | AMG 531 Treatment of Thrombocytopenic Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) Prior to Splenectomy | COMPLETED | PHASE3 | 2005-04-07 | 2007-04-01 | 2006-12-01 |
| NCT00156949 | EPO Deep Tank in Dialysis Subjects | COMPLETED | PHASE3 | 2005-04 | 2007-02 | 2007-02 |
| NCT00156962 | Epoetin Alfa (EPO) in Subjects With Chronic Kidney Disease (CKD) | TERMINATED | PHASE3 | 2005-04 | 2007-03 | 2007-03 |
| NCT00102323 | AMG 531 Treatment of Thrombocytopenic Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) Refractory to Splenectomy | COMPLETED | PHASE3 | 2005-03-29 | 2007-03-01 | 2006-09-01 |
| NCT00977600 | A Study of Glyceryl Tri-(4-phenylbutyrate) (GT4P) | COMPLETED | PHASE1 | 2005-03 | 2005-07 | |
| NCT00110981 | Utilization of Narrow Band Ultraviolet B (UVB) Light Therapy and Etanercept for the Treatment of Psoriasis | COMPLETED | PHASE4 | 2005-03 | 2006-03 | 2006-02 |
| NCT00121602 | Efficacy Study: Darbepoetin Alfa for the Treatment of Anemia in Patients With Chronic Kidney Disease | COMPLETED | PHASE3 | 2005-03 | 2006-10 | 2005-10 |
| NCT00508820 | An Open Label Study of Romiplostim in Adult Thrombocytopenic Subjects With ITP | COMPLETED | PHASE3 | 2005-02-01 | 2011-03-01 | 2011-01-01 |
| NCT00110942 | Treatment for Patients With Osteoarthritis (OA) | COMPLETED | PHASE2 | 2005-02 | 2005-11 | 2005-06 |
| NCT00604682 | Open-Label,Single-Arm Pilot Study to Evaluate the Pharmacodynamics, Pharmacokinetics, Safety, and Preliminary Efficacy of CC1004 in Subjects With Severe Plaque Type Psoriasis | COMPLETED | PHASE2 | 2005-01-01 | 2005-12-01 | 2005-10-01 |
| NCT00131638 | A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer | COMPLETED | PHASE3 | 2005-01 | 2016-07 | 2007-11 |
| NCT00094835 | Study to Evaluate Motesanib With or Without Carboplatin/Paclitaxel or Panitumumab in the Treatment of Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) | COMPLETED | PHASE1, PHASE2 | 2005-01 | 2007-03 | 2007-03 |
| NCT02348879 | A Study to Examine the Safety, Pharmacokinetics and Pharmacodynamics of AMG 403 in Healthy Subject | COMPLETED | PHASE1 | 2005-01 | 2006-03 | 2006-01 |
| NCT00104650 | Study of AMG 162 in Subjects With Advanced Cancer Currently Being Treated With Intravenous (IV) Bisphosphonates | COMPLETED | PHASE2 | 2005-01 | 2010-03 | 2008-01 |
| NCT00101907 | Safety of AMG 706 Plus Panitumumab Plus Gemcitabine-Cisplatin in the Treatment of Patients With Advanced Cancer | TERMINATED | PHASE1 | 2004-12 | 2008-04 | 2007-06 |
| NCT00101894 | Safety of AMG 706 Plus Panitumumab Plus Chemotherapy in the Treatment of Subjects With Metastatic Colorectal Cancer | COMPLETED | PHASE1 | 2004-12 | 2011-12 | 2010-04 |
| NCT00135317 | AIM 3: Anemia and Iron Management With Every 3 Week Dosing in Anemic Subjects With Nonmyeloid Malignancies | COMPLETED | PHASE3 | 2004-11 | | |
| NCT00089661 | AMG 162 in the Treatment of Bone Loss in Subjects Undergoing Aromatase Inhibitor Therapy for Non-metastatic Breast Cancer | COMPLETED | PHASE3 | 2004-10-01 | 2009-05-27 | 2007-05-11 |
| NCT02443506 | A Study to Examine the Safety, Pharmacokinetics and Pharmacodynamics of Single Dose of AMG 623 in Subjects With Systemic Lupus Erythematosus | COMPLETED | PHASE1 | 2004-10 | 2007-06 | 2007-04 |
| NCT00093977 | Study to Assess Darbepoetin Alfa in Subjects With Chronic Kidney Disease | COMPLETED | PHASE3 | 2004-10 | 2007-01 | 2007-01 |
| NCT00094484 | Cinacalcet HCl in Chronic Kidney Disease Subjects With Secondary Hyperparathyroidism Not Receiving Dialysis | COMPLETED | PHASE3 | 2004-10 | | |
| NCT00089960 | Study of AMG 706 in Subjects With Advanced Gastrointestinal Stromal Tumors (GISTs) | COMPLETED | PHASE2 | 2004-10 | 2008-06 | 2006-06 |
| NCT00095264 | A Study of Darbepoetin Alfa in Anemic Subjects With Low Risk Myelodysplastic Syndrome | COMPLETED | PHASE2 | 2004-10 | | |
| NCT00096915 | Study Evaluating Darbepoetin Alfa in Subjects With Chronic Kidney Disease (CKD) Receiving Dialysis | COMPLETED | PHASE3 | 2004-10 | 2005-11 | 2005-11 |
| NCT00095277 | Darbepoetin Alfa Administered Once Every 4 Weeks in the Treatment of Subjects With Anemia of Cancer | COMPLETED | PHASE2 | 2004-10 | | |
| NCT00121615 | Study of Etanercept in the Treatment of Psoriasis in Adult Subjects | COMPLETED | PHASE3 | 2004-10 | | |
| NCT00094341 | Preference of Rheumatoid Arthritis (RA) Patients of Enbrel® (Etanercept) Auto-Injector Versus Enbrel® Pre-Filled Syringes | COMPLETED | PHASE4 | 2004-10 | | |
| NCT00078819 | Etanercept (Enbrel®) in Psoriasis - Pediatrics | COMPLETED | PHASE3 | 2004-09-08 | 2007-06-01 | 2006-02-01 |
| NCT00091832 | Denosumab (AMG 162) in Bisphosphonate Naive Metastatic Breast Cancer | COMPLETED | PHASE2 | 2004-09 | 2006-10 | 2005-11 |
| NCT00117052 | SENSOR: Study to Investigate Cinacalcet Treatment in Haemodialysis Patients With Secondary Hyperparathyroidism | COMPLETED | PHASE3 | 2004-09 | 2006-02 | 2005-11 |
| NCT00095498 | Efficacy, Safety and Tolerability of Denosumab in the Treatment of Rheumatoid Arthritis | COMPLETED | PHASE2 | 2004-08-11 | 2007-04-01 | 2007-04-01 |
| NCT00102921 | Safety and Activity Study of an Oral Medication to Treat Moderate to Severe Crohn's Disease | COMPLETED | PHASE2 | 2004-08 | 2005-12 | |
| NCT00089635 | Panitumumab (ABX-EGF) Monotherapy in Patients With Metastatic Colorectal Cancer | COMPLETED | PHASE2 | 2004-08-01 | 2008-08-01 | 2007-01-01 |
| NCT00089791 | A Study to Evaluate Denosumab in the Treatment of Postmenopausal Osteoporosis | COMPLETED | PHASE3 | 2004-08-01 | 2008-06-17 | 2008-06-17 |
| NCT00093015 | Trial to Reduce Cardiovascular Events With Aranesp® Therapy (TREAT) | COMPLETED | PHASE3 | 2004-08-01 | 2009-07-01 | 2009-03-01 |
| NCT00089674 | AMG 162 in the Treatment of Bone Loss in Subjects Undergoing Androgen-Deprivation Therapy for Non-metastatic Prostate Cancer | COMPLETED | PHASE3 | 2004-08-01 | 2010-05-11 | 2008-05-16 |
| NCT02588534 | Open-label Study Using 50 Mg Liquid Etanercept Subcutaneous Injection in the Thigh to Compare an Auto-injector Device and a Manual Injection in Healthy Subjects | COMPLETED | PHASE1 | 2004-08 | 2004-10 | 2004-10 |
| NCT00116688 | Open Label Extension Study of Romiplostim (AMG 531) in Thrombocytopenic Patients With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) | COMPLETED | PHASE3 | 2004-08 | 2010-01 | 2010-01 |
| NCT00091793 | Study to Evaluate AMG 162 in the Prevention of Postmenopausal Osteoporosis | COMPLETED | PHASE3 | 2004-08 | 2009-03 | 2009-02 |
| NCT00091806 | Two Dose Schedules of Panitumumab in Subjects With Advanced Solid Tumors | COMPLETED | PHASE1 | 2004-08 | 2006-10 | 2006-04 |
| NCT00115167 | A Study of Darbepoetin Alfa in Anemic Subjects Not Receiving Chemotherapy Who Have Completed the 20010103 Study | COMPLETED | PHASE3 | 2004-08 | 2007-03 | 2007-01 |
| NCT00132431 | START: Sensipar Treatment Algorithm to Reach K/DOQI Targets in Chronic Kidney Disease Subjects With Secondary Hyperparathyroidism | COMPLETED | PHASE4 | 2004-07 | 2005-07 | |
| NCT00274742 | Safety Study of the Bispecific T-cell Engager Blinatumomab (MT103) in Patients With Relapsed NHL | COMPLETED | PHASE1 | 2004-06 | 2012-04 | 2011-08 |
| NCT00110916 | Treatment for Patients With Osteoarthritis (OA) of the Knee | COMPLETED | PHASE2 | 2004-06 | 2005-02 | 2005-02 |
| NCT00110890 | A Research Study for Patients With End-Stage Renal Disease (ESRD) | COMPLETED | PHASE4 | 2004-05 | 2007-09 | 2005-04 |
| NCT00125723 | FIRST - Study of Pegfilgrastim Administered in the First and Subsequent Cycles of Myelosuppressive Chemotherapy | COMPLETED | PHASE4 | 2004-05 | 2005-12 | 2005-12 |
| NCT00099554 | Effectiveness and Safety of Enbrel® (Etanercept) in Rheumatoid Arthritis Subjects Who Have Failed Remicade® (Infliximab) | COMPLETED | PHASE4 | 2004-05 | | |
| NCT00112008 | Study for Subjects With Chronic Kidney Disease(CKD) Not Receiving Dialysis | COMPLETED | PHASE3 | 2004-05 | 2005-03 | 2005-03 |
| NCT00091858 | Study of Darbepoetin Alfa for the Treatment of Anemia of Cancer | COMPLETED | PHASE3 | 2004-04 | 2006-12 | 2006-10 |
| NCT00083616 | Evaluating Panitumumab (ABX-EGF) Monotherapy in Patients With Metastatic Colorectal Cancer Following Treatment With Fluoropyrimidine, Irinotecan, and Oxaliplatin Chemotherapy | COMPLETED | PHASE2 | 2004-03 | 2008-12 | 2007-05 |
| NCT00118638 | A Study of Darbepoetin Alfa for the Treatment of Anemia in Subjects With Non-Myeloid Malignancy Receiving Multicycle Chemotherapy | COMPLETED | PHASE3 | 2004-03 | 2005-01 | 2004-12 |
| NCT00425204 | Study for Patients Who Have Benefited and Tolerated Prior Panitumumab Treatment | COMPLETED | PHASE2 | 2004-03 | 2008-03 | 2007-09 |
| NCT00111098 | Treatment for Subjects With Chronic Kidney Disease (CKD) Not Receiving Dialysis | COMPLETED | PHASE3 | 2004-03 | 2005-11 | 2005-11 |
| NCT00110955 | Treatment of Anemia in Subjects With Non-Myeloid Malignancy Receiving Multicycle Chemotherapy | COMPLETED | PHASE3 | 2004-02 | 2005-04 | 2005-03 |
| NCT00113763 | Evaluating Panitumumab (ABX-EGF) Plus Best Supportive Care Versus Best Supportive Care in Patients With Metastatic Colorectal Cancer | COMPLETED | PHASE3 | 2004-01-01 | 2009-06-01 | 2008-10-01 |
| NCT00117039 | A Study to Evaluate the Effectiveness of Aranesp® for Cancer Patients With Anemia | COMPLETED | PHASE4 | 2004-01 | 2005-04 | |
| NCT00111982 | Trial of Extended Treatment With Liatermin (r-metHuGDNF) Administered by Continuous Intraputaminal (IPu)Infusion to Subjects With Idiopathic Parkinson's Disease Who Have Completed a Previous Trial of Liatermin | COMPLETED | PHASE1, PHASE2 | 2003-12 | 2006-02 | 2005-11 |
| NCT02799498 | Compare Actions in Healthy Volunteer of 50 mg Etanercept Injection Using an Auto-injector Device and Manual Injection | COMPLETED | PHASE1 | 2003-10 | 2004-01 | 2004-01 |
| NCT00113789 | Evaluating Pegfilgrastim and a Multi-Day Topotecan Regimen in Subjects With Relapsed or Refractory Ovarian Cancer | COMPLETED | PHASE2 | 2003-10 | 2005-04 | 2005-04 |
| NCT03822078 | Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Denosumab (AMG 162) in Japanese Postmenopausal Women | COMPLETED | PHASE1 | 2003-09-30 | 2004-12-24 | 2004-12-24 |
| NCT00086086 | Subcutaneous (SC) Darbepoetin Alfa in Subjects With Symptomatic Congestive Heart Failure (CHF) & Anemia | COMPLETED | PHASE2 | 2003-08 | | |
| NCT00093873 | Study Evaluating AMG 706 in Subjects With Advanced Solid Tumors | COMPLETED | PHASE1 | 2003-07 | 2006-12 | 2006-02 |
| NCT00113945 | Research Study Evaluating Cinacalcet for Patients With End Stage Renal Disease (ESRD) | COMPLETED | PHASE2 | 2003-07 | | |
| NCT00111449 | Evaluating the Safety of Etanercept 50 mg Twice Weekly in Subjects With Psoriasis | COMPLETED | PHASE3 | 2003-06 | | |
| NCT00101920 | ABX-EGF as Second Line Treatment of Advanced Non-Small-Cell Lung Cancer (NSCLC) | COMPLETED | PHASE2 | 2003-06 | 2004-12 | 2004-12 |
| NCT00111436 | Evaluating the Safety of Etanercept in the Treatment of Psoriasis in Adult Subjects | COMPLETED | PHASE3 | 2003-04 | 2005-07 | 2005-07 |
| NCT00066092 | Pegfilgrastim PBPC Mobilization Study | COMPLETED | PHASE2 | 2003-04 | 2004-10 | 2004-03 |
| NCT00114764 | Trial Comparing Pegfilgrastim With Filgrastim as an Adjunct to Chemotherapy for Acute Myeloid Leukaemia (AML) | COMPLETED | PHASE2 | 2003-03 | 2004-08 | 2004-04 |
| NCT00115427 | Study of Liatermin (r-metHuGDNF) Administered by Bilateral Intraputaminal (IPu) Infusion to Subjects With Idiopathic Parkinson's Disease | COMPLETED | PHASE1 | 2003-03 | | |
| NCT00094809 | Chemotherapy Administered Every 2 Weeks With or Without Pegfilgrastim in Subjects With Advanced or Metastatic Colon Cancer | COMPLETED | PHASE2 | 2003-02-01 | 2008-01-23 | 2006-05-19 |
| NCT00115193 | Pegfilgrastim Administered on the Same Day as Chemotherapy in Non-Hodgkin's Lymphoma | COMPLETED | PHASE2 | 2003-02 | 2005-08 | 2005-08 |
| NCT00425035 | Safety and Efficacy Study of ABX-EGF in Patients With Renal Cancer, Part 2 | COMPLETED | PHASE2 | 2003-02 | | |
| NCT00111137 | Treatment for Patients With Non-Myeloid Malignancies Receiving Chemotherapy | COMPLETED | PHASE3 | 2003-02 | 2004-04 | 2003-11 |
| NCT00117143 | Amgen Megakaryopoiesis Protein 2 (AMG 531) in Thrombocytopenic Subjects With Immune Thrombocytopenic Purpura (ITP) | COMPLETED | PHASE1, PHASE2 | 2002-12-02 | 2004-07-19 | 2004-07-19 |
| NCT00119613 | A Study of Subjects With Previously Untreated Extensive-Stage Small-Cell Lung Cancer (SCLC) Treated With Platinum Plus Etoposide Chemotherapy With or Without Darbepoetin Alfa | COMPLETED | PHASE3 | 2002-12 | 2007-04 | 2007-01 |
| NCT00433875 | Phase 2 AMG 714 in Rheumatoid Arthritis | COMPLETED | PHASE2 | 2002-12 | | |
| NCT00117624 | A Study of Darbepoetin Alfa for the Treatment of Anemia in Subjects With a Non-Myeloid Malignancy | COMPLETED | PHASE3 | 2002-12 | 2003-12 | |
| NCT00110929 | Treatment for Patients With Secondary Hyperparathyroidism of End-Stage Renal Disease (ESRD) | COMPLETED | PHASE2 | 2002-11 | | |
| NCT00120705 | Treatment for Anemic Subjects With Non-Myeloid Malignancies Receiving Chemotherapy | COMPLETED | PHASE2 | 2002-11 | 2003-09 | |
| NCT00117910 | Treatment for Elderly Patients With High Risk Breast Cancer | COMPLETED | PHASE3 | 2002-10 | 2004-05 | |
| NCT00120679 | Treatment for Patients With Non-Small Cell Lung Cancer Who Developed Anemia Due to Chemotherapy | COMPLETED | PHASE2 | 2002-10 | 2003-12 | |
| NCT00120692 | Treatment for Patients Suffering From Anemia Due to Chemotherapy | COMPLETED | PHASE2 | 2002-10 | 2003-12 | |
| NCT00121030 | Treatment for Patients With Gynecological Malignancies Who Suffer From Anemia Due to Chemotherapy | COMPLETED | PHASE2 | 2002-10 | 2003-12 | |
| NCT00117234 | Impact of Darbepoetin Alfa on Exercise Tolerance and Left Ventricular Structure in Subjects With Symptomatic Congestive Heart Failure (CHF) and Anemia | COMPLETED | NA | 2002-09 | 2004-07 | |
| NCT00117117 | A Study to Assess Symptom Burden in Subjects With Nonmyeloid Malignancies Receiving Chemotherapy and Aranesp® | COMPLETED | PHASE4 | 2002-09 | 2003-12 | |
| NCT00117442 | A Study of Carboplatin/Paclitaxel With Pegfilgrastim Supported by Haematopoietic Progenitor Cell Re-Infusion in Whole Blood | COMPLETED | PHASE2 | 2002-08 | 2004-12 | 2004-08 |
| NCT00111423 | Evaluating the Safety of Extended Treatment With Pegsunercept (PEG sTNF-RI)in Subjects With Rheumatoid Arthritis (RA) | COMPLETED | PHASE2 | 2002-08 | | |
| NCT00119587 | Darbepoetin Alfa Treatment of Anemia in Hemodialysis Subjects | COMPLETED | PHASE3 | 2002-08 | 2003-09 | |
| NCT00111475 | Evaluating the Safety and Efficacy of Romiplostim (AMG 531) in Thrombocytopenic Subjects With Immune Thrombocytopenic Purpura (ITP) | COMPLETED | PHASE2 | 2002-07-01 | 2004-06-17 | 2004-06-17 |
| NCT00111761 | Evaluating Panitumumab (ABX-EGF) in Patients With Metastatic Colorectal Cancer | COMPLETED | PHASE2 | 2002-07 | 2008-10 | 2008-02 |
| NCT00049985 | Heart Failure and Anemia | COMPLETED | PHASE2 | 2002-07 | | |
| NCT00117897 | Treatment for Subjects With Non-Hodgkin's Lymphoma | COMPLETED | PHASE2 | 2002-07 | 2004-02 | |
| NCT00115206 | Neulasta® in Subjects With Advanced Non-Small-Cell Lung Cancer (NSCLC) During Chemotherapy | COMPLETED | PHASE4 | 2002-07 | 2004-07 | |
| NCT00042432 | Study for Secondary Hyperparathyroidism in Chronic Renal Insufficiency Patients | COMPLETED | PHASE2 | 2002-06 | 2003-08 | 2003-03 |
| NCT00277160 | A Study of Primary Prophylaxis With Neulasta (Pegfilgrastim) Versus Secondary Prophylaxis After Chemotherapy in Elderly Subjects (>/= 65 Years Old) With Cancer | COMPLETED | PHASE4 | 2002-06 | 2005-01 | 2004-11 |
| NCT00117247 | A Study of Repeat-Dose Subcutaneous Darbepoetin Alfa in Subjects With Congestive Heart Failure and Anemia, and a Single Dose in Healthy Age- and Sex-Matched Control Subjects | COMPLETED | PHASE1, PHASE2 | 2002-06 | 2004-07 | |
| NCT00989092 | Darbepoetin Alfa and Anemia of Cancer | TERMINATED | PHASE2 | 2002-05 | 2004-06 | 2004-01 |
| NCT00043186 | Determine the Efficacy, Safety and Tolerability of Denosumab (AMG 162) in the Treatment of Postmenopausal Women With Low Bone Mineral Density | COMPLETED | PHASE2 | 2002-05 | 2007-06 | 2007-04 |
| NCT00042653 | A Study of an Investigational Medication for the Treatment of Secondary Hyperparathyroidism in Patients on Dialysis | COMPLETED | PHASE3 | 2002-05 | 2003-07 | 2003-07 |
| NCT00369733 | STAAR-3 Clinical Study | COMPLETED | PHASE4 | 2002-05 | 2004-05 | 2004-03 |
| NCT00111995 | Evaluating Aranesp® for the Treatment of Anemia in African-American Subjects With Chronic Renal Failure (CRF) Receiving Hemodialysis | COMPLETED | PHASE4 | 2002-05 | | |
| NCT00356356 | 16.0040 Ankylosing Spondylitis Study | COMPLETED | PHASE3 | 2002-04 | 2006-09 | 2006-08 |
| NCT00038298 | A Rheumatoid Arthritis (RA) Study Treating Signs and Symptoms of RA in People With RA & Receiving Methotrexate | COMPLETED | PHASE2 | 2002-04 | 2004-05 | 2004-05 |
| NCT00111774 | Evaluating ABX-EGF in Patients With Metastatic ColorectalCarcinoma | COMPLETED | PHASE2 | 2002-03 | | |
| NCT00527215 | Phase 2 Study of Darbepoetin Alfa Extended Dosing | COMPLETED | PHASE2 | 2002-03 | 2003-10 | 2003-10 |
| NCT00035594 | Pegfilgrastim as Support to Advanced Breast Cancer Patients Receiving Chemotherapy | COMPLETED | PHASE3 | 2002-02 | 2004-06 | 2004-02 |
| NCT00369772 | STAAR-1 Clinical Study | COMPLETED | PHASE4 | 2002-02 | 2004-05 | |
| NCT00527267 | Safety and Efficacy Study of AMG 073 in Hemodialysis Subjects | COMPLETED | PHASE3 | 2002-02 | 2003-04 | 2003-04 |
| NCT00368901 | STAAR-2 Clinical Study | COMPLETED | PHASE4 | 2002-01 | 2004-05 | 2004-03 |
| NCT00038064 | Anemia in Patients With a Non-Myeloid Malignancy | COMPLETED | PHASE3 | 2002-01 | 2004-04 | 2003-10 |
| NCT00034346 | ABX-EGF in Combination With Paclitaxel and Carboplatin for the Treatment of Advanced Non-Small-Cell Lung Cancer (NSCLC) | COMPLETED | PHASE2 | 2002-01 | | |
| NCT00037635 | A Study of an Investigational Medication for the Treatment of Secondary Hyperparathyroidism in Dialysis Patients | COMPLETED | PHASE3 | 2001-12 | 2003-03 | 2003-03 |
| NCT00035607 | Chemotherapy Related Anemia | COMPLETED | PHASE2 | 2001-12 | 2003-04 | 2002-12 |
| NCT00527085 | 12-month Study of AMG 073 in Renal Osteodystrophy | COMPLETED | PHASE2 | 2001-10 | 2003-08 | 2003-08 |
| NCT00540696 | Study to Develop a Screening Tool for Functional Capacity in Anemic Subjects With Nonmyeloid Malignancies Receiving Chemotherapy and Darbepoetin Alfa | COMPLETED | PHASE2 | 2001-09 | 2003-09 | 2003-06 |
| NCT00537667 | The SPECTRA Study | TERMINATED | PHASE2 | 2001-08 | 2003-06 | 2003-03 |
| NCT00078806 | Safety and Efficacy Study of Etanercept (Enbrel®) In Children With Systemic Onset Juvenile Rheumatoid Arthritis | TERMINATED | PHASE3 | 2001-06-04 | 2004-05-06 | 2004-05-06 |
| NCT00037700 | Evaluation of the Efficacy of Combination Treatment With Anakinra and Pegsunercept in Improving Rheumatoid Arthritis | COMPLETED | PHASE2 | 2001-05 | 2002-12 | |
| NCT00037518 | A Study of an Investigational Medication for Severe Primary Hyperparathyroidism or Parathyroid Cancer | COMPLETED | PHASE4 | 2001-04 | | |
| NCT00936988 | A Multicenter, Open-label Extension Study to Assess the Long-term Safety and Efficacy of an Oral Calcimimetic Agent AMG 073 (Cinacalcet) in Primary Hyperparathyroidism | COMPLETED | PHASE2 | 2000-11 | 2005-12 | 2005-06 |
| NCT03781375 | Etanercept Plus Methotrexate Versus Methotrexate Alone in Children With Polyarticular Course Juvenile Rheumatoid Arthritis | TERMINATED | PHASE3 | 2000-08-24 | 2002-06-24 | 2002-06-20 |
| NCT00527137 | NESP Pediatric Study | COMPLETED | PHASE3 | 2000-08 | 2004-11 | 2004-11 |
| NCT00037648 | Juvenile Rheumatoid Arthritis | COMPLETED | PHASE2 | 2000-07 | 2003-11 | 2003-11 |
| NCT03776058 | Safety, Tolerability, and Clinical Effects of Twice-daily Doses of Cinacalcet (AMG 073) in Adults With Primary Hyperparathyroidism (HPT) | COMPLETED | PHASE2 | 2000-06-15 | 2000-12-26 | 2000-12-26 |
| NCT00526929 | Fixed Dose NESP Study in Subjects With CRI | COMPLETED | PHASE2 | 2000-05 | 2002-02 | 2002-02 |
| NCT00132418 | Study of Enbrel in Rheumatoid Arthritis (RA) Subjects With Comorbid Disorders | COMPLETED | PHASE4 | 2000-04 | 2004-02 | 2004-02 |
| NCT00317499 | Double-blind, Randomized, Placebo-controlled Phase 3 Study of Etanercept in the Treatment of Psoriatic Arthritis and Psoriasis | COMPLETED | PHASE3 | 2000-04 | 2002-07 | 2002-06 |
| NCT00035620 | Pegfilgrastim as Support to Pediatric Sarcoma Patients Receiving Chemotherapy | COMPLETED | PHASE2 | 2000-04 | 2007-04 | 2007-01 |
| NCT00936650 | A Study to Assess the Efficacy and Safety of Twice-Daily Dose Regimens of an Oral Calcimimetic Agent AMG 073 (Cinacalcet) in Primary Hyperparathyroidism (PHPT) | COMPLETED | PHASE2 | 1999-11 | 2001-06 | 2001-03 |
| NCT03776032 | A Novel Erythropoiesis Stimulating Protein (NESP; Darbopoetin Alfa) for the Treatment of Anemia in Lung Cancer Patients Receiving Multi-cycle Platinum-Containing Chemotherapy | COMPLETED | PHASE3 | 1999-09-14 | 2002-02-27 | 2000-11-08 |
| NCT00540384 | Dose-finding Study of Novel Erythropoiesis Stimulating Protein (NESP) for the Treatment of Anaemia in Subjects With Solid Tumours Receiving Multicycle Chemotherapy | COMPLETED | PHASE1, PHASE2 | 1999-07 | 2002-06 | 2002-03 |
| NCT00356590 | Open-Label Extension Treatment With Etanercept (TNFR:Fc) for Participating Patients in Etanercept (TNFR:Fc) Clinical Trial 016.0012 | COMPLETED | PHASE3 | 1998-12 | 2009-04 | 2008-12 |
| NCT03774771 | Safety, Pharmacokinetics, and Clinical Effects of Cinacalcet (AMG 073) in Primary Hyperparathyroidism | COMPLETED | PHASE2 | 1998-09-29 | 1999-12-13 | 1999-12-13 |
| NCT03780959 | Safety and Efficacy of Etanercept (Recombinant Human Tumor Necrosis Factor Receptor Fusion Protein [TNFR:Fc]) in Children With Juvenile Rheumatoid Arthritis (JRA) | COMPLETED | PHASE2, PHASE3 | 1997-05-01 | 1998-07-08 | 1998-07-08 |
| NCT00357903 | Open-Label Extension Treatment With Etanercept (TNFR:Fc) for Participating Patients in Etanercept (TNFR:Fc) Clinical Trials | COMPLETED | PHASE3 | 1997-04 | 2009-04 | 2008-12 |
| NCT00111410 | Evaluating the Effect of Anakinra (r-metHuIL-1ra) on Vaccine AntibodyResponse in Subjects With Rheumatoid Arthritis (RA) | COMPLETED | PHASE4 | | 2003-11 | |
| NCT00111462 | Evaluating Treatment of Anemia in Subjects With Non-Myeloid MalignanciesReceiving Multicycle Chemotherapy | COMPLETED | PHASE2 | | | |
| NCT00113958 | Cinacalcet Study to Reach Kidney Disease Outcomes Quality Initiative (K/DOQI) Levels | COMPLETED | PHASE2 | | | |
| NCT00148421 | Study for the Treatment of Anemia in Patients With Non-myeloid Malignancies Receiving Multicycle Chemotherapy. | COMPLETED | PHASE3 | | | |
| NCT00041665 | Recombinant Human Keratinocyte Growth Factor to Reduce Oral Mucositis in Hematologic Malignancy Patients Undergoing Peripheral Blood Stem Cell Transplantation After Radiation and High-dose Chemotherapy | COMPLETED | PHASE3 | | | |
| NCT00111124 | Enbrel® in Psoriatic Arthritis | COMPLETED | PHASE4 | | | |
| NCT00110903 | Treatment for Subjects With Active Rheumatoid Arthritis (RA) | COMPLETED | PHASE3 | | | |
| NCT00117065 | Study of Transplant Related Anemia Treated With Aranesp® (STRATA) | COMPLETED | PHASE4 | | | |
| NCT00117130 | Study to Evaluate Effectiveness of Aranesp® | COMPLETED | PHASE4 | | | |
| NCT00113776 | Evaluating ABX-EGF Extended Therapy in Subjects With MetastaticColorectal Cancer | COMPLETED | PHASE2 | | | |
| NCT00102830 | Study Evaluating AMG 386 in Adult Patients With Advanced Solid Tumors | COMPLETED | PHASE1 | | | |
| NCT00124111 | A Study of Cyclophosphamide/Methotrexate/5-Fluorouracil (CMF) With Pegfilgrastim in Subjects With Breast Cancer | COMPLETED | PHASE2 | | | |
| NCT00117104 | Evaluating Aranesp® in Subjects With End Stage Renal Disease onChronic Hemodialysis | COMPLETED | PHASE4 | | | |
| NCT00119600 | A Study of AMG 114 Administered by Subcutaneous Injection for the Treatment of Anemia in Subjects With Non-Myeloid Malignancies Receiving Multicycle Chemotherapy | TERMINATED | PHASE1, PHASE2 | | | |
| NCT00036023 | Chemotherapy Related Anemia in Patients With Non-Myeloid Malignancies | COMPLETED | PHASE2 | | | |
| NCT00111111 | An Evaluation of Etanercept in the Treatment of Subjects With Psoriasis | COMPLETED | PHASE3 | | | |
| NCT00117078 | Aranesp® Monthly Preference Study - 2 | COMPLETED | PHASE4 | | | |
| NCT00115414 | Same Day Dosing of Pegfilgrastim in Breast Cancer Patients Undergoing Chemotherapy (TAC) | COMPLETED | PHASE2 | | | |
| NCT00124098 | An Evaluation of Aranesp® in Subjects With Anaemic Chronic Kidney Disease (CKD) | COMPLETED | PHASE3 | | | |
| NCT00117455 | A Study of Peripheral Blood Progenitor Cell (PBPC) Mobilisation by Chemotherapy With Pegfilgrastim or Filgrastim in Subjects With Non-Hodgkin's Lymphoma | COMPLETED | PHASE2 | | | |
| NCT00121043 | Evaluating Kineret® (Anakinra) in Rheumatoid Arthritis (RA) Subjects Using aSelf-Reported Questionnaire | COMPLETED | PHASE4 | | | |
| NCT00044902 | Monoclonal Antibody Treatment for Non-Hodgkin's Lymphoma (Low-Grade) | COMPLETED | PHASE2 | | | |
| NCT00117091 | Anakinra (Kineret®) in Combination With Disease Modifying Anti-Rheumatic Drugs (DMARDS) in Subjects With Active Rheumatoid Arthritis (RA) | COMPLETED | PHASE3 | | | |
| NCT00002433 | The Effects of r-metHuIFN-Gamma on the Lungs of Patients With AIDS | COMPLETED | NA | | | |
| NCT00002126 | A Randomized, Controlled, Multicenter Trial of Filgrastim (Recombinant-Methionyl Human Granulocyte Colony Stimulating Factor; G-CSF) for the Prevention of Grade 4 Neutropenia in Patients With HIV Infection. | COMPLETED | PHASE2 | | | |
| NCT00002037 | Evaluation of the Therapeutic Benefit of r-metHuIFN- Gamma in AIDS Patients With Disseminated Mycobacterium Avium-Intracellulare (MAI) Infection: A Multi-Centered Pilot Study | COMPLETED | NA | | | |
| NCT00002255 | An Open-Label Phase I/II Study of Recombinant Granulocyte Colony Stimulating Factor (r-metHuG-CSF) and Recombinant Erythropoietin (rHuEPO) Given Subcutaneously Along With Zidovudine (AZT) to Patients With the Acquired Immune Deficiency Syndrome (AIDS) or Severe AIDS-Related Complex (ARC) | COMPLETED | PHASE1 | | | |
| NCT00002281 | A Study of Granulocyte Colony-Stimulating Factor Plus Recombinant Erythropoietin Plus Zidovudine in Patients With AIDS or AIDS-Related Complex | COMPLETED | NA | | | |