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| NCT06952634 | An Investigational Study of ESK-001 in Participants With Normal Liver Function and Participants With Mild, Moderate, and Severe Liver Damage | RECRUITING | PHASE1 | 2025-04-29 | 2025-12 | 2025-12 |
| NCT06846541 | Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis | RECRUITING | PHASE3 | 2025-01-08 | 2028-11 | 2028-11 |
| NCT06588738 | A Study in Patients With Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001 | ACTIVE_NOT_RECRUITING | PHASE3 | 2024-08-20 | 2025-12 | 2025-09 |
| NCT06586112 | A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque Psoriasis | ACTIVE_NOT_RECRUITING | PHASE3 | 2024-07-25 | 2025-12 | 2025-09 |
| NCT05966480 | Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus | ACTIVE_NOT_RECRUITING | PHASE2 | 2023-06-26 | 2027-09-01 | 2026-07-01 |
| NCT05953688 | POC Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Active Intermediate, Posterior, or Pan NIU | TERMINATED | PHASE2 | 2023-06-14 | 2024-08-13 | 2024-08-13 |
| NCT05739435 | Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis | ACTIVE_NOT_RECRUITING | PHASE2 | 2023-01-17 | 2026-12-30 | 2026-12-01 |
| NCT05600036 | A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Plaque Psoriasis | COMPLETED | PHASE2 | 2022-09-27 | 2023-07-25 | 2023-06-29 |
| NCT05431634 | Multiple Dose Study to Determine Safety and Tolerability of ESK-001 in Healthy Participants | COMPLETED | PHASE1 | 2022-05-12 | 2022-12-31 | 2022-12-01 |
| NCT05330858 | Relative Bioavailability of ESK-001 Tablet Versus Liquid in Healthy Participants | COMPLETED | PHASE1 | 2022-03-17 | 2022-09-20 | 2022-06-30 |