{"nct_id":"NCT06439082","title":"A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)","status":"RECRUITING","status_verified_date":"2025-09","start_date":"2024-10-24","start_date_type":"ACTUAL","primary_completion_date":"2029-03-23","primary_completion_date_type":"ESTIMATED","completion_date":"2030-04-19","completion_date_type":"ESTIMATED","phases":["PHASE3"],"tickers":["NVS"]}